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'''''Plant-Environment Interactions and <br>Molecular Pharming'''''<br><br>
'''''Genetics of Plant-Environment Interactions'''''<br><br>
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Our lab studies the genetic and molecular bases for the adaptation of plants to their local environments. We mainly focus on the adaptation to stress (abiotic and biotic) and how this can be translated in an efficient molecular pharming (production of pharmaceutical compounds in plants) under the current challenges of climate change.
Dear visitor,<br><br>
Welcome to the webpage of the '''Alcázar Lab''' at the University of Barcelona.
We study the genetic and molecular bases for the '''adaptation of plants to their local environments'''. We focus on the evolutionary adaptation of plant populations to '''abiotic and biotic stresses''', which are major challenges for plant survival. Derived from our basic research, we investigate ways for improving stress protection.<br><br>
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For a more detailed view of our research, please have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. You can follow an updated list of our activities and publications in the NEWS section below.<br>


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Current projects <br><br>
'''CURRENT AREAS OF RESEARCH'''
'''Disease resistance in plants ''' <br>
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We're currently studying the evolution of ''NB-LRR'' immune-receptor genes and other interacting loci that condition defense against evolving pathogens and how this derives in immune-related hybrid incompatibility, an important obstacle in plant breeding. We address these questions using molecular biology, population genetics and biochemical approaches. This research is complemented by the study of the modulation of ''NB-LRR'' signaling by temperature which is important under the current climate change predictions.  <br><br>
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'''Natural variation of stress-induced metabolites''' <br>
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We study the genetic bases for the naturally occurring  variation of some stress metabolites involved in resistance traits to abiotic and biotic stresses in collaboration with different laboratories. We identify natural compounds which protect plants from stress. Through molecular approaches we improve the resistance of plants to different stresses. <br>
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'''Molecular pharming''' <br>
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We produce proteins of pharmaceutical interest in plants and study ways to improve their productivity under different environments to adapt to the requirements of local climates.
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'''1. Natural variation and evolution of immune resistance genes in plants.''' <br>
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Plant resistance to pathogens is an important field of research with direct applications and we study it from an evolutionary, population genetics and molecular view. We currently study the '''molecular bases and evolution of ''Resistance'' genes''' and other loci that condition immune activation. We do so by studying Arabidopsis natural hybrids that exhibit activation of defense and fitness loss. We explore the mechanisms that have naturally evolved in plant populations to resist against pathogens and how the immune receptor repertoire is selected and diversified. At the direct interface between plants and the environment, we study how temperature modulates some plant immune responses.<br>
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'''2. Natural variation of abiotic stress tolerance and adaptation'''
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For a more detailed view of our research, have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. <br> For general public information have a look at [http://alcazar.openwetware.org/Alcazar_Youtube.html +info]. <br><br>
We investigate the molecular and genetic mechanisms underlying the naturally occurring '''tolerance to abiotic stresses in plant populations'''. We're currently studying the genetic bases for the naturally occurring variation of '''stress protective metabolites''' that condition resistance in plants in collaboration with A.F.Tiburcio Lab.<br>
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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
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'''JOB OFFERS''' <br>
'''NEW'''
A 3-years PhD position (2015-2017) is available in our laboratory to study
Arabidopsis ''NB-LRR'' evolution and interactions with ''Hyaloperonospora arabidopsidis'' pathogens.
Interested candidates should send us their CV and two letters of reference by e-mail.
Questions should be addressed to the same e-mail address below.
Application period: 1 July - 15 September 2014
Expected starting date: January 2015
[mailto:ralcazar@ub.edu Contact]


8.01.2015. Kosta joins our Lab as PhD student with an FI grant associated with HI project. Congrats!


In PLoS Genetics: [http://openwetware.org/wiki/Alcazar:pressDec2014 '''Exploring the maintenance and diversity of plant immunity genes in nature''']
by Alcázar et al.


'''LATEST PUBLICATIONS''' <br>
[http://www.frontiersin.org/books/Plant_polyamines_in_stress_and_development/340 E-book in Frontiers in Plant Science 2014, by Antonio F. Tiburcio and Rubén Alcázar, Eds.]
   
   
  Editorial article of upcoming e-book in Frontiers in Plant Science. Editors: Ruben Alcazar & A.F. Tiburcio.
  Editorial article by Ruben Alcazar & A.F. Tiburcio in Frontiers in Plant Science 2014:
  [http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00319/full Plant polyamines in stress and development: an emerging area of research in plant sciences] <br>
  [http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00319/full Plant polyamines in stress and development: an emerging area of research in plant sciences] <br>
 
  [http://link.springer.com/article/10.1007/s00425-014-2055-9 '''The Roles of Polyamines during the lifespan of plants:from development to stress''']
  [http://link.springer.com/article/10.1007/s00425-014-2055-9 '''Review: The Roles of Polyamines during the lifespan of plants:from development to stress''']
  Tiburcio AF, Altabella T, Bitrián M and Alcázar R. (2014) Planta 240: 1-18.<br>
  Tiburcio AF, Altabella T, Bitrián M and Alcázar R. (2014) Planta 240: 1-18.<br>
'''More news'''
<br>
Ruben Alcazar Lab granted by the Spanish Programme of Scientific and Technical Excellence 2014.


