Alcazar

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'''''Plant-Environment Interactions and <br>Molecular Pharming'''''<br><br>
 
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Our lab studies the genetic and molecular bases for the adaptation of plants to their local environments. We mainly focus on the adaptation to stress (abiotic and biotic) and how this can be translated in an efficient molecular pharming (production of pharmaceutical compounds in plants) under the current challenges of climate change.
 
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'''''Laboratory of Plant-Environment Interactions'''''<br>
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'''''Dear visitor, Benvolgut visitant, Estimado visitante, Sehr geehrte besucher,'''''<br>
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<br> Welcome to the webpage of the '''Laboratory of Plant-Environment Interactions (R. Alcazar)''' at the Deparment of Biology, Health & Environment of the University of Barcelona. <br><br>
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We investigate the '''adaptation of plants to local environments'''. We focus on the evolutionary adaptation of plant populations to '''abiotic and biotic stresses''', which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.<br>
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For a more detailed view of our research, please have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.<br>
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Current projects <br><br>
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'''Disease resistance in plants ''' <br>
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'''AREAS OF RESEARCH'''
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We're currently studying the evolution of ''NB-LRR'' immune-receptor genes and other interacting loci that condition defense against evolving pathogens and how this derives in immune-related hybrid incompatibility, an important obstacle in plant breeding. We address these questions using molecular biology, population genetics and biochemical approaches. This research is complemented by the study of the modulation of ''NB-LRR'' signaling by temperature which is important under the current climate change predictions.  <br><br>
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'''Natural variation of stress-induced metabolites''' <br>
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We study the genetic bases for the naturally occurring  variation of some stress metabolites involved in resistance traits to abiotic and biotic stresses in collaboration with different laboratories. We identify natural compounds which protect plants from stress. Through molecular approaches we improve the resistance of plants to different stresses. <br>
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'''Molecular pharming''' <br>
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We produce proteins of pharmaceutical interest in plants and study ways to improve their productivity under different environments to adapt to the requirements of local climates.
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'''1. Disease resistance in plants''' <br>
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We study the evolution of disease ''Resistance'' genes and other loci that condition plant immune activation in the model species ''Arabidopsis thaliana''. We make use of natural populations of plants and pathogens to address molecular and evolutionary aspects of pathogen recognition in the wild.  At the direct interface between plants and the environment, we study how temperature modulates some NB-LRR triggered plant immune responses.<br>
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'''2. Natural variation of abiotic stress tolerance and adaptation'''<br>
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Polyamines are small amines which accumulate in response to abiotic and biotic stress. We investigate the implications of polyamines in plant stress protection through the analysis of their mechanisms of action. <br>
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For a more detailed view of our research, have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. <br> For general public information have a look at [http://alcazar.openwetware.org/Alcazar_Youtube.html +info]. <br><br>
 
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'''Collaborators'''<br>
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Joachim Kopka, [http://www.mpimp-golm.mpg.de MPIMP, Germany]<br>
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Jane Parker, [http://www.mpipz.mpg.de MPIPZ, Germany]<br>
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[http://www.ccit.ub.edu/EN/home.html CCiT, University of Barcelona]<br>
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National Centre of Genomic Analysis [http://www.cnag.cat CNAG]<br>
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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
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'''JOB OFFERS''' <br>
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Publications 2016
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  '''NEW'''
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  22/04/2016 [http://www.ncbi.nlm.nih.gov/pubmed/27082651 Parker lab: Ler RPP1-like R8 is required for autoimmunity triggered by EDS1 nuclear accumulation]
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A 3-years PhD position (2015-2017) is available in our laboratory to study
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Arabidopsis ''NB-LRR'' evolution and interactions with ''Hyaloperonospora arabidopsidis'' pathogens.
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  Interested candidates should send us their CV and two letters of reference by e-mail.
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  15/03/2016 In Frontiers Plant Sci: [http://journal.frontiersin.org/article/10.3389/fpls.2016.00401/abstract GWAS analysis for Arabidopsis guazatine tolerance]
   
   
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  Questions should be addressed to the same e-mail address below.
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  22/01/2016 In Plant Cell & Environment:  [http://www.ncbi.nlm.nih.gov/pubmed/26791972 tSpm triggers salinity tolerance in Arabidopsis]
   
   
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  Application period: 1 July - 15 September 2014
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  01/02/2016 In Frontiers Plant Sci: [http://journal.frontiersin.org/article/10.3389/fpls.2016.00173/abstract Metabolic profiling of atpao4 mutants under dark induced senescence]
   
   
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  Expected starting date: January 2015
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  In press: Drought Stress Tolerance in Relation to Polyamine Metabolism in Plants, book chapter in Springer.
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[mailto:ralcazar@ub.edu Contact]
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'''LATEST PUBLICATIONS''' <br>
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01/01/2016 Iñigo Aristizábal (Degree in Biochemistry and Mol. Biology) joins our lab as UB Master 2015/16.
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''' PRESS RELEASES'''<br>
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[http://www.ub.edu/web/ub/en/menu_eines/noticies/2015/01/020.html? Alcázar Lab work highlighted by the University of Barcelona 20.01.15]<br>
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[http://www.ub.edu/noticies/cgi/event.pl?id=62490&noticiaub=FARMACIA Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015]<br>
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[http://sefv.net/files/sd_publicaciones/58.pdf Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015]<br>
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[http://www.mpipz.mpg.de/4042700/PM_Parker_2015 PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.]<br>
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[http://www.ub.edu/web/ub/en/menu_eines/noticies/2013/11/063.html? Arabidopsis semidwarfs: the green revolution in nature] 02.12.2013. University of Barcelona.<br>
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[http://www.mpipz.mpg.de/5389/news_publication_619091 Hybrid plants with over-reactive immune system] 17.11.2010. Max Planck Society.
   
