Biomod/2012/UTokyo/UT-Komaba: Difference between revisions
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==Introduction== | ==Introduction== | ||
DNA is used as in information storage molecule and one of its most significant characteristic is stability. | |||
Previously, many DNA | Previously, many DNA nanostructures have been designed that make use of this stability. | ||
Although | Although stability is a merit of DNA, many functions requires a form of variability of the device that perform them. | ||
UT-Komaba team tries to | |||
UT-Komaba team tries to illustrate the potentials of this approach by designing the DNA tablet, the smallest tablet PC on earth. | |||
==Abstract== | ==Abstract== |
Revision as of 06:13, 23 October 2012
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<div id="title"><img src="http://openwetware.org/images/4/47/Biomod_2012_UTokyo_UT-Komaba_Top.png" alt="DNA tablet" width="800" height="120" onClick="this.src='http://openwetware.org/images/7/7d/BIOMOD_2012_UTokyo_UT-Komaba_title-animation.gif'"/></div>
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<li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba">Home</a></li> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Idea">Idea</a></li> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Simulation">Simulation</a></li> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Experiment">Experiment</a></li> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Progress">Progress</a></li> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Episode">Episode</a></li> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Team">Team</a></li> <li><a href="/wiki/Biomod/2012/UTokyo/UT-Komaba/Supplementary">Supplementary</a></li>
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Introduction
DNA is used as in information storage molecule and one of its most significant characteristic is stability. Previously, many DNA nanostructures have been designed that make use of this stability. Although stability is a merit of DNA, many functions requires a form of variability of the device that perform them.
UT-Komaba team tries to illustrate the potentials of this approach by designing the DNA tablet, the smallest tablet PC on earth.
Abstract
Inspired by tablet computers, we propose a DNA origami (tablet) that can display alternative pictures or show a short molecular movie. Our approach combines DNA nanotechnology and DNA dynamic circuits. To demonstrate the unveiling of different images, we created a DNA origami with two latent designs and connected it with a dynamic network having two stables states. This bistability ensures that only one of the two images is displayed at a time, and no intermediate erroneous displays are produced.
The user can browse his library of images, by introducing a small amount of an image-specific tag sequence to switch the bistable system. The size of the library, currently two, could be extended by using a n-stable system to show n different pictures. Images on the DNA tablet are created by hybridization with the state-dependent products of the bistable network and can be observed by AFM. The DNA tablet can also be modified to cycle through several pictures autonomously, by adapting it to a DNA oscillator.