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<ul id="menu"> <font face="Frutiger,Helvetica,Arial"> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa"><img src="http://openwetware.org/images/e/ec/LogoKashiwa.png" onmouseover="this.src='http://openwetware.org/images/7/7a/Logo2Kashiwa.png'" onclick="this.src='http://openwetware.org/images/1/1d/Logo2.5.png'" onmouseout="this.src='http://openwetware.org/images/e/ec/LogoKashiwa.png'" height="80px" width="120px" name="def"></a> </li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Project" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">PROJECT</span></a> <ul class="sub"> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Project#1" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">Background</span></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Project#2" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">Motivation</span></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Project#3" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">Project Goals</span></a></li> </ul> </li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Trial" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;"> EARLY TRIAL </span></a> <ul class="sub"> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Trial#1" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">Design</span></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Trial#2" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">Approaches</span></a></li> </ul> </li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Design" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">DESIGN</span></a> <ul class="sub"> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Design#2" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">The Receptor</span></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Design#1" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">The Motor</span></a></li> </ul> </li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Highlights" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;"> EXPERIMENT </span></a> <ul class="sub"> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Highlights" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">Highlights</span></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Receptor" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">The Receptor</span></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Motor" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">The Motor</span></a></li> </ul> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Discussion" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;"> DISCUSSION </span></a> <ul class="sub"> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Discussion#1" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">Achievements</span></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Discussion#2" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">Future</span></a></li> </ul> </li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Protocols" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">PROTOCOL</span></a> </li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Team" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">TEAM</span></a> <ul class="sub"> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Team#1" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">Members</span></a></li> <li><a href="http://openwetware.org/wiki/Biomod/2014/Kashiwa/Team#2" onMouseOver="On('img1')" onMouseOut="Off()"><span style="font-size:12pt;">Sponsors</span></a></li> </ul> </li> </font> </ul>
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<body> <a name="1"></a> <font face="Futura,Arial,Frutiger" font size="24px">EXPERIMENTS</font> <br> <br>
<TABLE BORDER="0" WIDTH="100%" CELLSPACING="0" CELLPADDING="30"> <TR> <TD BGCOLOR="#A9A9F5"> <span style="font-size:50px; color:#0A0A2A;">The Receptor</span> </TD> </TR> </TABLE> <h1 class="title"><a name="background"> Direction</a></h1> <p class="paragraph">We planned to do experiments in several steps. First, we design the Receptor. Then, the following experiments are conducted in parallel. </p> <ul type="circle"> <li>Form the Receptor dimer by using thrombin.</li> <li>Emit the Polymerization Initiator by demerization.</li> <li> Penetrate the liposome with the Receptor.</li> </ul> <p class="paragraph">Finally, after success in the experiments, we combine them to attain the dimerization and the Initiator emission on the liposome.</li> </p> <br> <h1 class="title"><a name="background"> Experiments</a></h1> <h1 class="big">Folding the Receptor</h1> <br>
<br> <h1 class="big">Forming the Receptor dimer</h1> <br>
<br> <h1 class="big">Emitting the Initiator</h1> <br>
<br> <h1 class="big">Penetrating the liposome</h1> <br> <h1 class="title"><a name="background"> Next Steps</a></h1>
<br> <br> <TABLE BORDER="0" WIDTH="900px" CELLSPACING="0" CELLPADDING="30" > <TR> <TD BGCOLOR="#A9A9F5"> <span style="font-size:50px; color:#0A0A2A;">The Motor Monomer</span> </TD> </TR> </TABLE> <br> <h1 class="title"><a name="background"> Direction</a></h1> <br> <p class="paragraph">We planned to do experiments in several steps. First, we design the Motor-Monomer and assay the formation of a simple Motor-Polymer. Then, the following experiments are conducted in parallel.</p> <ul> <li>Control the initiation of the polymerization (forming ring structures and ring-opening polymerization).</li> <li>Put the Motor-Monomers into the liposome.</li> </ul> <p class="paragraph">Finally, after success in the experiments, we combine them to attain the polymerization in the liposome.</p> <br>
<h1 class="title"><a name="background"> Experiments</a></h1> <h1 class="big">Folding the Motor-Monomer</h1> <br>
<br> <h1 class="big">Forming the Motor-Polymer</h1> <br>
<br> <h1 class="big">Controlling the initiation</h1> <h1 class="small"> (a)Forming ring structures</h1> <br> <h1 class="small"> (b)Opening ring structures</h1> <br>
<br> <h1 class="big">Putting into the liposome</h1> <br> <br> <h1 class="title"><a name="background"> Next Steps</a></h1> <br>
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