   
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Editorial article of upcoming e-book in Frontiers in Plant Science. Editors: Ruben Alcazar & A.F. Tiburcio.
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[http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00319/full Plant polyamines in stress and development: an emerging area of research in plant sciences] <br>
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Rubén Alcázar is Ramón y Cajal Researcher at the Department of Natural Products, Plant Biology and Soil Science of the [http://www.ub.edu University of Barcelona].<br>
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<br>'''Research in Alcázar Lab is supported by:'''
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[http://link.springer.com/article/10.1007/s00425-014-2055-9 '''The Roles of Polyamines during the lifespan of plants:from development to stress''']
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[[Image:Alcazar_funding.png|900px]]
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Tiburcio AF, Altabella T, Bitrián M and Alcázar R. (2014) Planta 240: 1-18.
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* 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
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* Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
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* BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).
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[http://www.ub.edu/farmacia/ The Faculty] | [http://www.ub.edu The University] | [http://bkc.upc.ub.edu/ The Campus] | [http://www.ccit.ub.edu/EN/home.html Scientific and Technological Centers]
 
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Full address: Facultat de Farmacia, Universitat de Barcelona, Unitat de Fisiologia Vegetal. Avda Joan XXIII 27-31, 08028 Barcelona (Spain). <br>
 
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Tel +34 934 024 492 Fax +34 934 029 043 <br><br>
 
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<p>This wiki site is built under [http://www.openwetware.org Openwetware],  an open access movement promoting the sharing of information among researchers.</p>
 

Current revision



Faculty of Pharmacy and Food Sciences
University of Barcelona (UB)
Department of Biology,
Health & Environment
Av. Joan XXIII 27-31
08028 Barcelona

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Laboratory of Plant-Environment Interactions

Dear visitor, Benvolgut visitant, Estimado visitante, Sehr geehrte besucher,

Welcome to the webpage of the Laboratory of Plant-Environment Interactions (R. Alcazar) at the Deparment of Biology, Health & Environment of the University of Barcelona.

We investigate the adaptation of plants to local environments. We focus on the evolutionary adaptation of plant populations to abiotic and biotic stresses, which are major challenges for plant survival under the current climate change predictions. Derived from our research, we investigate ways for improving stress protection.

For a more detailed view of our research, please have a look at our Research Projects and Scientific Publications sections. You can follow an updated list of our activities and publications in the NEWS section below. For any other enquires, do not hesitate to contact us directly.







AREAS OF RESEARCH



1. Disease resistance in plants
We study the evolution of disease Resistance genes and other loci that condition plant immune activation in the model species Arabidopsis thaliana. We make use of natural populations of plants and pathogens to address molecular and evolutionary aspects of pathogen recognition in the wild. At the direct interface between plants and the environment, we study how temperature modulates some NB-LRR triggered plant immune responses.

2. Natural variation of abiotic stress tolerance and adaptation
Polyamines are small amines which accumulate in response to abiotic and biotic stress. We investigate the implications of polyamines in plant stress protection through the analysis of their mechanisms of action.



Collaborators
Joachim Kopka, MPIMP, Germany
Jane Parker, MPIPZ, Germany
CCiT, University of Barcelona
National Centre of Genomic Analysis CNAG


News and Announcements e-Board

Publications 2016
22/04/2016 Parker lab: Ler RPP1-like R8 is required for autoimmunity triggered by EDS1 nuclear accumulation

15/03/2016 In Frontiers Plant Sci: GWAS analysis for Arabidopsis guazatine tolerance

22/01/2016 In Plant Cell & Environment:  tSpm triggers salinity tolerance in Arabidopsis

01/02/2016 In Frontiers Plant Sci: Metabolic profiling of atpao4 mutants under dark induced senescence

In press: Drought Stress Tolerance in Relation to Polyamine Metabolism in Plants, book chapter in Springer.


01/01/2016 Iñigo Aristizábal (Degree in Biochemistry and Mol. Biology) joins our lab as UB Master 2015/16.

PRESS RELEASES

Alcázar Lab work highlighted by the University of Barcelona 20.01.15
Rubén Alcázar research highlighted by the Faculty of Pharmacy at UB, January 2015
Alcázar Lab work highlighted by the Bulletin of the Spanish Society of Plant Physiology, SEFV. January, 2015
PLoS Genet 2014 highlight by Max Planck Institute, Cologne. 11.12.14.
Arabidopsis semidwarfs: the green revolution in nature 02.12.2013. University of Barcelona.
Hybrid plants with over-reactive immune system 17.11.2010. Max Planck Society.



Rubén Alcázar is Ramón y Cajal Researcher at the Department of Natural Products, Plant Biology and Soil Science of the University of Barcelona.



Research in Alcázar Lab is supported by:


  • 7th Framework Programme. Marie Curie Career Integration Grant (DISEASENVIRON, PCIG10-GA-2011-303568) of the European Union.
  • Ramón y Cajal Program (RYC-2011-07847) of the Ministerio de Ciencia e Innovación (Spain).
  • BFU2013-41337-P grant of the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia (Ministerio de Economía y Competitividad, Spain).

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