David G. Miguez

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[[Image:davidgmiguez.jpg|150 px]]
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==Personal Info==
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=Personal Info=
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[[Image:davidgmiguez.jpg|160 px|left|David G. Míguez]]
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''Current position:'' Marie Curie fellow at Elisa Martí's Lab. Instituto de Biologia Molecular de Barcelona, CISC.
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''Background:'' Nonlinear Dynamics, reaction-diffusion, autocatalitic and bistable systems, feedback, pH oscillators, Turing Patterns, Enzyme kinetics, Systems Biology in Cancer, Signaling pathways.
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Head of the [http://sysbio.openwetware.org/  Biophysics and Systems Biology Lab  ]
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''Interest:'' Development of Central Nervous System in Vertebrates
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Departamento de Física de la Materia Condensada, Universidad Autónoma de Madrid, 28049 Madrid
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=Contact=
 
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David G. Míguez
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''Previous Research Institutions'': 
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e-mail: davidgmiguez  ''AT'' gmail DOT com
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*2001-2005 PhD Thesis at Group of Nonlinear Physics at Santiago de Compostela (Galicia, Spain),
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Personal Web: http://silver.med.harvard.edu/david/
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*2005-2006 Group of Complex Systems, Brandeis University (MA)
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*2006-2009  Department of Systems Biology, Harvard Medical School (MA),
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*2009-2011 Instituto de Biología Molecular de Barcelona (CSIC, Spain)
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''Background:'' Nonlinear Dynamics, reaction-diffusion, autocatalitic and bistable systems, feedback, pH oscillators, Turing Patterns, Enzyme kinetics, Systems Biology in Cancer, Signaling pathways.
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''Interests:'' Systems Biology, Biophysics
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Editor of [http://www.iospress.nl/journal/in-silico-biology/ In Silico Biology]
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==Contact==
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David G. Míguez
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Blog: http://www.universonica.net
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e-mail: david DOT gomez DOT miguez  ''AT'' uam DOT es
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Instituto de Biologia Molecular de Barcelona, CSIC
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Depto. de Fisica de la Materia Condensada
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Parc Cientific de Barcelona
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Facultad de Ciencias
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C/Baldiri i Reixac 15-21
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Universidad Autonoma de Madrid
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Barcelona 08028
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Cantoblanco,
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28049 Madrid (SPAIN)
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phone 34-657-929-775
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phone (+34) 657-929-775
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fax 34-93-4034979
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work  (+34) 914-978-076
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=Publications=
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==Publications==
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# D. G. Míguez, P. McGraw, A. P. Muñuzuri and M. Menzinger, "Selection of Flow-Distributed Oscillation and Turing Patterns by Boundary Forcing in a Linearly Growing, Oscillating Medium", Submitted.
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#  D. G. Míguez,  ''[http://link.springer.com/article/10.1007%2Fs12539-013-0165-x Network Nonlinearities in Drug Treatment]'', Interdisciplinary Sciences: Computational Life Sciences 5,85 (2013).
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# I. A. Swinburne, D. G. Míguez, D. Landgraf, and P. A. Silver, "Intron length increases oscillatory periods of gene expression in animal cells", Genes & Dev., (2008) in press.
