Biomod/2013/StJohns

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DNA-based nanotechnology utilizes the exquisite selectivity of the Watson-Crick base-pair, combined with deep understanding and control of double-helical structure gleaned from physics, molecular biology, chemistry and nanotechnology, to program the self-assembly of nanometer-scale objects.


The goal of this project is the creation of a DNA origami structure that undergoes significant conformational changes when bound to objects ranging in size from 10-100 nm. Since binding-specific conformational change can be transduced into a signal, this should enable the design of robust sensors for a wide variety of nano-scale objects, such as viruses.

We especially wish to acknowledge




We are team Toehold Conga Nanny.

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