Collins Lab

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In the press

  • Nature Methods Research Highlights article on "Network countdown" August 2009 [1]
  • Wall Street Journal article on "Programming cells to do the work" July 2009 [2]
  • Jim Collins' Nature Journal Club article on "A bioengineer gets schooled by E. coli" July 2009 [3]
  • Nature Biotechnology Research Highlights article on "Making cells count" July 2009 [4]
  • Nature Chemical Biology Research Highlights article on "Easy as 1,2,3" July 2009 [5]
  • Jim Collins on BBC's Americana July 2009 [6]
  • Christian Science Monitor article on "Scientists turn living cells into clocks" June 2009 [7]
  • Discovery Channel story on "Bacteria cells programmed to count" June 2009 [8]
  • Science News article on "Engineeered DNA counts it out" May 2009 [9]
  • New Scientist article on "Counting cells could trigger their own destruction" May 2009 [10]
  • Wired Science article on "Cellular counter brings computer programming to life" May 2009 [11]
  • Science Perspective article on "It's the DNA that counts" May 2009 [12]
  • MIT news story on "Engineered circuits can count cellular events" May 2009 [13]
  • Nature Reviews Genetic Research Highlights article on "Towards off-the-shelf networks" May 2009 [14]
  • Nature Biotechnology News & Views article on "Overpowering the component problem" May 2009 [15]
  • Genetic Engineering & Biotechnology News article on "Practical applications of systems biology" May 2009 [16]




Our lab is focused on developing and using nonlinear dynamics approaches to study, mimic and improve the function of biological systems. We are currently working in three areas:

Systems Biology: We are developing and implementing computational-experimental methods to reverse engineer and analyze regulatory networks in microbes and higher organisms.

Synthetic Biology: We are modeling and building synthetic gene networks for a variety of biotechnology and biocomputing applications. We are also using engineered gene networks to study general principles underlying gene regulation.

Our lab is part of the Center for BioDynamics [17], the Department of Biomedical Engineering [18], the Bioinformatics Program, the Center for Advanced Biotechnology, the Molecular Biology, Cell Biology & Biochemistry (MCBB) Program at Boston University, and the Frontiers in Integrative Biological Research.

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