''' PRESS RELEASES'''<br>
[http://www.ub.edu/web/ub/en/menu_eines/noticies/2015/01/020.html? Alcázar Lab work highlighted by the University of Barcelona 20.01.15]<br>
[http://www.ub.edu/noticies/cgi/event.pl?id=62490&noticiaub=FARMACIA Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015]<br>
[http://sefv.net/files/sd_publicaciones/58.pdf Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015]<br>
[http://www.mpipz.mpg.de/4042700/PM_Parker_2015 PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.]<br>
[http://www.ub.edu/web/ub/en/menu_eines/noticies/2013/11/063.html? Arabidopsis semidwarfs: the green revolution in nature] 02.12.2013. University of Barcelona.<br>
[http://www.mpipz.mpg.de/5389/news_publication_619091 Hybrid plants with over-reactive immune system] 17.11.2010. Max Planck Society.
   
   
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[http://www.ub.edu/farmacia/ The Faculty] | [http://www.ub.edu The University] | [http://bkc.upc.ub.edu/ The Campus] | [http://www.ccit.ub.edu/EN/home.html Scientific and Technological Centers]
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Rubén Alcázar is Ramón y Cajal Researcher at the Department of Natural Products, Plant Biology and Soil Science of the [http://www.ub.edu University of Barcelona].<br>
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<br>'''Research in Alcázar Lab is supported by:'''
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Full address: Facultat de Farmacia, Universitat de Barcelona, Unitat de Fisiologia Vegetal. Avda Joan XXIII 27-31, 08028 Barcelona (Spain). <br>
[[Image:Alcazar_funding.png|900px]]
Tel +34 934 024 492 Fax +34 934 029 043 <br><br>
 
<p>This wiki site is built under [http://www.openwetware.org Openwetware], an open access movement promoting the sharing of information among researchers.</p>
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* 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.  
* Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
* BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).

Revision as of 12:14, 22 January 2015




Dept. Biology, Healthcare & Environment
Section of Plant Physiology
Facultat de Farmàcia, Av. Joan XXIII 27-31
08028 Barcelona, Spain

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Genetics of Plant-Environment Interactions

Dear visitor,

Welcome to the webpage of the Alcázar Lab at the University of Barcelona. We study the genetic and molecular bases for the adaptation of plants to their local environments. We focus on the evolutionary adaptation of plant populations to abiotic and biotic stresses, which are major challenges for plant survival. Derived from our basic research, we investigate ways for improving stress protection.


For a more detailed view of our research, please have a look at our Research Projects and Scientific Publications sections. You can follow an updated list of our activities and publications in the NEWS section below.




CURRENT AREAS OF RESEARCH


1. Natural variation and evolution of immune resistance genes in plants.

Plant resistance to pathogens is an important field of research with direct applications and we study it from an evolutionary, population genetics and molecular view. We currently study the molecular bases and evolution of Resistance genes and other loci that condition immune activation. We do so by studying Arabidopsis natural hybrids that exhibit activation of defense and fitness loss. We explore the mechanisms that have naturally evolved in plant populations to resist against pathogens and how the immune receptor repertoire is selected and diversified. At the direct interface between plants and the environment, we study how temperature modulates some plant immune responses.

2. Natural variation of abiotic stress tolerance and adaptation

We investigate the molecular and genetic mechanisms underlying the naturally occurring tolerance to abiotic stresses in plant populations. We're currently studying the genetic bases for the naturally occurring variation of stress protective metabolites that condition resistance in plants in collaboration with A.F.Tiburcio Lab.

News and Announcements e-Board

8.01.2015. Kosta joins our Lab as PhD student with an FI grant associated with HI project. Congrats!

In PLoS Genetics: Exploring the maintenance and diversity of plant immunity genes in nature
by Alcázar et al.

E-book in Frontiers in Plant Science 2014, by Antonio F. Tiburcio and Rubén Alcázar, Eds.

Editorial article by Ruben Alcazar & A.F. Tiburcio in Frontiers in Plant Science 2014:
Plant polyamines in stress and development: an emerging area of research in plant sciences 


Review: The Roles of Polyamines during the lifespan of plants:from development to stress
Tiburcio AF, Altabella T, Bitrián M and Alcázar R. (2014) Planta 240: 1-18.

PRESS RELEASES

Alcázar Lab work highlighted by the University of Barcelona 20.01.15

Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015

Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015

PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.

Arabidopsis semidwarfs: the green revolution in nature 02.12.2013. University of Barcelona.

Hybrid plants with over-reactive immune system 17.11.2010. Max Planck Society.


Rubén Alcázar is Ramón y Cajal Researcher at the Department of Natural Products, Plant Biology and Soil Science of the University of Barcelona.


Research in Alcázar Lab is supported by:


  • 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
  • Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
  • BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).
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