Ben Cosgrove

Lauffenburger Lab

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Ben Cosgrove (BE Doctoral), in collaboration with Prof. Linda Griffith (BE/ME, MIT) Quantitative analysis of cell signaling activities and phenotypic cellular outcomes (proliferation, apoptosis, survival) in primary hepatocytes in response to multiple growth factors and cytokines administered in 2D and 3D culture systems. Multivariate signaling activity and proliferation/apoptosis outcome data are analyzed using data-driven methods to explore intracellular and extracellular cross-talk and feedback mechanisms regulating hepatocyte decision-making processes.