CH391L/S13/Optogenetics

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#Lalumiere2011 pmid=21255749
#Lalumiere2011 pmid=21255749
#Doroudchi2011 pmid=21505421
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#Boyden2005 pmid=16116447
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Revision as of 01:02, 25 February 2013

Contents

Introduction to Optogenetics

"Before we can find the answers, we need the power to ask new questions." -Karl Deisseroth

History

"The brain is a world consisting of a number of unexplored continents and great stretches of unknown territory." - Santiago Ramón y Cajal

Biochemistry behind Optogenetics

The Optogenetic Process

Gene Delivery

Controlled Illumination

Applications of Optogenetics

Neuroscience

Cardiology: Pacemakers

Hepatology: Diabetes and Beta Cells

IGEM Take-home Message

http://2012.igem.org/Team:Washington/Optogenetics http://2006.igem.org/wiki/index.php/University_of_Texas_2006 http://2006.igem.org/wiki/index.php/UT_Austin_2005 http://2004.igem.org/austin.cgi

References

  1. Mei Y and Zhang F. . pmid:22480664. PubMed HubMed [Mei2012]
  2. Yizhar O, Fenno L, Zhang F, Hegemann P, and Diesseroth K. . pmid:21363959. PubMed HubMed [Yizhar2011]
  3. Zemelman BV, Lee GA, Ng M, and Miesenböck G. . pmid:11779476. PubMed HubMed [Zemelman2002]
  4. LaLumiere RT. . pmid:21255749. PubMed HubMed [Lalumiere2011]
  5. Doroudchi MM, Greenberg KP, Liu J, Silka KA, Boyden ES, Lockridge JA, Arman AC, Janani R, Boye SE, Boye SL, Gordon GM, Matteo BC, Sampath AP, Hauswirth WW, and Horsager A. . pmid:21505421. PubMed HubMed [Doroudchi2011]
  6. Boyden ES, Zhang F, Bamberg E, Nagel G, and Deisseroth K. . pmid:16116447. PubMed HubMed [Boyden2005]
All Medline abstracts: PubMed HubMed
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