Biomod/2012/UTokyo/UT-Komaba/Progress: Difference between revisions

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[[Image:BIOMOD-2012-UTkyo-UTKomaba-AFM-0920-origami15×withenzymes.png|300px|thumb|AFM image of origami with enzymes]]
[[Image:BIOMOD-2012-UTkyo-UTKomaba-AFM-0920-origami15×withenzymes.png|300px|thumb|AFM image of origami with enzymes]]


We confirmed that DNA origami structures weren't destroyed by environment of the bistable system.
We confirmed that DNA origami structures weren't destroyed by the environment of the bistable system.
 


===Modified DNA Origami===
===Modified DNA Origami===

Revision as of 23:34, 26 October 2012

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<div id="title"><img src="http://openwetware.org/images/4/47/Biomod_2012_UTokyo_UT-Komaba_Top.png" alt="DNA tablet" width="800" height="120" onClick="this.src='http://openwetware.org/images/7/7d/BIOMOD_2012_UTokyo_UT-Komaba_title-animation.gif'"/></div>

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 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba">Home</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Idea">Idea</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Simulation">Simulation</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Experiment">Experiment</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Progress">Progress</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Episode">Episode</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Team">Team</a></li>
 <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Supplementary">Supplementary</a></li>

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Goals And Achievement

DNA Origami

Original DNA Origami

AFM image of origami with BSA
AFM image of origami with enzymes

We confirmed that DNA origami structures weren't destroyed by the environment of the bistable system.

Modified DNA Origami

AFM image of modified Origami

AFM confirmed that the modified Origami with covers worked well (you can see lines in the Origami

Bistable System

the result of bistable system experiment

This graph shows the status of the bistable system with time. In this graph, we tried to switch the state twice. As you can see, the first trial succeeded in reversing the concentration of X and V, changing the state. However, the second trial failed. We need to do more experiments to solve this problem.

DNA Tablet

We designed the DNA tablet and observed the two pictures, "I love DNA", "Tablet Boy".

Design of DNA tablet
Design of DNA tablet

Without Imputs(plain DNA tablet):

I love DNA:

However the image is not clear, but we're sure that there is "I", the love heart, the ring of "D", and a part of the shape of "A".

Tablet Boy:

We have to say again the image is not clear, though, we can see the square and some shapes of the parts of Tablet boy's body.

Conclusion

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