Biomod/2011/TUM/TNT/Results

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<h1>Survey of results</h1>
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We successfully designed a structure that folds properly with high yields [http://openwetware.org/wiki/Biomod/2011/TUM/TNT/Results#Folding_.26_Purification (link)]. It could be fluorescence labeled for FRET measurements, too. Comprehensive TEM analysis yielded insights into global structural deformations and allowed for statistical evaluation of angle and length distributions dependent on DNA binder concentrations [http://openwetware.org/wiki/Biomod/2011/TUM/TNT/Results#TEM_Image_Analysis (link)]. A huge variety of different approaches to fluorescence measurements was tested, and in single molecule measurements FRET events could be observed [http://openwetware.org/wiki/Biomod/2011/TUM/TNT/Results#Fluorescence_Measurements (link)]. Based on these experimental data and also our structure simulations and calculations, we gained new insights into the structural properties of DNA origamis [http://openwetware.org/wiki/Biomod/2011/TUM/TNT/Results#Discussion (link)].

Revision as of 20:02, 2 November 2011

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