Biomod/2014/UCR/Breaking RNA

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Breaking RNA

EDIT

Content

A Synthetic Oscillatory System using Enzyme Aptamers

In this topology, E1 and E2 are enzymes, while R1,R2,R3, and R4 represent RNA strands. Our aim is to develop an oscillatory system, where E1 would inhibit E2, and E2 would activate E1. The negative feedback loop of E1 is essential for the current model to oscillate, while the positive feedback loop may serve to improve the oscillations observed.

The Model

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