BME100 f2015:Group6 1030amL3: Difference between revisions

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==Device Design==
==Device Design==
This device is a microneedle analysis implant that is virtually painless and monitors different levels of substances in the blood. Inserted into a the forearm, blood runs through the monitoring system and data is collected. A computing system determines when the vital levels are low and certain chemicals are released to begin to return vitals to normal ranges.  
This device is a microneedle analysis implant that is virtually painless and monitors different levels of substances in the blood. Inserted into a the forearm, blood runs through the monitoring system and data is collected. A computing system determines when the vital levels are low and certain chemicals are released to begin to return vitals to normal ranges.  
[[Image:EdgeDiagram.PNG|450px|Description of image]]




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| Temperature(degrees Fahrenheit) || Gold Standard || Edge
| Temperature(degrees Fahrenheit) || Gold Standard || Edge
|-
|-
| Mean || 97.24 ||97.21
| Mean || 97.2354 ||97.2100
|-
|-
| Standard Deviation || 0.19 || 0.19
| Standard Deviation || 0.1896 || 0.1852
|-
|-
| Standard Error || 0.05 || 0.05
| Standard Error || 0.0526 || 0.0514
|-
|-
| p-value || 0.0041
| p-value || 0.0041
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<br><br>
<br><br>
In this experiment, a group of 25 people use the gold standard blood test every 5 minutes for 25 minutes inside, every 10 minutes for one hour twenty minutes outside doing activity, and finally every 5 minutes for 25 minutes inside during a cool down. A small blood sample was taken and then analyzed to determine the amount of Sodium present in the blood. Then, the subjects would repeat the process using the Edge, recording their Sodium levels at the same intervals.


{| {{table}}
{| {{table}}
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<br><br>
<br><br>


In this experiment, a group of 25 people use the gold standard blood test every 5 minutes for 25 minutes inside, every 10 minutes for one hour twenty minutes outside doing activity, and finally every 5 minutes for 25 minutes inside during a cool down. A small blood sample was taken and then analyzed to determine the amount of Cortisol present in the body. Then, the subjects would repeat the process using the Edge, recording their Cortisol levels at the same intervals.
{| {{table}}
{| {{table}}
|-
|-
| Dehydration Levels (% of body weight lost) || Gold Standard || Edge
| Dehydration Levels (Amount of Sodium in blood mmol/L) || Gold Standard || Edge
|-
|-
| Mean || 0.8021||0.8242
| Mean || 140.1667||139.7917
|-
|-
| Standard Deviation || 0.5926 || 0.5779
| Standard Deviation || 2.9337 || 2.8551
|-
|-
| Standard Error || 0.1668 || 0.2315
| Standard Error || 0.8469 || 0.8242
|-
|-
| p-value || 0.0230
| p-value || 0.0017
|-
|-
| Pearson's R || 0.9989
| Pearson's R || 0.9944


|}
|}


<br><br>
<br><br>
In this experiment, a group of 25 people use the gold standard pulse ox every 2 minutes for ten minutes inside, every five minutes for forty minutes outside doing activity, and finally every 2 minutes for 10 minutes inside during a cool down. Then, the subjects would repeat the process using the Edge, recording their blood oxygen level at the same intervals.


{| {{table}}
{| {{table}}
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Cortisol Levels  
Cortisol Levels  


[[Image:CortisolBar.png‎|200px|Description of image]]
[[Image:Cortisollevels.png|200px|Description of image]]
The gold stars show significance between the Edge and the gold standard.
[[Image:CortisolScatter.png‎|200px|Description of image]]
[[Image:CortisolScatter.png‎|200px|Description of image]]


Dehydration  
Dehydration  


[[Image:DehydrationBar.png‎|200px|Description of image]]
[[Image:Sodiumlevels.png|200px|Description of image]]
[[Image:DehydrationScatter.png‎|200px|Description of image]]
The gold stars show significance between the Edge and the gold standard.
[[Image:Dehydrationscatter.png|200px|Description of image]]
 


Body Temperature
Body Temperature


[[Image:TemperatureBar.png‎|200px|Description of image]]
[[Image:Bodytemperature.png|200px|Description of image]]
The gold stars show significance between the Edge and the gold standard.
[[Image:TemperatureScatter.png‎|200px|Description of image]]
[[Image:TemperatureScatter.png‎|200px|Description of image]]


Oxygen
Oxygen
   
   
[[Image:OxygenBar.png‎|200px|Description of image]]
 
[[Image:Oxygenlevels.png|200px|Description of image]]
The gold stars show significance between the Edge and the gold standard.
[[Image:OxygenScatter.png‎|200px|Description of image]]
[[Image:OxygenScatter.png‎|200px|Description of image]]
<br><br>
<br><br>

Latest revision as of 18:30, 4 October 2015

BME 100 Fall 2015 Home
People
Lab Write-Up 1 | Lab Write-Up 2 | Lab Write-Up 3
Lab Write-Up 4 | Lab Write-Up 5 | Lab Write-Up 6
Course Logistics For Instructors
Photos
Wiki Editing Help


OUR TEAM

Name: Andres X. Gandara
Name: Caroline Dolt
Name: Connor Beck
Name: Chricitan Adane
Name: Rex Moore
Name: Kamrie Ickes

LAB 3A WRITE-UP

Descriptive Statistics

Temperature(degrees Fahrenheit) Gold Standard Spree Band
Mean 97.26 99.23
Standard Deviation 1.17 1.34
Standard Error 0.06 0.07
Heart Rate(beats per minute) Gold Standard Spree Band
Mean 88.92493 88.3079
Standard Deviation 23.2322 22.99431
Standard Error 1.212711 1.200293




