Biomod/2011/TUM/TNT/Glossary

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Glossary

http://openwetware.org/index.php?title=Biomod/2011/TUM/TNT/Glossary&action=edit

Alle benutzen Abkürzungen (in Texten auf Wiki und im Labbook). Strukturformeln für Stoffe und Infos dazu ggf. auch nur link zu entsprechneder Seite. Benutzte programe und wofür sie verwendet werden (cadnano,cando, videosachen...)

A

B

C

D

DAPI (4�,6-diamidino-2-phenylindole): DAPI is an unfused aromatic ring system linked by bonds with torsional freedom which allow the molecules to adopt appropriate conformation to fit the helical curvature of the groove without significant perturbation of the DNA. DAPI (5) has demonstrated DNA binding via intercalation with poly[d(GC)].



DNA association binding constants

CompoundBinding modeKD (nM)
DAPIgroove binding0.9 nM
DAPIintercalation1.2×105
Sperminegroove binding4.8 uM
Ethidium bromideintercalation12.0 uM

E

Ethidium bromide

F

G

H

I

J

K

L

M

N

O

P

Q

R

S

Spermine

T

U

V

W


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