Biomod/2012/Titech/Nano-Jugglers

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(What's Biomolecular Rocket?)
(What's Biomolecular Rocket?)
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Revision as of 13:36, 27 October 2012


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What's Biomolecular Rocket?

      
    We propose an extremely high-speed, controllable and rail-free molecular vehicle, "Biomolecular Rocket." The Biomolecular Rocket moves faster than a natural high-speed molecular motor, kinesin, by taking advantage of catalytic O2 production that progresses anywhere in a dilute H2O2 solution. For increasing the emission of O2 bubbles from the Biomolecular Rocket, we conjugated numerous catalytic engines to a micrometer-sized rocket body with the use of DNA. In addition, direction of the rail-free movement of the Biomolecular Rocket can be controlled, since we designed a photoresponsive DNA for allowing detachment of the engines from the body upon the UV light irradiation in a region-specific manner.
    The present study embodies the concept to utilize and control non-biological reactions by designing biomolecules for achieving novel functions implemented by synthetic molecular systems. We believe that our Biomolecular Rocket is a step toward advanced molecular robots that can move on long and rugged fields such as the inside of human body.
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