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#  P. Gregorio-Godoy, D. G. Míguez, ''[http://digital-library.theiet.org/content/journals/10.1049/iet-syb.2012.0026 Synthetic approaches to study transcriptional networks and noise in mammalian systems]'', IET Systems Biology 7,11 (2013).
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# S. Alonso, D. G. Míguez, F. Sagués, “Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium”, Europhys. Lett, '''81''', 30006 (2008).  
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# V. Doldán-Martelli, R. Guantes, D. G. Míguez, ''[http://www.nature.com/psp/journal/v2/n2/full/psp20132a.html  A Mathematical Model for the Rational Design of Chimeric Ligands in Selective Drug Therapies]'', CPT: Pharmacometrics & Systems Pharmacology '''2''', e26 (2013).
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# D. G. Míguez, V. K. Vanag, I. R. Epstein, “Fronts and pulses in an enzymatic reaction with glucose oxidase" P.N.A.S. '''104''', 6992 (2007).
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# V. Doldán-Martelli, D. G. Míguez, ''Theoretical Approaches to Growth Hormone Signaling'', in 'Growth Hormones: Synthesis, Regulation and Health Implications', Eds. A. Andersdtr and J.  Anderssen Nova Publishers ISBN 9781619426818 (2012).
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# V. K. Vanag, D.G. Míguez, I. R. Epstein, “Designing an Enzymatic Oscillator: Bistability and Feedback Control led Oscillations with Glucose Oxidase in a CSTR”, J. Phys. Chem. '''125''', 194515 (2006).
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# D. G. Míguez, Milos Dolnik, Irving Epstein and Alberto P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v84/i4/e046210 Interaction Of Chemical Patterns in Coupled Layers]'', Phys. Rev. E, '''84''', 046210 (2011).
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# D.G. Míguez, S. Alonso, A.P. Muñuzuri, F. Sagués, “Turing patterns of oscillating spots”, Phys. Rev. Lett, '''97''', 178301 (2006).  
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# D. G. Míguez, ''[http://www.sciencedirect.com/science/article/pii/S0301462210000402 The role of asymmetric binding in ligand-receptor systems with 1:2 interaction ratio]''  Biophys Chem '''148''', 74-81 (2010)
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# D. G. Míguez, A. P. Muñuzuri,“On the orientation of stripes in fish skin patterning”, Biophys. Chem. '''124''', 161 (2006).  
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# D.G. Míguez, ''Forcing of Nonlinear Pattern Formation Systems'',  Lambert Academic Publishing, ISBN 9783838364223 (2010) [http://www.amazon.com/Forcing-Nonlinear-Pattern-Formation-Systems/dp/3838364228 Book].
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# D. G. Míguez, R. A. Satnoianu, A. P. Muñuzuri, "Experimental steady pattern formation in reaction-diffusion-advection systems", Phys. Rev. E '''73''', 025201 (R) (2006).
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# D. G. Míguez, P. McGraw, A. P. Muñuzuri and M. Menzinger, ''[http://pre.aps.org/abstract/PRE/v80/i2/e026208 Selection of Flow-Distributed Oscillation and Turing Patterns by Boundary Forcing in a Linearly Growing, Oscillating Medium]'', Phys. Rev. E, '''80''', 026208 (2009).
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# D. G. Míguez, M. Dolnik, A. P. Muñuzuri, L. Kramer, "Effect of Axial Growth on Turing Pattern Formation".  Phys. Rev. Lett '''96''', 048304 (2006).
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# I. A. Swinburne, D. G. Míguez, D. Landgraf, and P. A. Silver, ''[http://genesdev.cshlp.org/content/22/17/2342.full Intron length increases oscillatory periods of gene expression in animal cells]'', Genes & Dev., '''22''' 2008, 2342-2346 (2008).
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# D. G. Míguez, G. Izús, A. P. Muñuzuri, "Robustness and Stability of Flow-and-Diffusion Structures", Phys. Rev. E '''73''', 016207 (2006).
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# S. Alonso, D. G. Míguez, F. Sagués, ''[http://iopscience.iop.org/0295-5075/81/3/30006 Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium]'', Europhys. Lett, '''81''', 30006 (2008).  
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# D. G. Miguez, V. Perez-Villar, and A. P. Munuzuri, "Turing instability controlled by spatiotemporal imposed dynamics", Phys. Rev. E '''71''', 066217 (2005).
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# D. G. Míguez, V. K. Vanag, I. R. Epstein, ''[http://www.pnas.org/content/104/17/6992.full Fronts and pulses in an enzymatic reaction with glucose oxidase]'' P.N.A.S. '''104''', 6992 (2007).
