Biomod/2013/NanoUANL/Reactor

What is a reactor?

Introduction

The CCMV capsid was considered as a continuous stirred-tank reactor with accumulation of the product.

For an enzymatic reaction of the type:

[math]\displaystyle{ E + S \leftrightarrow ES \rightarrow E^0 + P }[/math]

with a reaction rate of:

[math]\displaystyle{ \frac{d[ES]}{dt}=k_1[E][S]-k_{-1}[ES]-k_2[ES] }[/math]

We established the following in our system:

• Uniform distribution throughout the reactor
• K_-1 >> K₁ and K₂
• One enzyme per reactor/VLP
• Tortuosity approaches zero during diffusion

Mass balance was presented as such:

INPUT = OUTPUT - DISAPPEARANCE BY REACTION + ACCUMULATION

where

Input = F₀ Output = F₀(1-X_S) Disappearance = V(-r_S Accumulation = [math]\displaystyle{ \tfrac{d[P]}{dt} }[/math]