David G. Miguez

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Head of the [http://sysbio.openwetware.org/  Biophysics and Systems Biology Lab  ]
Head of the [http://sysbio.openwetware.org/  Biophysics and Systems Biology Lab  ]
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Departamento de Física de la Materia Condensada, Universidad Autónoma de Madrid, 28014 Madrid
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Departamento de Física de la Materia Condensada, Universidad Autónoma de Madrid, 28049 Madrid
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''Interests:'' Systems Biology, Biophysics
''Interests:'' Systems Biology, Biophysics
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Editor of [http://www.iospress.nl/journal/in-silico-biology/ In Silico Biology]
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==Contact==
==Contact==
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==Publications==
==Publications==
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#  D. G. Míguez,  ''[http://link.springer.com/article/10.1007%2Fs12539-013-0165-x Network Nonlinearities in Drug Treatment]'', Interdisciplinary Sciences: Computational Life Sciences 5,85 (2013).
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#  P. Gregorio-Godoy, D. G. Míguez, ''[http://digital-library.theiet.org/content/journals/10.1049/iet-syb.2012.0026 Synthetic approaches to study transcriptional networks and noise in mammalian systems]'', IET Systems Biology 7,11 (2013).
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# V. Doldán-Martelli, R. Guantes, D. G. Míguez, ''[http://www.nature.com/psp/journal/v2/n2/full/psp20132a.html  A Mathematical Model for the Rational Design of Chimeric Ligands in Selective Drug Therapies]'', CPT: Pharmacometrics & Systems Pharmacology '''2''', e26 (2013).
# V. Doldán-Martelli, D. G. Míguez, ''Theoretical Approaches to Growth Hormone Signaling'', in 'Growth Hormones: Synthesis, Regulation and Health Implications', Eds. A. Andersdtr and J.  Anderssen Nova Publishers ISBN 9781619426818 (2012).
# V. Doldán-Martelli, D. G. Míguez, ''Theoretical Approaches to Growth Hormone Signaling'', in 'Growth Hormones: Synthesis, Regulation and Health Implications', Eds. A. Andersdtr and J.  Anderssen Nova Publishers ISBN 9781619426818 (2012).
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# D. G. Míguez,  ''Network Nonlinearities in Drug Treatment'' (in press).
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# D. G. Míguez, Milos Dolnik, Irving Epstein and Alberto P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v84/i4/e046210 Interaction Of Chemical Patterns in Coupled Layers]'', Phys. Rev. E, '''84''', 046210 (2011).
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# D. G. Míguez, Milos Dolnik, Irving Epstein and Alberto P. Muñuzuri, ''Interaction Of Chemical Patterns in Coupled Layers'' Phys. Rev. E, '''84''', 046210 (2011).
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# D. G. Míguez, ''[http://www.sciencedirect.com/science/article/pii/S0301462210000402 The role of asymmetric binding in ligand-receptor systems with 1:2 interaction ratio]''  Biophys Chem '''148''', 74-81 (2010)
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# D. G. Míguez, ''The role of asymmetric binding in ligand-receptor systems with 1:2 interaction ratio''  Biophys Chem '''148''', 74-81 (2010)
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# D.G. Míguez, ''Forcing of Nonlinear Pattern Formation Systems'',  Lambert Academic Publishing, ISBN 9783838364223 (2010) [http://www.amazon.com/Forcing-Nonlinear-Pattern-Formation-Systems/dp/3838364228 Book].
# D.G. Míguez, ''Forcing of Nonlinear Pattern Formation Systems'',  Lambert Academic Publishing, ISBN 9783838364223 (2010) [http://www.amazon.com/Forcing-Nonlinear-Pattern-Formation-Systems/dp/3838364228 Book].
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# D. G. Míguez, P. McGraw, A. P. Muñuzuri and M. Menzinger, ''Selection of Flow-Distributed Oscillation and Turing Patterns by Boundary Forcing in a Linearly Growing, Oscillating Medium'', Phys. Rev. E, '''80''', 026208 (2009).
