ChemEng575Docs

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__NOTOC__
__NOTOC__
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== Week 1 ==
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== Lecture Slides ==
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Tissue Engineering Chapters 1-4
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[[Media:575_Lecture_1.pptx |Lecture 1 Slides]]<br>
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External Reading: Sharp/Langer, Promoting Convergence [http://www.ncbi.nlm.nih.gov/pubmed?term=sharp%20langer%20promoting%20convergence pubmed link]<br>
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[[Media:575_Lecture_2.pptx |Lecture 2 Slides]]<br>
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External Reading: Huebsch and Mooney, Biomaterials [http://www.ncbi.nlm.nih.gov/pubmed/19940912 pubmed link]<br>
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[[Media:575_Lecture_3.pptx |Lecture 3 Slides]]<br>
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[[Media:575_Lecture_4.pptx |Lecture 4 Slides]]<br>
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[[Media:575_Lecture_5.pptx |Lecture 5 Slides]]<br>
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[[Media:575_Lecture_6.pptx | Lecture 6 Slides]]<br>
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[[Media:575_Lecture_7.pdf | Lecture 7 Slides]]<br>
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Lecture 8: no slides (all on chalkboard)<br>
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[[Media:575_Lecture_9.pptx |Lecture 9 Slides]]<br>
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[[Media:575_Lecture_10.pptx |Lecture 10 Slides]]<br>
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Lecture 11: no slides (Grant Review day)<br>
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[[Media:575_Lecture_12.pptx |Lecture 12 Slides]]<br>
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[[Media:575_Lecture_13.pptx |Lecture 13 Slides]]<br>
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[[Media:575_Lecture_15.pptx |Lecture 14 Slides]]<br>
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[[Media:575_Lecture_14.pptx |Lecture 15 Slides]]<br>
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[[Media:575_Lecture_17.pptx |Lecture 17 Slides]]<br>
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== Readings ==
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'''Lecture 1'''<br>
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Sharp/Langer, Promoting Convergence [http://www.ncbi.nlm.nih.gov/pubmed?term=sharp%20langer%20promoting%20convergence pubmed link]<br>
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'''Lecture 2'''<br>
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None required.  MBOC is a good textbook if you need a biology refresher<br>
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''anything below here hasn't been updated for 2013 yet''
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'''Lecture 3'''<br>
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***
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None required.  Again, check MBOC if the lecture was tough.
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== Week 8 ==
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'''Lecture 4'''<br>
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Lecture 12, 3/13: <br>
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External Reading: Engler, MSCs and stiffness [http://www.ncbi.nlm.nih.gov/pubmed/16923388 pubmed link]<br>
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Collective cell migration review [http://pubs.rsc.org/en/content/articlelanding/2010/ib/c0ib00052c IBiol link]<br>
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External Reading: Transplanting HSCs [http://www.ncbi.nlm.nih.gov/pubmed/16641398 pubmed link]<br>
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Individual vs collective migration [http://jcb.rupress.org/content/188/1/11.full JCB link]<br>
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Wiki Reading: [http://openwetware.org/wiki/Bone_Marrow_Transplants%2C_by_Erinn_Dandley_and_Max_Nowak WikiLink]<br>
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== Week 7 ==
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'''Lecture 5'''<br>
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Lecture 11, 3/8: <br>
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External Reading: Comprehensive stem cell review [http://www.ncbi.nlm.nih.gov/pubmed/10647940 pubmed link]<br>
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See your lecture slides!
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External Reading: Seminal iPSC paper [http://www.ncbi.nlm.nih.gov/pubmed/16904174 pubmed link]<br>
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External Reading: Geron's ESC-to-oligodendrocyte [http://www.ncbi.nlm.nih.gov/pubmed/15888645 pubmed link]<br>
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External Reading: ESCs from blastocysts [http://www.ncbi.nlm.nih.gov/pubmed/14999088 pubmed link]<br>
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Wiki Reading: [http://openwetware.org/wiki/CellEct_Bio_%28Stem_Cell_Therapy%29%2C_by_Dan_Ganz WikiLink]<br>
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== Week 6 ==
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'''Lecture 6'''<br>
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Lecture 8, 2/28: <br>
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PDF of other reading available upon request<br>
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Patterned RGDs [http://onlinelibrary.wiley.com/doi/10.1002/anie.201002699/abstract Wiley link]<br>
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External Reading: adhesion and stem cell differentiation [http://www.ncbi.nlm.nih.gov/pubmed/15068789 pubmed link]<br>
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Engineered surfaces review [http://www.ncbi.nlm.nih.gov/pubmed/19864174 pubmed link]<br>
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biphasic migration [http://www.ncbi.nlm.nih.gov/pubmed/8335696 pubmed link]<br>
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microfluidics [http://www.ncbi.nlm.nih.gov/pubmed/15986641 pubmed link]<br>
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Lecture 9, 3/1: <br>
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'''Lecture 7'''<br>
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first stiffness/migration paper [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1300921/ pubmed link]<br>
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External Reading: Huebsch and Mooney, Biomaterials [http://www.ncbi.nlm.nih.gov/pubmed/19940912 pubmed link]<br>
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gradients and stiffness [http://pubs.acs.org/doi/abs/10.1021/la026403p ACS link]<br>
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biphasic migration and stiffness [http://www.ncbi.nlm.nih.gov/pubmed/15669099 pubmed link]<br>