Results

Temperature

Description of image

Description of image

Heart Rate

Description of image

Description of image



Analysis

For the heart rate study a paired T-test was done to determine significance. A paired t-test was done because the subjects that used the Spree headband were the same subjects who used the gold standard. For the heart rate test, the p-value was 0.3902. This value shows that there was not significance between the gold standard and the spree head band because p>.05. This suggests that the Spree headband is not an accurate device to measure heart rate. A scatter plot for the data was also made and Pearsons' R coefficient was 0.8233. This means that the Spree headband has a moderately positive relationship with the gold standard but not a significant relationship. In combination with the t-test, it can be said with certainty that there is not a strong relationship between the data collected from the Spree headband and the data from the gold standard device.
For the temperature study a paired t-test was also performed to determine significance. Similar to the heart rate study, the subjects that wore the Spree headband also used the thermometer as the gold standard. For the temperature test, the p-value was 4.08 x 10^-69. This is much smaller than a value of .05 which suggests that there is significance to the data, meaning the Spree headband is an accurate device to measure temperature. A scatter plot for the data was made and Pearson's R coefficient was 0.046. This number shows that there is almost no correlation between the Spree headband and the gold standard even though there is significance between the two.

Summary/Discussion

There are many design flaws with the Spree fitness headband. First, it's difficult to connect with to Bluetooth and this took several minutes. The bluetooth device in the headband should be stronger and able to deal with high traffic in case multiple people were wearing them in the gym. Another flaw was that only levels of temperature are shown instead of the degree values. This would be a simple fix within the app to show the degree value since the device needs to take the person's temperature to put it in a temperature level. A third technical flaw was the erratic heart rate readings that were inconsistent with the changes in temperature. This is a sensitivity error on the device's half which could be fixed by a more consistent and reliable heart rate monitor. Aside from the technology, the band is very expensive in comparison to the quality. There's many fitness devices in the market that are more popular because they're lower in price and higher in quality. The company should lower the price to something more reasonable around seventy-five to one hundred dollars. After wearing it for an hour, the band gave the wearer a headache and left strange imprints on their forehead. A fix for this would be to place the band somewhere other than the head, such as around the arm, which would make it more aesthetically pleasing as well.




LAB 3B WRITE-UP

Target Population and Need

Our target population consists of people in high stress, physically demanding jobs such as firefighters or military officers. The problem is that the demanding nature of these jobs can cause negative effects on the body. Often in tense situations, subjects could become dehydrated or overheated, leading to unconsciousness or death. The goal is to know when the subject is approaching a dangerous level of dehydration, temperature, or oxygen level and take action to prevent harm. Thousands of people across the globe could benefit from this device, from a hiker in the Rocky Mountains to a CIA agent in Syria. However, the expense and medical implantation of the device would limit the number of people who can use it.


Description of image



Device Design

This device is a microneedle analysis implant that is virtually painless and monitors different levels of substances in the blood. Inserted into a the forearm, blood runs through the monitoring system and data is collected. A computing system determines when the vital levels are low and certain chemicals are released to begin to return vitals to normal ranges.

Description of image




Inferential Statistics

In this experiment, a group of 25 people use the gold standard thermometer every 2 minutes for ten minutes inside, every five minutes for forty minutes outside doing activity, and finally every 2 minutes for 10 minutes inside during a cool down. Then, the subjects would repeat the process using the Edge, recording their temperature at the same intervals.

Temperature(degrees Fahrenheit) Gold Standard Edge
Mean 97.2354 97.2100
Standard Deviation 0.1896 0.1852
Standard Error 0.0526 0.0514
p-value 0.0041
Pearson's R 0.9809



In this experiment, a group of 25 people use the gold standard blood test every 5 minutes for 25 minutes inside, every 10 minutes for one hour twenty minutes outside doing activity, and finally every 5 minutes for 25 minutes inside during a cool down. A small blood sample was taken and then analyzed to determine the amount of Sodium present in the blood. Then, the subjects would repeat the process using the Edge, recording their Sodium levels at the same intervals.

Cortisol Levels (nmol/L) Gold Standard Edge
Mean 435.2353 438.3529
Standard Deviation 169.9617 168.8293
Standard Error 41.2218 40.9471
p-value 0.0441
Pearson's R 0.9994



In this experiment, a group of 25 people use the gold standard blood test every 5 minutes for 25 minutes inside, every 10 minutes for one hour twenty minutes outside doing activity, and finally every 5 minutes for 25 minutes inside during a cool down. A small blood sample was taken and then analyzed to determine the amount of Cortisol present in the body. Then, the subjects would repeat the process using the Edge, recording their Cortisol levels at the same intervals.

Dehydration Levels (Amount of Sodium in blood mmol/L) Gold Standard Edge
Mean 140.1667 139.7917
Standard Deviation 2.9337 2.8551
Standard Error 0.8469 0.8242
p-value 0.0017
Pearson's R 0.9944



In this experiment, a group of 25 people use the gold standard pulse ox every 2 minutes for ten minutes inside, every five minutes for forty minutes outside doing activity, and finally every 2 minutes for 10 minutes inside during a cool down. Then, the subjects would repeat the process using the Edge, recording their blood oxygen level at the same intervals.

Oxygen Level in the Blood (Percent of Oxygen in Blood) Gold Standard Edge
Mean 94.7714 94.9429
Standard Deviation 2.5723 2.6647
Standard Error 0.6875 2.6647
p-value 0.0305
Pearson's R 0.9955



Graph

Cortisol Levels

Description of image The gold stars show significance between the Edge and the gold standard. Description of image


Dehydration

Description of image The gold stars show significance between the Edge and the gold standard. Description of image


Body Temperature

Description of image The gold stars show significance between the Edge and the gold standard. Description of image

Oxygen


Description of image The gold stars show significance between the Edge and the gold standard. Description of image