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# D. G. Míguez, P. McGraw, A. P. Muñuzuri and M. Menzinger, ''[http://pre.aps.org/abstract/PRE/v80/i2/e026208 Selection of Flow-Distributed Oscillation and Turing Patterns by Boundary Forcing in a Linearly Growing, Oscillating Medium]'', Phys. Rev. E, '''80''', 026208 (2009).
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# I. A. Swinburne, D. G. Míguez, D. Landgraf, and P. A. Silver, ''Intron length increases oscillatory periods of gene expression in animal cells'', Genes & Dev., '''22''' 2008, 2342-2346 (2008).
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# I. A. Swinburne, D. G. Míguez, D. Landgraf, and P. A. Silver, ''[http://genesdev.cshlp.org/content/22/17/2342.full Intron length increases oscillatory periods of gene expression in animal cells]'', Genes & Dev., '''22''' 2008, 2342-2346 (2008).
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# S. Alonso, D. G. Míguez, F. Sagués, ''Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium'', Europhys. Lett, '''81''', 30006 (2008).  
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# S. Alonso, D. G. Míguez, F. Sagués, ''[http://iopscience.iop.org/0295-5075/81/3/30006 Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium]'', Europhys. Lett, '''81''', 30006 (2008).  
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# D. G. Míguez, V. K. Vanag, I. R. Epstein, ''Fronts and pulses in an enzymatic reaction with glucose oxidase'' P.N.A.S. '''104''', 6992 (2007).
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# D. G. Míguez, V. K. Vanag, I. R. Epstein, ''[http://www.pnas.org/content/104/17/6992.full Fronts and pulses in an enzymatic reaction with glucose oxidase]'' P.N.A.S. '''104''', 6992 (2007).
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# V. K. Vanag, D.G. Míguez, I. R. Epstein, ''Designing an Enzymatic Oscillator: Bistability and Feedback Control led Oscillations with Glucose Oxidase in a CSTR'', J. Phys. Chem. '''125''', 194515 (2006).
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# V. K. Vanag, D.G. Míguez, I. R. Epstein, ''[http://jcp.aip.org/resource/1/jcpsa6/v125/i19/p194515_s1 Designing an Enzymatic Oscillator: Bistability and Feedback Control led Oscillations with Glucose Oxidase in a CSTR]'', J. Phys. Chem. '''125''', 194515 (2006).
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# D.G. Míguez, S. Alonso, A.P. Muñuzuri, F. Sagués, ''Turing patterns of oscillating spots'', Phys. Rev. Lett, '''97''', 178301 (2006).  
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# D.G. Míguez, S. Alonso, A.P. Muñuzuri, F. Sagués, ''[http://prl.aps.org/abstract/PRL/v97/i17/e178301 Experimental evidence of localized oscillations in the photosensitive chlorine dioxide-iodine-malonic acid reaction]'', Phys. Rev. Lett, '''97''', 178301 (2006).  
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# D. G. Míguez, A. P. Muñuzuri, ''On the orientation of stripes in fish skin patterning'', Biophys. Chem. '''124''', 161 (2006).  
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# D. G. Míguez, A. P. Muñuzuri, ''[http://www.sciencedirect.com/science/article/pii/S0301462206002122 On the orientation of stripes in fish skin patterning]'', Biophys. Chem. '''124''', 161 (2006).  
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# D. G. Míguez, R. A. Satnoianu, A. P. Muñuzuri, ''Experimental steady pattern formation in reaction-diffusion-advection systems'', Phys. Rev. E '''73''', 025201 (R) (2006).
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# D. G. Míguez, R. A. Satnoianu, A. P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v73/i2/e025201 Experimental steady pattern formation in reaction-diffusion-advection systems]'', Phys. Rev. E '''73''', 025201 (R) (2006).
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# D. G. Míguez, M. Dolnik, A. P. Muñuzuri, L. Kramer, ''Effect of Axial Growth on Turing Pattern Formation''.  Phys. Rev. Lett '''96''', 048304 (2006).
