Biomod/2011/Harvard/HarvarDNAnos:Mission: Difference between revisions

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=Motivation=
=Motivation=
[[Image:Yellow-submarine-icon copy.jpg |thumb|right|Figure 1. "Nano-submarine"]]
[[Image:Dynamite.jpg |thumb|right|Figure 2. Simultaneous detection and amplification]]
At the beginning of summer, there were two ideas that particularly excited us (and continue to excite us today):  
At the beginning of summer, there were two ideas that particularly excited us (and continue to excite us today):  
# the development of "nano-submarines" (Figure 1) that could programmably deliver and release drugs to, for example, specific parts of the body or specific parts of the cell, and  
# the development of "nano-submarines" (Figure 1) that could programmably deliver and release drugs to, for example, specific parts of the body or specific parts of the cell, and  
# the realization of a one-step detection and amplification system (Figure 2) that could be deployed to augment the efficiency of catalytic DNA circuits or simplify the assay of molecular or heavy metal signals.  
# the realization of a one-step detection and amplification system (Figure 2) that could be deployed to augment the efficiency of catalytic DNA circuits or simplify the assay of molecular or heavy metal signals.  
 
Here is a record for our early [[Biomod/2011/Harvard/HarvarDNAnos:Brainstorming|brainstorming]].
 
[[Image:Yellow-submarine-icon copy.jpg |thumb|right|Figure 1. "Nano-submarine"]]
[[Image:Dynamite.jpg |thumb|right|Figure 2. Simultaneous detection and amplification]]
 
Here is our [[Biomod/2011/Harvard/HarvarDNAnos:Brainstorming|brainstorming]].


=Inspiration=
=Inspiration=

Revision as of 17:08, 16 October 2011

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Home              Mission              Process              Designs              Results              Resources              Team

Motivation

Figure 1. "Nano-submarine"
Figure 2. Simultaneous detection and amplification

At the beginning of summer, there were two ideas that particularly excited us (and continue to excite us today):

  1. the development of "nano-submarines" (Figure 1) that could programmably deliver and release drugs to, for example, specific parts of the body or specific parts of the cell, and
  2. the realization of a one-step detection and amplification system (Figure 2) that could be deployed to augment the efficiency of catalytic DNA circuits or simplify the assay of molecular or heavy metal signals.

Here is a record for our early brainstorming.

Inspiration

Goals

Therefore, our goal is to create DNA origami containers that can load, hold, and release cargo. To do this, we aim to:

  1. Load various forms of cargo by attaching it to the inside of a container and then closing the container
  2. Solubilize this cargo without leakage to the exterior of the container
  3. Open our container, releasing our cargo



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