BME103:T930 Group 4 l2: Difference between revisions
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'''Background on Disease Markers''' | '''Background on Disease Markers''' | ||
Much like the cancer-linked genes we observed in our first lab write up, we were able to pinpoint several other diseases that can be linked to genetic variation. The first of these to be discussed will be Alzheimer's disease. Alzheimer's is a degenerative brain disease that results primary in memory loss, as well as loss of other cognitive brain functions. The Reference SNP number for this genetic variation is 63750082, and similar to the mutation that causes cancer because it is a missense mutation. However, rather than a single-nucleotide missense mutation, there are a few different mutations that can occur. Basically, in the sequence GGT, the second G can become an A, C, or T (GAT, GCT, GTT). For more information about the gene alteration, visit [http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=63750082 here!] | |||
<!--- A description of the diseases and their associated SNP's (include the database reference number and web link) ---> | <!--- A description of the diseases and their associated SNP's (include the database reference number and web link) ---> |
Revision as of 20:21, 28 November 2012
BME 103 Fall 2012 | Home People Lab Write-Up 1 Lab Write-Up 2 Lab Write-Up 3 Course Logistics For Instructors Photos Wiki Editing Help | |||||||||||||||||||||||||||||||||||
OUR TEAMLAB 2 WRITE-UPThermal Cycler EngineeringOur re-design is based upon the Open PCR system originally designed by Josh Perfetto and Tito Jankowski.
Key Features
Instructions
ProtocolsMaterials
Research and DevelopmentBackground on Disease Markers Much like the cancer-linked genes we observed in our first lab write up, we were able to pinpoint several other diseases that can be linked to genetic variation. The first of these to be discussed will be Alzheimer's disease. Alzheimer's is a degenerative brain disease that results primary in memory loss, as well as loss of other cognitive brain functions. The Reference SNP number for this genetic variation is 63750082, and similar to the mutation that causes cancer because it is a missense mutation. However, rather than a single-nucleotide missense mutation, there are a few different mutations that can occur. Basically, in the sequence GGT, the second G can become an A, C, or T (GAT, GCT, GTT). For more information about the gene alteration, visit here!
Primer Design
Illustration
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