ChemEng575Docs

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(Week 4)
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__NOTOC__
__NOTOC__
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== Week 1 ==
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== Schedule for Semester ==
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'''Reading'''<br>
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Updated 1-26-15<br>
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Tissue Engineering Chapters 1-4<br>
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[[Image:575_Schedule_2015.jpg | 750px]]<br>
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External Reading: Sharp/Langer, Promoting Convergence [http://www.ncbi.nlm.nih.gov/pubmed?term=sharp%20langer%20promoting%20convergence pubmed link]<br>
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External Reading: Huebsch and Mooney, Biomaterials [http://www.ncbi.nlm.nih.gov/pubmed/19940912 pubmed link]<br>
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'''Lecture Slides'''<br>
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== Lecture Slides ==
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[[Media:590B_Lecture_1.pptx |Lecture 1 Slides]]<br>
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[[Media:575_Lecture_1.pptx |Lecture 1 Slides]]<br>
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[[Media:590B_Lecture_2.pptx |Lecture 2 Slides]]<br>
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[[Media:575_Lecture_2.pptx |Lecture 2 Slides]]<br>
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[[Media:575_Lecture_3.pptx |Lecture 3 Slides]]<br>
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[[Media:575_Lecture_4.pptx |Lecture 4 Slides]]<br>
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[[Media:575_Lecture_5.pptx |Lecture 5 Slides]]<br>
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[[Media:575_Lecture_6.pptx |Lecture 6 Slides]]<br>
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[[Media:575_Lecture_7.pptx |Lecture 7 Slides]]<br>
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[[Media:575_Lecture_8.pptx |Lecture 8 Slides]]<br>
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Lecture 9: no new slides (wikis took up entire lecture time)<br>
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[[Media:575_Lecture_10.pptx |Lecture 10 Slides]]<br>
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[[Media:575_Lecture_11.pptx |Lecture 11 Slides]]<br>
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[[Media:575_Lecture_12.pptx |Lecture 12 Slides]]<br>
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== Week 2 ==
 
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'''Reading'''<br>
 
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'''STEM CELLS'''<br>
 
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External Reading: Comprehensive stem cell review [http://www.ncbi.nlm.nih.gov/pubmed/10647940 pubmed link]<br>
 
