What is a reactor?
The CCMV capsid was considered as a continuous stirred-tank reactor with accumulation of the product.
For an enzymatic reaction of the type:
with a reaction rate of:
We established the following in our system:
- Uniform distribution throughout the reactor
- K-1 >> K1 and K2
- One enzyme per reactor/VLP
- Tortuosity approaches zero during diffusion
Mass balance was presented as such:
INPUT = OUTPUT - DISAPPEARANCE BY REACTION + ACCUMULATION
Input = F0 Output = F0(1-XS) Disappearance = V(-rS Accumulation =