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# F. Sagués, D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, L. Kramer, "Spatio-Temporal Forcing of Turing Patterns", Physica D '''199''', 235 (2004) .
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# V. K. Vanag, D.G. Míguez, I. R. Epstein, ''[http://jcp.aip.org/resource/1/jcpsa6/v125/i19/p194515_s1 Designing an Enzymatic Oscillator: Bistability and Feedback Control led Oscillations with Glucose Oxidase in a CSTR]'', J. Phys. Chem. '''125''', 194515 (2006).
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# D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, F. Sagués, L. Kramer, "Traveling-Stripe Forcing Generates Hexagonal Patterns", Phys. Rev. Lett. '''93''', 048303 (2004) .
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# D.G. Míguez, S. Alonso, A.P. Muñuzuri, F. Sagués, ''[http://prl.aps.org/abstract/PRL/v97/i17/e178301 Experimental evidence of localized oscillations in the photosensitive chlorine dioxide-iodine-malonic acid reaction]'', Phys. Rev. Lett, '''97''', 178301 (2006).  
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# M. Kærn, D. G. Míguez, A. P. Muñuzuri, M. Menzinger, "Control of chemical pattern formation by a clock-and-wavefront type mechanism", Biophys. Chem. '''110''', 231 (2004). '''Shared 1st authorship'''.
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# D. G. Míguez, A. P. Muñuzuri, ''[http://www.sciencedirect.com/science/article/pii/S0301462206002122 On the orientation of stripes in fish skin patterning]'', Biophys. Chem. '''124''', 161 (2006).  
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# B. Peña, C. Pérez-García, A. Sanz-Anchelergues, "Transverse instabilities in chemical Turing patterns of stripes", D. G. Míguez, A. P. Muñuzuri, Phys. Rev. E '''68''', 056206 (2003) .
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# D. G. Míguez, R. A. Satnoianu, A. P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v73/i2/e025201 Experimental steady pattern formation in reaction-diffusion-advection systems]'', Phys. Rev. E '''73''', 025201 (R) (2006).
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# S. Rüdiger, D. G. Míguez, A. P. Muñuzuri, F. Sagués, J. Casademunt, "Dynamics of Turing Patterns under Spatiotemporal Forcing", Phys. Rev. Lett '''90''', 128301 (2003).
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# D. G. Míguez, M. Dolnik, A. P. Muñuzuri, L. Kramer, ''[http://prl.aps.org/abstract/PRL/v96/i4/e048304 Effect of Axial Growth on Turing Pattern Formation]''.  Phys. Rev. Lett '''96''', 048304 (2006).
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# D. G. Míguez, G. Izús, A. P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v73/i1/e016207 Robustness and Stability of Flow-and-Diffusion Structures]'', Phys. Rev. E '''73''', 016207 (2006).
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# D. G. Miguez, V. Perez-Villar, and A. P. Munuzuri, ''[http://pre.aps.org/abstract/PRE/v71/i6/e066217 Turing instability controlled by spatiotemporal imposed dynamics]'', Phys. Rev. E '''71''', 066217 (2005).
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# F. Sagués, D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, L. Kramer, ''[http://www.sciencedirect.com/science/article/pii/S0167278904003197 Travelling-stripe forcing of Turing patterns]'', Physica D '''199''', 235 (2004).
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# D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, F. Sagués, L. Kramer, ''[http://prl.aps.org/abstract/PRL/v93/i4/e048303 Traveling-Stripe Forcing Generates Hexagonal Patterns]'', Phys. Rev. Lett. '''93''', 048303 (2004).
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# M. Kærn, D. G. Míguez, A. P. Muñuzuri, M. Menzinger, ''[http://www.sciencedirect.com/science/article/pii/S030146220400078X Control of chemical pattern formation by a clock-and-wavefront type mechanism]'', Biophys. Chem. '''110''', 231 (2004). '''Shared 1st authorship'''.
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# B. Peña, C. Pérez-García, A. Sanz-Anchelergues, D. G. Míguez, A. P. Muñuzuri, ''[http://pre.aps.org/abstract/PRE/v68/i5/e056206 Transverse instabilities in chemical Turing patterns of stripes]'',  Phys. Rev. E '''68''', 056206 (2003).
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# S. Rüdiger, D. G. Míguez, A. P. Muñuzuri, F. Sagués, J. Casademunt, ''[http://prl.aps.org/abstract/PRL/v90/i12/e128301 Dynamics of Turing Patterns under Spatiotemporal Forcing]'', Phys. Rev. Lett '''90''', 128301 (2003).
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Updated by: [[User:DavidMiguez|David]] 15:24, 8 August 2008 (UTC)
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*'''[[User:DavidMiguez|David]] 14:50, 18 June 2013 (EDT)'''