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3D stiffness in collagen [http://www.ncbi.nlm.nih.gov/pubmed/18621811 pubmed link]<br>
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3D scaffold stiffness [http://www.ncbi.nlm.nih.gov/pubmed/21191996 pubmed link]<br>
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3D matrigel stiffness [http://www.pnas.org/content/103/29/10889 PNAS link]<br>
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== Week 5 ==
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'''Lecture 8'''<br>
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External Reading: Patterning of growth factors [http://www.ncbi.nlm.nih.gov/pubmed/18850272 pubmed link]<br>
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PDF of other reading available upon request<br>
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External Reading: Modeling Interstitial flow [http://www.ncbi.nlm.nih.gov/pubmed/16603487 pubmed link]<br>
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External Reading: Chemotaxis assays review [http://www.ncbi.nlm.nih.gov/pubmed/20023801 pubmed link]<br>
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External Reading: Chemotaxis and directed migration [http://www.ncbi.nlm.nih.gov/pubmed/19603038 pubmed link]<br>
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== Week 4 ==
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'''Lecture 9'''<br>
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External Reading: All are ECM and cancer
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PDF of other reading available upon request<br>
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1: [http://www.ncbi.nlm.nih.gov/pubmed/19931152 pubmed link]<br>
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Wiki Reading: [http://openwetware.org/wiki/Vascularization%2C_by_Brittany_Forkus WikiLink]<br>
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2: [http://www.ncbi.nlm.nih.gov/pubmed/16169468 pubmed link]<br>
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3: [http://www.ncbi.nlm.nih.gov/pubmed/17190588 pubmed link]<br>
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== Week 3 ==
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'''Lecture 10'''<br>
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'''CELL ADHESION'''<br>
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NIH grant guidelines page [http://grants.nih.gov/grants/funding/424/index.htm NIH link]<br>
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External Reading: Self-assembled monolayers [http://www.ncbi.nlm.nih.gov/pubmed/15005605 pubmed link]<br>
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External Reading: adhesion and stem cell differentiation [http://www.ncbi.nlm.nih.gov/pubmed/15068789 pubmed link]<br>
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External Reading: cell size and death [http://www.ncbi.nlm.nih.gov/pubmed/8171320 pubmed link]<br>
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== Week 2 ==
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'''Lecture 11'''<br>
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'''STEM CELLS'''<br>
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Grant review day.  Your reading is the grants you've been assigned: [[ChemEng590BAssignments | Assignments Page]]<br>
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External Reading: Comprehensive stem cell review [http://www.ncbi.nlm.nih.gov/pubmed/10647940 pubmed link]<br>
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'''MSCs'''<br>
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'''Lecture 12'''<br>
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External Reading: MSC differentiation potential [http://www.ncbi.nlm.nih.gov/pubmed/10102814 pubmed link]<br>
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PDF of other reading available upon request<br>
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External Reading: Engler, MSCs and stiffness [http://www.ncbi.nlm.nih.gov/pubmed/16923388 pubmed link]<br>
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Haptokinesis, migration [http://www.ncbi.nlm.nih.gov/pubmed/8335696 pubmed link]<br>
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'''ESCs'''<br>
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'''Lecture 13'''<br>
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External Reading: ESCs from blastocysts [http://www.ncbi.nlm.nih.gov/pubmed/14999088 pubmed link]<br>
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External Reading: Modeling Interstitial flow [http://www.ncbi.nlm.nih.gov/pubmed/16603487 pubmed link]<br>
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External Reading: ESCs from blastocysts, 2 [http://www.ncbi.nlm.nih.gov/pubmed/9804556 pubmed link]<br>
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External Reading: Geron's ESC-to-oligodendrocyte [http://www.ncbi.nlm.nih.gov/pubmed/15888645 pubmed link]<br>
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'''HSCs'''<br>
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'''Lecture 14'''<br>
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External Reading: HSC to hepatocyte differentiation [http://www.ncbi.nlm.nih.gov/pubmed/11062533 pubmed link]<br>
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Nature Outlook on Enhanced Medical Vision [http://www.nature.com/nature/journal/v502/n7473_supp/full/502S82a.html Nature link]<br>
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External Reading: Transplanting HSCs [http://www.ncbi.nlm.nih.gov/pubmed/16641398 pubmed link]<br>
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Nature Outlook on Alzheimer's [http://www.nature.com/nature/journal/v502/n7473_supp/full/502S84a.html Nature link]<br>
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Nature Outlook on Tomography [http://www.nature.com/nature/journal/v502/n7473_supp/full/502S90a.html Nature link]<br>
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Nature Outlook on Computer Aided Imaging [http://www.nature.com/nature/journal/v502/n7473_supp/full/502S92a.html Nature link]<br>
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Nature Outlook on Image Storing [http://www.nature.com/nature/journal/v502/n7473_supp/full/502S95a.html Nature link]<br>
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'''iPSCs'''<br>
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'''Lecture 15'''<br>
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External Reading: Seminal iPSC paper [http://www.ncbi.nlm.nih.gov/pubmed/16904174 pubmed link]<br>
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first stiffness/migration paper [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1300921/ pubmed link]<br>
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Durotaxis (2D Gradients) [http://pubs.acs.org/doi/abs/10.1021/la026403p ACS link]<br>
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Biphasic Durokinesis [http://www.ncbi.nlm.nih.gov/pubmed/15669099 pubmed link]<br>

