Critical micelle concentration (CMC)
From OpenWetWare
(Difference between revisions)
m |
(detergent table) |
||
| Line 5: | Line 5: | ||
{| {{sorttable}} | {| {{sorttable}} | ||
! style="background:lightgrey"|Detergent | ! style="background:lightgrey"|Detergent | ||
| + | ! style="background:lightgrey"|CMC (%w/v) | ||
! style="background:lightgrey"|CMC (mM) | ! style="background:lightgrey"|CMC (mM) | ||
| - | ! style="background:lightgrey"|MW | + | ! style="background:lightgrey"|MW |
! style="background:lightgrey"|Type | ! style="background:lightgrey"|Type | ||
|- | |- | ||
| - | | BRIJ 35 || 0.09 || | + | | BRIJ 35 || || 0.09 || 1200 || non-ionic |
|- | |- | ||
| - | | NP-40 || 0.05-0.3 || 603 || non-ionic | + | | NP-40 || 0.017 || 0.05-0.3 || 603 || non-ionic |
|- | |- | ||
| - | | [[Triton X-100]] || | + | | [[Triton X-100]] || 0.021 || 0.3 || 650 || non-ionic |
|- | |- | ||
| - | | [[Tween 20]] || 0.059 || | + | | [[Tween 20]] || || 0.059 || 1228 || non-ionic |
|- | |- | ||
| - | | [[SDS]] || 7-10 || 288.5 || ionic | + | | [[SDS]] || 0.23 || 7-10 || 288.5 || ionic |
|- | |- | ||
| - | | CHAPS || 6-10 || | + | | CHAPS || 0.49 || 6-10 || 615 || zwitterionic |
|- | |- | ||
|} | |} | ||
| - | |||
| - | |||
== Sources == | == Sources == | ||
Revision as of 09:44, 28 July 2009
Critical micelle concentration (CMC) is defined as the concentration of detergents above which micelles are spontaneously formed. The CMC is important in biology because at concentrations above it the detergents form complexes with lipophilic proteins. Below this borderline, detergents merely partition into membranes without solubilising membrane proteins.
| Detergent | CMC (%w/v) | CMC (mM) | MW | Type |
|---|---|---|---|---|
| BRIJ 35 | 0.09 | 1200 | non-ionic | |
| NP-40 | 0.017 | 0.05-0.3 | 603 | non-ionic |
| Triton X-100 | 0.021 | 0.3 | 650 | non-ionic |
| Tween 20 | 0.059 | 1228 | non-ionic | |
| SDS | 0.23 | 7-10 | 288.5 | ionic |
| CHAPS | 0.49 | 6-10 | 615 | zwitterionic |
Sources
See also
- [[]]
