Biomod/2014/NTU: Difference between revisions

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<h3>Abstract</h3>
<h3 id="abstracttitle">Abstract</h3>
<p>Minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum. </p>
<p id="abstract">The immune system is not fail-safe and sometimes requires a booster during an infection. Here we design a versatile jellyfish-like device/nano-robot that is able to enhance the immune system. We have chosen the hemagglutinin type 5 protein (H5) of influenza virus as our target because current treatment faces problems of drug resistance and lengthy vaccine production. The device, initially a ball-shaped dimer, contains two types of tentacles, one being H5 aptamer, and the other being either poly-cytosine (poly-C) or poly-guanine (poly-G) sequences. Upon binding H5, the dimer dissociates, releasing the packaged immuno-stimulatory molecule and exposing poly-C and poly-G. Binding between poly-C and poly-G allows aggregation of the virus-bound monomer. The device/nano-robot is versatile since targets could be modified by changing the attached aptamers. It could potentially provide better treatment for diseases such as HIV/AIDS and malaria, as well as enhance experimental techniques such as bioassays and protein purification. </p>
<p>Auae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt.</p>
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Revision as of 07:45, 19 October 2014

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