BMCB625:Exon Jxn Complex

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BMCB625 Advanced Topics in Molecular Biology

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Papers

  1. Bono F, Ebert J, Lorentzen E, and Conti E. The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA. Cell. 2006 Aug 25;126(4):713-25. DOI:10.1016/j.cell.2006.08.006 | PubMed ID:16923391 | HubMed [Bono]

Bonus Materials

<biblio>

  1. Andersen pmid=16931718
  1. Le Hir H, Nott A, Moore MJ. How introns influence and enhance eukaryotic gene expression.

Trends Biochem Sci. 2003 Apr;28(4):215-20. Review. PMID: 12713906 [PubMed - indexed for MEDLINE] [[1]]


  • A good overview on how introns may influence gene expression, and why the EJC (Exon Junction Complex) is such an important player in the "mRNA to translation steps" in the control of gene expression.

(Homework) Questions

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