Revision as of 14:50, 18 June 2013

Personal Info

David G. Míguez

Head of the Biophysics and Systems Biology Lab

Departamento de Física de la Materia Condensada, Universidad Autónoma de Madrid, 28049 Madrid


Previous Research Institutions:

  • 2001-2005 PhD Thesis at Group of Nonlinear Physics at Santiago de Compostela (Galicia, Spain),
  • 2005-2006 Group of Complex Systems, Brandeis University (MA)
  • 2006-2009 Department of Systems Biology, Harvard Medical School (MA),
  • 2009-2011 Instituto de Biología Molecular de Barcelona (CSIC, Spain)

Background: Nonlinear Dynamics, reaction-diffusion, autocatalitic and bistable systems, feedback, pH oscillators, Turing Patterns, Enzyme kinetics, Systems Biology in Cancer, Signaling pathways.

Interests: Systems Biology, Biophysics

Editor of In Silico Biology

Contact

David G. Míguez

e-mail: david DOT gomez DOT miguez AT uam DOT es

Depto. de Fisica de la Materia Condensada Facultad de Ciencias Universidad Autonoma de Madrid Cantoblanco, 28049 Madrid (SPAIN)

phone (+34) 657-929-775 work (+34) 914-978-076

Publications

  1. D. G. Míguez, Network Nonlinearities in Drug Treatment, Interdisciplinary Sciences: Computational Life Sciences 5,85 (2013).
  2. P. Gregorio-Godoy, D. G. Míguez, Synthetic approaches to study transcriptional networks and noise in mammalian systems, IET Systems Biology 7,11 (2013).
  3. V. Doldán-Martelli, R. Guantes, D. G. Míguez, A Mathematical Model for the Rational Design of Chimeric Ligands in Selective Drug Therapies, CPT: Pharmacometrics & Systems Pharmacology 2, e26 (2013).
  4. V. Doldán-Martelli, D. G. Míguez, Theoretical Approaches to Growth Hormone Signaling, in 'Growth Hormones: Synthesis, Regulation and Health Implications', Eds. A. Andersdtr and J. Anderssen Nova Publishers ISBN 9781619426818 (2012).
  5. D. G. Míguez, Milos Dolnik, Irving Epstein and Alberto P. Muñuzuri, Interaction Of Chemical Patterns in Coupled Layers, Phys. Rev. E, 84, 046210 (2011).
  6. D. G. Míguez, The role of asymmetric binding in ligand-receptor systems with 1:2 interaction ratio Biophys Chem 148, 74-81 (2010)
  7. D.G. Míguez, Forcing of Nonlinear Pattern Formation Systems, Lambert Academic Publishing, ISBN 9783838364223 (2010) Book.
  8. D. G. Míguez, P. McGraw, A. P. Muñuzuri and M. Menzinger, Selection of Flow-Distributed Oscillation and Turing Patterns by Boundary Forcing in a Linearly Growing, Oscillating Medium, Phys. Rev. E, 80, 026208 (2009).
  9. I. A. Swinburne, D. G. Míguez, D. Landgraf, and P. A. Silver, Intron length increases oscillatory periods of gene expression in animal cells, Genes & Dev., 22 2008, 2342-2346 (2008).
  10. S. Alonso, D. G. Míguez, F. Sagués, Differential susceptibility to noise of mixed Turing and Hopf modes in a photosensitive chemical medium, Europhys. Lett, 81, 30006 (2008).
  11. D. G. Míguez, V. K. Vanag, I. R. Epstein, Fronts and pulses in an enzymatic reaction with glucose oxidase P.N.A.S. 104, 6992 (2007).
  12. V. K. Vanag, D.G. Míguez, I. R. Epstein, Designing an Enzymatic Oscillator: Bistability and Feedback Control led Oscillations with Glucose Oxidase in a CSTR, J. Phys. Chem. 125, 194515 (2006).
  13. D.G. Míguez, S. Alonso, A.P. Muñuzuri, F. Sagués, Experimental evidence of localized oscillations in the photosensitive chlorine dioxide-iodine-malonic acid reaction, Phys. Rev. Lett, 97, 178301 (2006).
  14. D. G. Míguez, A. P. Muñuzuri, On the orientation of stripes in fish skin patterning, Biophys. Chem. 124, 161 (2006).
  15. D. G. Míguez, R. A. Satnoianu, A. P. Muñuzuri, Experimental steady pattern formation in reaction-diffusion-advection systems, Phys. Rev. E 73, 025201 (R) (2006).
  16. D. G. Míguez, M. Dolnik, A. P. Muñuzuri, L. Kramer, Effect of Axial Growth on Turing Pattern Formation. Phys. Rev. Lett 96, 048304 (2006).
  17. D. G. Míguez, G. Izús, A. P. Muñuzuri, Robustness and Stability of Flow-and-Diffusion Structures, Phys. Rev. E 73, 016207 (2006).
  18. D. G. Miguez, V. Perez-Villar, and A. P. Munuzuri, Turing instability controlled by spatiotemporal imposed dynamics, Phys. Rev. E 71, 066217 (2005).
  19. F. Sagués, D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, L. Kramer, Travelling-stripe forcing of Turing patterns, Physica D 199, 235 (2004).
  20. D. G. Míguez, E. M. Nicola, A. P. Muñuzuri, J. Casademunt, F. Sagués, L. Kramer, Traveling-Stripe Forcing Generates Hexagonal Patterns, Phys. Rev. Lett. 93, 048303 (2004).
  21. M. Kærn, D. G. Míguez, A. P. Muñuzuri, M. Menzinger, Control of chemical pattern formation by a clock-and-wavefront type mechanism, Biophys. Chem. 110, 231 (2004). Shared 1st authorship.
  22. B. Peña, C. Pérez-García, A. Sanz-Anchelergues, D. G. Míguez, A. P. Muñuzuri, Transverse instabilities in chemical Turing patterns of stripes, Phys. Rev. E 68, 056206 (2003).
  23. S. Rüdiger, D. G. Míguez, A. P. Muñuzuri, F. Sagués, J. Casademunt, Dynamics of Turing Patterns under Spatiotemporal Forcing, Phys. Rev. Lett 90, 128301 (2003).
  • David 14:50, 18 June 2013 (EDT)
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