Biomod/2014/NTU: Difference between revisions

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<h1>NANOJELLYFISH</h1>
<p>We are NTUBIOMOD</span></p>
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<h3 id="abstracttitle">Abstract</h3>
<p id="abstract">The immune system is not fail-safe and sometimes requires a booster during an infection. Here we design a versatile jellyfish-like device/nano-robot that is able to enhance the immune system. We have chosen the hemagglutinin type 5 protein (H5) of influenza virus as our target because current treatment faces problems of drug resistance and lengthy vaccine production. The device, initially a ball-shaped dimer, contains two types of tentacles, one being H5 aptamer, and the other being either poly-cytosine (poly-C) or poly-guanine (poly-G) sequences. Upon binding H5, the dimer dissociates, releasing the packaged immuno-stimulatory molecule and exposing poly-C and poly-G. Binding between poly-C and poly-G allows aggregation of the virus-bound monomer. The device/nano-robot is versatile since targets could be modified by changing the attached aptamers. It could potentially provide better treatment for diseases such as HIV/AIDS and malaria, as well as enhance experimental techniques such as bioassays and protein purification. </p>
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Revision as of 05:59, 19 October 2014

<!DOCTYPE HTML> <html> <head> <title>Moonlight Website Template | Home :: w3layouts</title> <link href="css/bootstrap.css" rel='stylesheet' type='text/css' /> <!-- jQuery (necessary for Bootstrap's JavaScript plugins) --> <script src="js/jquery.min.js"></script> <!-- Custom Theme files --> <link href="css/style.css" rel='stylesheet' type='text/css' /> 

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<meta name="viewport" content="width=device-width, initial-scale=1"> <script type="application/x-javascript"> addEventListener("load", function() { setTimeout(hideURLbar, 0); }, false); function hideURLbar(){ window.scrollTo(0,1); } </script> </script> <!---- animated-css ----> <link href="css/animate.css" rel="stylesheet" type="text/css" media="all"> <script src="js/wow.min.js"></script> <script> new WOW().init(); </script> <!---- animated-css ----> <!---- start-smoth-scrolling----> <script type="text/javascript" src="js/move-top.js"></script> <script type="text/javascript" src="js/easing.js"></script> <script type="text/javascript"> jQuery(document).ready(function($) { $(".scroll").click(function(event){ event.preventDefault(); $('html,body').animate({scrollTop:$(this.hash).offset().top},1000); }); }); </script> <!---- start-smoth-scrolling----> <!----webfonts---> <link href='http://fonts.googleapis.com/css?family=Lato:100,300,400,700,900,100italic,300italic,400italic,700italic,900italic' rel='stylesheet' type='text/css'> <!---//webfonts---> </head> <body> <!---- container ----> <!---- header ----> <div class="header"> <div class="container"> <!--- beanner-info----> <div class="banner-info text-center wow fadeIn" data-wow-delay="0.5s"> <h1>NANOJELLYFISH</h1> <p>We are NTUBIOMOD</span></p> <a class="play-icon popup-with-zoom-anim" href="#small-dialog"><span> </span></a><br /> </div> <!--- beanner-info----> <!---- video ----> <!---pop-up-box----> <script type="text/javascript" src="js/modernizr.custom.min.js"></script> <link href="css/popuo-box.css" rel="stylesheet" type="text/css" media="all"/> <script src="js/jquery.magnific-popup.js" type="text/javascript"></script> <div id="small-dialog" class="mfp-hide"> <iframe src="//player.vimeo.com/video/38584262" frameborder="0" webkitallowfullscreen mozallowfullscreen allowfullscreen> </iframe> </div> <script> $(document).ready(function() { $('.popup-with-zoom-anim').magnificPopup({ type: 'inline', fixedContentPos: false, fixedBgPos: true, overflowY: 'auto', closeBtnInside: true, preloader: false, midClick: true, removalDelay: 300, mainClass: 'my-mfp-zoom-in' });

}); </script> </div> <!----//fea-video----> </div> </div> <!---- header ----> <!---- content ----> <div class="content"> <div class="top-grids"> <div class="col-md-7 top-left-grid wow fadeInLeft" data-wow-delay="0.4s"> <h3 id="abstracttitle">Abstract</h3> <p id="abstract">The immune system is not fail-safe and sometimes requires a booster during an infection. Here we design a versatile jellyfish-like device/nano-robot that is able to enhance the immune system. We have chosen the hemagglutinin type 5 protein (H5) of influenza virus as our target because current treatment faces problems of drug resistance and lengthy vaccine production. The device, initially a ball-shaped dimer, contains two types of tentacles, one being H5 aptamer, and the other being either poly-cytosine (poly-C) or poly-guanine (poly-G) sequences. Upon binding H5, the dimer dissociates, releasing the packaged immuno-stimulatory molecule and exposing poly-C and poly-G. Binding between poly-C and poly-G allows aggregation of the virus-bound monomer. The device/nano-robot is versatile since targets could be modified by changing the attached aptamers. It could potentially provide better treatment for diseases such as HIV/AIDS and malaria, as well as enhance experimental techniques such as bioassays and protein purification. </p> </div> <div class="col-md-5 top-right-grid wow fadeInRight" data-wow-delay="0.4s"> </div> <div class="clearfix"> </div> </div> <script type="text/javascript"> $(document).ready(function() { $("#test1").hover(function(){ $("#testslide1").animate({left: '+0px'},500);}, function(){ $("#testslide1").animate({left: '-300px'},500);}); $("#test1").hover(function(){ $("#testslide11").animate({left: '+0px'},500);}, function(){ $("#testslide11").animate({left: '-300px'},500);});

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