Our lab is interested in transposons using an approach combining biochemistry, cell biology, bioinformatics and mathematical modelling.
Our current projects are:
- To determine the mechanism of mariner transposition
- To find the functions of a primate-specific domesticated transposase
- To develop mariner transposons as gene vectors
Claeys Bouuaert C, Chalmers R. Hsmar1 Transposition Is Sensitive to the Topology of the Transposon Donor and the Target. PLoS ONE. 2013 Jan 14;8(1): e53690.