Current revision

      Home                 Documents               Assignments               Wiki Schedule                 Wiki Pages                 Course Syllabus


Lecture Slides

Lecture 1 Slides
Lecture 2 Slides
Lecture 3 Slides
Lecture 4 Slides
Lecture 5 Slides
Lecture 6 Slides
Lecture 7 Slides
Lecture 8: no slides (all on chalkboard)
Lecture 9 Slides
Lecture 10 Slides
Lecture 11: no slides (Grant Review day)
Lecture 12 Slides
Lecture 13 Slides
Lecture 14 Slides
Lecture 15 Slides
Lecture 17 Slides

Readings

Lecture 1
Sharp/Langer, Promoting Convergence pubmed link

Lecture 2
None required. MBOC is a good textbook if you need a biology refresher

Lecture 3
None required. Again, check MBOC if the lecture was tough.

Lecture 4
External Reading: Engler, MSCs and stiffness pubmed link
External Reading: Transplanting HSCs pubmed link
Wiki Reading: WikiLink

Lecture 5
External Reading: Comprehensive stem cell review pubmed link
External Reading: Seminal iPSC paper pubmed link
External Reading: Geron's ESC-to-oligodendrocyte pubmed link
External Reading: ESCs from blastocysts pubmed link
Wiki Reading: WikiLink

Lecture 6
PDF of other reading available upon request
External Reading: adhesion and stem cell differentiation pubmed link

Lecture 7
External Reading: Huebsch and Mooney, Biomaterials pubmed link

Lecture 8
PDF of other reading available upon request

Lecture 9
PDF of other reading available upon request
Wiki Reading: WikiLink

Lecture 10
NIH grant guidelines page NIH link

Lecture 11
Grant review day. Your reading is the grants you've been assigned: Assignments Page

Lecture 12
PDF of other reading available upon request
Haptokinesis, migration pubmed link

Lecture 13
External Reading: Modeling Interstitial flow pubmed link

Lecture 14
Nature Outlook on Enhanced Medical Vision Nature link
Nature Outlook on Alzheimer's Nature link
Nature Outlook on Tomography Nature link
Nature Outlook on Computer Aided Imaging Nature link
Nature Outlook on Image Storing Nature link

Lecture 15
first stiffness/migration paper pubmed link
Durotaxis (2D Gradients) ACS link

Biphasic Durokinesis pubmed link
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