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# D. G. Míguez, M. Dolnik, A. P. Muñuzuri, L. Kramer, ''[http://prl.aps.org/abstract/PRL/v96/i4/e048304 Effect of Axial Growth on Turing Pattern Formation]''.  Phys. Rev. Lett '''96''', 048304 (2006).
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# D. G. Míguez, G. Izús, A. P. Muñuzuri, ''Robustness and Stability of Flow-and-Diffusion Structures'', Phys. Rev. E '''73''', 016207 (2006).
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# D. G. Míguez, G. Izús, A. P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v73/i1/e016207 Robustness and Stability of Flow-and-Diffusion Structures]'', Phys. Rev. E '''73''', 016207 (2006).
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# D. G. Miguez, V. Perez-Villar, and A. P. Munuzuri, ''Turing instability controlled by spatiotemporal imposed dynamics'', Phys. Rev. E '''71''', 066217 (2005).
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# D. G. Miguez, V. Perez-Villar, and A. P. Munuzuri, ''[http://pre.aps.org/abstract/PRE/v71/i6/e066217 Turing instability controlled by spatiotemporal imposed dynamics]'', Phys. Rev. E '''71''', 066217 (2005).
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# F. Sagués, D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, L. Kramer, ''Spatio-Temporal Forcing of Turing Patterns'', Physica D '''199''', 235 (2004) .
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# F. Sagués, D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, L. Kramer, ''[http://www.sciencedirect.com/science/article/pii/S0167278904003197 Travelling-stripe forcing of Turing patterns]'', Physica D '''199''', 235 (2004).
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# D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, F. Sagués, L. Kramer, ''Traveling-Stripe Forcing Generates Hexagonal Patterns'', Phys. Rev. Lett. '''93''', 048303 (2004) .
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# D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, F. Sagués, L. Kramer, ''[http://prl.aps.org/abstract/PRL/v93/i4/e048303 Traveling-Stripe Forcing Generates Hexagonal Patterns]'', Phys. Rev. Lett. '''93''', 048303 (2004).
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# M. Kærn, D. G. Míguez, A. P. Muñuzuri, M. Menzinger, ''Control of chemical pattern formation by a clock-and-wavefront type mechanism'', Biophys. Chem. '''110''', 231 (2004). '''Shared 1st authorship'''.
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# M. Kærn, D. G. Míguez, A. P. Muñuzuri, M. Menzinger, ''[http://www.sciencedirect.com/science/article/pii/S030146220400078X Control of chemical pattern formation by a clock-and-wavefront type mechanism]'', Biophys. Chem. '''110''', 231 (2004). '''Shared 1st authorship'''.
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# B. Peña, C. Pérez-García, A. Sanz-Anchelergues, ''Transverse instabilities in chemical Turing patterns of stripes'', D. G. Míguez, A. P. Muñuzuri, Phys. Rev. E '''68''', 056206 (2003) .
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# B. Peña, C. Pérez-García, A. Sanz-Anchelergues, D. G. Míguez, A. P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v68/i5/e056206 Transverse instabilities in chemical Turing patterns of stripes]'', Phys. Rev. E '''68''', 056206 (2003).
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# S. Rüdiger, D. G. Míguez, A. P. Muñuzuri, F. Sagués, J. Casademunt, ''Dynamics of Turing Patterns under Spatiotemporal Forcing'', Phys. Rev. Lett '''90''', 128301 (2003).
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# S. Rüdiger, D. G. Míguez, A. P. Muñuzuri, F. Sagués, J. Casademunt, ''[http://prl.aps.org/abstract/PRL/v90/i12/e128301 Dynamics of Turing Patterns under Spatiotemporal Forcing]'', Phys. Rev. Lett '''90''', 128301 (2003).
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*'''[[User:DavidMiguez|David]]''':
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*'''[[User:DavidMiguez|David]] 14:50, 18 June 2013 (EDT)'''

