BME100 s2015:Group14 12pmL2

In this investigation, LPS was introduced in two separate experiments, one composed of rat subjects, and the other of human subjects. The levels of Inflammotin protein were then measured and recorded for both experiments. For the rat experiment, the average inflammation was 10.516 pg/ml for 0mg of LPS and 11.112 pg/ml for 10mg. The standard deviation of the results was 2.2255516 pg/ml for 0mg, and 7.40289 pg/ml for 10mg, and the standard error was 0.9952969 for 0mg and 7.4029 for 10mg. The calculated p values for the rat subjects was 0.867403497, which is greater than the desired .05 p value. From this data, we can conclude that from the rat experiment, there is no statistical evidence that the dosage of LPS increases Inflammotin protein. The human subjects in the other experiment had an average inflammation level of 3.834 pg/ml for 0mg of LPS, 8.932 pg/ml for 5mg, 61.622 pg/ml for 10mg, and 657.941 pg/ml for 15mg. The standard deviation of these findings was 1.52301 pg/ml for 0mg, 1.593932 pg/ml for 5mg, 30.11069 pg/ml for 10mg, and 212.943 pg/ml for 15mg, and the standard error for the human section of the experiment was 0.481618 for 0mg, 0.504045 for 5mg, 9.521837 for 10mg, and 67.33848 for 15mg. The calculated p value of the human experiment was 8.59631*10^-7 for 5 mg v. 0 mg, 9.94377*10^-6 for 10 mg v. 0 mg, 1.39436*10^-8 for 15 mg v. 0 mg, 3.01859*10^-5 for 10 mg v. 5 mg, 1.57101*10^-8 for 5 mg v. 15 mg, and 6.4824*10^-8 for 10 mg v. 15 mg. A major statistical difference in each group tested was found. The corrected p value for this data is .008333. From these experiments, it cannot be concluded that Inflammotin production in rats is significantly affected by LPS dosage. It can be concluded, however, that humans are very significantly affected by LPS and do produce more Inflammotin protein because of it. Although there is no direct correlation between the two experiments, the results of each as individual entities show the extent to which LPS can increase Inflammotin protein.