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'''HSCs'''<br>
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== Readings ==
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External Reading: HSC to hepatocyte differentiation [http://www.ncbi.nlm.nih.gov/pubmed/11062533 pubmed link]<br>
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'''Lecture 1''' 1/20/15<br>
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External Reading: Transplanting HSCs [http://www.ncbi.nlm.nih.gov/pubmed/16641398 pubmed link]<br>
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None
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'''MSCs'''<br>
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'''Lecture 2''' 1/22/15<br>
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External Reading: MSC differentiation potential [http://www.ncbi.nlm.nih.gov/pubmed/10102814 pubmed link]<br>
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None<br>
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External Reading: Engler, MSCs and stiffness [http://www.ncbi.nlm.nih.gov/pubmed/16923388 pubmed link]<br>
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Need help with biology?  Check out MBOC (Alberts) from the library, Great resource.<br>
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'''Lecture Slides'''<br>
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'''Lecture 3''' 1/29/15<br>
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[[Media:590B_Lecture_3.pdf | Lecture 3 Slides]]<br>
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Chapter 2 of the wiki book [[575 Wikis]]
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[[Media:590B_Lecture_4.pptx | Lecture 4 Slides]]<br>
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 +
'''Lecture 4''' 2/3/15<br>
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Paper Review [[Media:Langer1993.pdf | 1993 Intro to Tissue Engineering]]<br>
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== Week 3 ==
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'''Lecture 5''' 2/10/15<br>
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'''Reading'''<br>
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Paper Review [[Media:iPSC_Breakthrough.pdf | The iPSC Breakthrough Paper]]<br>
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Tissue Engineering Chapters 3 & 6<br>
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'''ESCs'''<br>
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'''Lecture 6''' 2/12/15<br>
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External Reading: ESCs from blastocysts [http://www.ncbi.nlm.nih.gov/pubmed/14999088 pubmed link]<br>
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Chapter 3 of the wiki book [[575 Wikis]]
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External Reading: ESCs from blastocysts, 2 [http://www.ncbi.nlm.nih.gov/pubmed/9804556 pubmed link]<br>
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External Reading: Geron's ESC-to-oligodendrocyte [http://www.ncbi.nlm.nih.gov/pubmed/15888645 pubmed link]<br>
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'''iPSCs'''<br>
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'''Lecture 7''' 2/19/15<br>
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External Reading: Seminal iPSC paper [http://www.ncbi.nlm.nih.gov/pubmed/16904174 pubmed link]<br>
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Chapter 4 of the wiki book [[575 Wikis]]
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'''CELL ADHESION'''<br>
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'''Lecture 8''' 2/24/15<br>
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External Reading: Self-assembled monolayers [http://www.ncbi.nlm.nih.gov/pubmed/15005605 pubmed link]<br>
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Paper Review [[Media:McBeath_CellShape.pdf | Cell Shape and Stem Cells]]<br>
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External Reading: adhesion and stem cell differentiation [http://www.ncbi.nlm.nih.gov/pubmed/15068789 pubmed link]<br>
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External Reading: cell size and death [http://www.ncbi.nlm.nih.gov/pubmed/8171320 pubmed link]<br>
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[[Media:590B_Lecture_5.pptx | Lecture 5 Slides]]<br>
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'''Lecture 9''' 2/26/15 <br>
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[[Media:590B_Lecture_6.pptx | Lecture 6 Slides]]<br>
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Chapter 4 of the wiki book [[575 Wikis]]
 +
'''Lecture 10''' 3/10/15 <br>
 +
Paper Review [[Media:Mechanics_StemCells_Review.pdf | Mechanical Regulation of Stem Cells]]<br>
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== Week 4 ==
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'''Lecture 11''' 3/12/15 <br>
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'''Reading'''<br>
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[http://grants.nih.gov/grants/grants_process.htm NIH grants guide]
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Tissue Engineering Chapter 12<br>
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'''Lecture Slides'''<br>
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'''Lecture 12'''<br>
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[[Media:590B_Lecture_7.pptx | Lecture 7 Slides]]<br>
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Paper Review [[Media:FOXN1_Thymus.pdf | Engineered Thymus]]<br>
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''anything below here hasn't been updated for 2013 yet''
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'''Lecture 13'''<br>
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***
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Paper Review [[Media:3D_Injectable_Microniches.pdf | Ischemia and Gels]]<br>
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== Week 8 ==
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'''Lecture 14'''<br>
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Lecture 12, 3/13: <br>
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Grant review day. See your assigned grants at [[ChemEng590BAssignments]]
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Collective cell migration review [http://pubs.rsc.org/en/content/articlelanding/2010/ib/c0ib00052c IBiol link]<br>
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Individual vs collective migration [http://jcb.rupress.org/content/188/1/11.full JCB link]<br>
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== Week 7 ==
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'''Lecture 15'''<br>
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Lecture 11, 3/8: <br>
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Paper Review [[Media:Migration_and_Cytoskeleton.pdf | Review of Cell Cytoskeleton]]<br>
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See your lecture slides!
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== Week 6 ==
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'''Lecture 16'''<br>
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Lecture 8, 2/28: <br>
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TBD
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Patterned RGDs [http://onlinelibrary.wiley.com/doi/10.1002/anie.201002699/abstract Wiley link]<br>
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Engineered surfaces review [http://www.ncbi.nlm.nih.gov/pubmed/19864174 pubmed link]<br>
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biphasic migration [http://www.ncbi.nlm.nih.gov/pubmed/8335696 pubmed link]<br>
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microfluidics [http://www.ncbi.nlm.nih.gov/pubmed/15986641 pubmed link]<br>
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Lecture 9, 3/1: <br>
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'''Lecture 17'''<br>
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first stiffness/migration paper [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1300921/ pubmed link]<br>
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TBD
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gradients and stiffness [http://pubs.acs.org/doi/abs/10.1021/la026403p ACS link]<br>
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biphasic migration and stiffness [http://www.ncbi.nlm.nih.gov/pubmed/15669099 pubmed link]<br>
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3D stiffness in collagen [http://www.ncbi.nlm.nih.gov/pubmed/18621811 pubmed link]<br>
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3D scaffold stiffness [http://www.ncbi.nlm.nih.gov/pubmed/21191996 pubmed link]<br>
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3D matrigel stiffness [http://www.pnas.org/content/103/29/10889 PNAS link]<br>
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== Week 5 ==
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'''Lecture 18'''<br>
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External Reading: Patterning of growth factors [http://www.ncbi.nlm.nih.gov/pubmed/18850272 pubmed link]<br>
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TBD
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External Reading: Modeling Interstitial flow [http://www.ncbi.nlm.nih.gov/pubmed/16603487 pubmed link]<br>
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External Reading: Chemotaxis assays review [http://www.ncbi.nlm.nih.gov/pubmed/20023801 pubmed link]<br>
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'''Lecture 19'''<br>
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External Reading: Chemotaxis and directed migration [http://www.ncbi.nlm.nih.gov/pubmed/19603038 pubmed link]<br>
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TBD
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'''Lecture 20'''<br>
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TBD

Current revision

      Home                 Documents               Assignments               Wiki Schedule                 Wiki Pages                 Course Syllabus


Schedule for Semester

Updated 1-26-15

Lecture Slides

Lecture 1 Slides
Lecture 2 Slides
Lecture 3 Slides
Lecture 4 Slides
Lecture 5 Slides
Lecture 6 Slides
Lecture 7 Slides
Lecture 8 Slides
Lecture 9: no new slides (wikis took up entire lecture time)
Lecture 10 Slides
Lecture 11 Slides
Lecture 12 Slides


Readings

Lecture 1 1/20/15
None

Lecture 2 1/22/15
None
Need help with biology? Check out MBOC (Alberts) from the library, Great resource.

Lecture 3 1/29/15
Chapter 2 of the wiki book 575 Wikis

Lecture 4 2/3/15
Paper Review 1993 Intro to Tissue Engineering

Lecture 5 2/10/15
Paper Review The iPSC Breakthrough Paper

Lecture 6 2/12/15
Chapter 3 of the wiki book 575 Wikis

Lecture 7 2/19/15
Chapter 4 of the wiki book 575 Wikis

Lecture 8 2/24/15
Paper Review Cell Shape and Stem Cells

Lecture 9 2/26/15
Chapter 4 of the wiki book 575 Wikis

Lecture 10 3/10/15
Paper Review Mechanical Regulation of Stem Cells

Lecture 11 3/12/15
NIH grants guide

Lecture 12
Paper Review Engineered Thymus

Lecture 13
Paper Review Ischemia and Gels

Lecture 14
Grant review day. See your assigned grants at ChemEng590BAssignments

Lecture 15
Paper Review Review of Cell Cytoskeleton

Lecture 16
TBD

Lecture 17
TBD

Lecture 18
TBD

Lecture 19
TBD

Lecture 20

TBD
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