Revision as of 14:50, 18 June 2013

Personal Info

David G. Míguez

Head of the Biophysics and Systems Biology Lab

Departamento de Física de la Materia Condensada, Universidad Autónoma de Madrid, 28049 Madrid


Previous Research Institutions:

  • 2001-2005 PhD Thesis at Group of Nonlinear Physics at Santiago de Compostela (Galicia, Spain),
  • 2005-2006 Group of Complex Systems, Brandeis University (MA)
  • 2006-2009 Department of Systems Biology, Harvard Medical School (MA),
  • 2009-2011 Instituto de Biología Molecular de Barcelona (CSIC, Spain)

Background: Nonlinear Dynamics, reaction-diffusion, autocatalitic and bistable systems, feedback, pH oscillators, Turing Patterns, Enzyme kinetics, Systems Biology in Cancer, Signaling pathways.

Interests: Systems Biology, Biophysics

Editor of In Silico Biology

Contact

David G. Míguez

e-mail: david DOT gomez DOT miguez AT uam DOT es

Depto. de Fisica de la Materia Condensada Facultad de Ciencias Universidad Autonoma de Madrid Cantoblanco, 28049 Madrid (SPAIN)

phone (+34) 657-929-775 work (+34) 914-978-076

Publications

  1. D. G. Míguez, Network Nonlinearities in Drug Treatment, Interdisciplinary Sciences: Computational Life Sciences 5,85 (2013).
  2. P. Gregorio-Godoy, D. G. Míguez, Synthetic approaches to study transcriptional networks and noise in mammalian systems, IET Systems Biology 7,11 (2013).
  3. V. Doldán-Martelli, R. Guantes, D. G. Míguez, A Mathematical Model for the Rational Design of Chimeric Ligands in Selective Drug Therapies, CPT: Pharmacometrics & Systems Pharmacology 2, e26 (2013).
  4. V. Doldán-Martelli, D. G. Míguez, Theoretical Approaches to Growth Hormone Signaling, in 'Growth Hormones: Synthesis, Regulation and Health Implications', Eds. A. Andersdtr and J. Anderssen Nova Publishers ISBN 9781619426818 (2012).
  5. D. G. Míguez, Milos Dolnik, Irving Epstein and Alberto P. Muñuzuri, Interaction Of Chemical Patterns in Coupled Layers, Phys. Rev. E, 84, 046210 (2011).
  6. D. G. Míguez, The role of asymmetric binding in ligand-receptor systems with 1:2 interaction ratio Biophys Chem 148, 74-81 (2010)
  7. D.G. Míguez, Forcing of Nonlinear Pattern Formation Systems, Lambert Academic Publishing, ISBN 9783838364223 (2010) Book.
  8. D. G. Míguez, P. McGraw, A. P. Muñuzuri and M. Menzinger, Selection of Flow-Distributed Oscillation and Turing Patterns by Boundary Forcing in a Linearly Growing, Oscillating Medium, Phys. Rev. E, 80, 026208 (2009).
  9. I. A. Swinburne, D. G. Míguez, D. Landgraf, and P. A. Silver, Intron length increases oscillatory periods of gene expression in animal cells, Genes & Dev., 22 2008, 2342-2346 (2008).
  10. S. Alonso, D. G. Míguez, F. Sagués, Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium, Europhys. Lett, 81, 30006 (2008).
  11. D. G. Míguez, V. K. Vanag, I. R. Epstein, Fronts and pulses in an enzymatic reaction with glucose oxidase P.N.A.S. 104, 6992 (2007).
  12. V. K. Vanag, D.G. Míguez, I. R. Epstein, Designing an Enzymatic Oscillator: Bistability and Feedback Control led Oscillations with Glucose Oxidase in a CSTR, J. Phys. Chem. 125, 194515 (2006).
  13. D.G. Míguez, S. Alonso, A.P. Muñuzuri, F. Sagués, Experimental evidence of localized oscillations in the photosensitive chlorine dioxide-iodine-malonic acid reaction, Phys. Rev. Lett, 97, 178301 (2006).
  14. D. G. Míguez, A. P. Muñuzuri, On the orientation of stripes in fish skin patterning, Biophys. Chem. 124, 161 (2006).
  15. D. G. Míguez, R. A. Satnoianu, A. P. Muñuzuri, Experimental steady pattern formation in reaction-diffusion-advection systems, Phys. Rev. E 73, 025201 (R) (2006).
  16. D. G. Míguez, M. Dolnik, A. P. Muñuzuri, L. Kramer, Effect of Axial Growth on Turing Pattern Formation. Phys. Rev. Lett 96, 048304 (2006).
  17. D. G. Míguez, G. Izús, A. P. Muñuzuri, Robustness and Stability of Flow-and-Diffusion Structures, Phys. Rev. E 73, 016207 (2006).
  18. D. G. Miguez, V. Perez-Villar, and A. P. Munuzuri, Turing instability controlled by spatiotemporal imposed dynamics, Phys. Rev. E 71, 066217 (2005).
  19. F. Sagués, D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, L. Kramer, Travelling-stripe forcing of Turing patterns, Physica D 199, 235 (2004).
  20. D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, F. Sagués, L. Kramer, Traveling-Stripe Forcing Generates Hexagonal Patterns, Phys. Rev. Lett. 93, 048303 (2004).
  21. M. Kærn, D. G. Míguez, A. P. Muñuzuri, M. Menzinger, Control of chemical pattern formation by a clock-and-wavefront type mechanism, Biophys. Chem. 110, 231 (2004). Shared 1st authorship.
  22. B. Peña, C. Pérez-García, A. Sanz-Anchelergues, D. G. Míguez, A. P. Muñuzuri, Transverse instabilities in chemical Turing patterns of stripes, Phys. Rev. E 68, 056206 (2003).
  23. S. Rüdiger, D. G. Míguez, A. P. Muñuzuri, F. Sagués, J. Casademunt, Dynamics of Turing Patterns under Spatiotemporal Forcing, Phys. Rev. Lett 90, 128301 (2003).
  • David 14:50, 18 June 2013 (EDT)
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