Biomod/2011/LMU/FolD'N'Assemble/Project: Difference between revisions

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===The Project===
===The Project===
Our idea is to design a nano container, that delivers medicine directly into a cell.


When molecules are transported into a cell (endocytosis), they are absorbed by endosomes. The endosomes lower their pH value to 4-5. We want to use that change of pH to open our container.
For our project we decided on designing a DNA based drug delivery vehicle.
 
DNA, as a building material, is very easy and safe to work with. So the idea to use it as a delivery vehicle came up naturally. When molecules are transported into a cell (endocytosis), they are absorbed by endosomes. The endosomes lower their pH value to 4-5. We want to use that process of pH change to open our container and release its payload.

Revision as of 03:57, 24 May 2011

The Project

For our project we decided on designing a DNA based drug delivery vehicle.

DNA, as a building material, is very easy and safe to work with. So the idea to use it as a delivery vehicle came up naturally. When molecules are transported into a cell (endocytosis), they are absorbed by endosomes. The endosomes lower their pH value to 4-5. We want to use that process of pH change to open our container and release its payload.