CH391L/S13/Optogenetics: Difference between revisions
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Revision as of 21:10, 24 February 2013
Introduction to Optogenetics
"Before we can find the answers, we need the power to ask new questions." -Karl Deisseroth
History
"The brain is a world consisting of a number of unexplored continents and great stretches of unknown territory." - Santiago Ramón y Cajal
Biochemistry behind Optogenetics
The Optogenetic Process
Gene Delivery
Controlled Illumination
Applications of Optogenetics
Neuroscience
Cardiology: Pacemakers
Hepatology: Diabetes and Beta Cells
IGEM Take-home Message
http://2012.igem.org/Team:Washington/Optogenetics http://2006.igem.org/wiki/index.php/University_of_Texas_2006 http://2006.igem.org/wiki/index.php/UT_Austin_2005 http://2004.igem.org/austin.cgi
References
- Mei Y and Zhang F. Molecular tools and approaches for optogenetics. Biol Psychiatry. 2012 Jun 15;71(12):1033-8. DOI:10.1016/j.biopsych.2012.02.019 |
- Yizhar O, Fenno L, Zhang F, Hegemann P, and Diesseroth K. Microbial opsins: a family of single-component tools for optical control of neural activity. Cold Spring Harb Protoc. 2011 Mar 1;2011(3):top102. DOI:10.1101/pdb.top102 |
- Zemelman BV, Lee GA, Ng M, and Miesenböck G. Selective photostimulation of genetically chARGed neurons. Neuron. 2002 Jan 3;33(1):15-22. DOI:10.1016/s0896-6273(01)00574-8 |
