Alcazar

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'''''Plant-Environment Interactions'''''
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'''''Plant-Environment Interactions and <br>Molecular Pharming'''''<br><br>
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Our lab studies the genetic and molecular bases for the adaptation of plants to their local environments. We mainly focus on the adaptation to stress (abiotic and biotic) and how this can be translated in an efficient molecular pharming (production of pharmaceutical compounds in plants) under the current challenges of climate change.
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Current projects <br><br>
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'''Disease resistance in plants ''' <br>
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We're currently studying the evolution of ''NB-LRR'' immune-receptor genes and other interacting loci that condition defense against evolving pathogens and how this derives in immune-related hybrid incompatibility, an important obstacle in plant breeding. We address these questions using molecular biology, population genetics and biochemical approaches. This research is complemented by the study of the modulation of ''NB-LRR'' signaling by temperature which is important under the current climate change predictions.  <br><br>
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'''Natural variation of stress-induced metabolites''' <br>
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We study the genetic bases for the naturally occurring  variation of some stress metabolites involved in resistance traits to abiotic and biotic stresses in collaboration with different laboratories. We identify natural compounds which protect plants from stress. Through molecular approaches we improve the resistance of plants to different stresses. <br>
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'''Molecular pharming''' <br>
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We produce proteins of pharmaceutical interest in plants and study ways to improve their productivity under different environments to adapt to the requirements of local climates.
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We're interested in genetics of natural variation, population genetics and molecular biology. We want to know how climate change is shaping plant's resistance and tolerance traits under a combined multidisciplinary approach. Our lab undertakes a research approach that looks for the genetic and molecular basis of naturally occurring quantitative variation in biotic and abiotic stress responses, and how these interact with the environment (genotype-by-environment interactions). This multidisciplinary approach will allow a better understanding of the natural evolution of stress pathways in plants and efficient know-how transfer to practical applications.<br>
 
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For a more detailed view of our research plans, please have a look at our [http://openwetware.org/wiki/Alcazar:Research Research Projects] and [http://openwetware.org/wiki/Alcazar:Publications Scientific Publications] sections.
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For a more detailed view of our research, have a look at our [http://alcazar.openwetware.org/Research.html Research Projects] and [http://alcazar.openwetware.org/Publications.html Scientific Publications] sections. <br> For general public information have a look at [http://alcazar.openwetware.org/Alcazar_Youtube.html +info]. <br><br>
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'''LATEST NEWS'''
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[[Image:Announcement_alcazar.jpg |100px]] '''News and Announcements e-Board'''<br>
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  '''16, August 2013'''  
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'''JOB OFFERS''' <br>
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  '''NEW'''
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A 3-years PhD position (2015-2017) is available in our laboratory to study
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Arabidopsis ''NB-LRR'' evolution and interactions with ''Hyaloperonospora arabidopsidis'' pathogens.
   
   
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  The ''Arabidopsis thaliana'' green revolution
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  Interested candidates should send us their CV and two letters of reference by e-mail.
   
   
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Questions should be addressed to the same e-mail address below.
   
   
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  '''Barboza L, Effgen S, Alonso-Blanco C, Kooke R, Keurentjes J, Koornneef M and Alcázar R.
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  Application period: 1 July - 15 September 2014
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'''''Arabidopsis semi-dwarfs evolved from independent mutations in GA20ox1, orthologue to'''''
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'''''green revolution dwarf alleles in rice and barley.''''' '''PNAS, in press.'''
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  This article by '''Barboza et al.''' determines the evolutionary basis of the GA5 locus,
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  Expected starting date: January 2015
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encoding one of the last enzymes of the gibberellic acid biosynthesis pathway, and
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involved in semi-dwarf phenotypes that naturally segregate in ''A.thaliana'' populations.
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Interestingly, the same locus has been targeted by crop breeding for the isolation
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of the so-called green revolution alleles in rice and barley.
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  This study demonstrates that the use of ''A.thaliana'' natural variation enables
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  [mailto:ralcazar@ub.edu Contact]
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the identification of genes and alleles which can be successful for plant breeding.
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'''24, July 2013'''
 
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Rubén Alcázar editor of Advances in Botany [http://www.hindawi.com/journals/abot/editors/ Editorial Board] <br>
 
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'''February 2013'''
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'''LATEST PUBLICATIONS''' <br>
   
   
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  Rubén Alcázar guest editor of the research topic "Polyamines in stress and development"<br> in [http://www.frontiersin.org/Plant_Metabolism_and_Chemodiversity/researchtopics/Plant_polyamines_in_stress_and/1527 Frontiers in Plant Sci.]
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  Editorial article of upcoming e-book in Frontiers in Plant Science. Editors: Ruben Alcazar & A.F. Tiburcio.
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[http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00319/full Plant polyamines in stress and development: an emerging area of research in plant sciences] <br>
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'''PREVIOUS ANNOUNCEMENTS'''
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[http://link.springer.com/article/10.1007/s00425-014-2055-9 '''The Roles of Polyamines during the lifespan of plants:from development to stress''']
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Tiburcio AF, Altabella T, Bitrián M and Alcázar R. (2014) Planta 240: 1-18.
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* Our lab has started research activities as from 1st Dec 2012 and is recruting students interested in our research activities. Interested people should contact us directly.
 
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* '''25.10.2012''' R.A. granted by Marie Curie Actions for the project DISEASENVIRON.
 
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* '''25.10.2012'''  Review on new open access journal 'Metabolites' published. [http://www.mdpi.com/2218-1989/2/3/516 read]
 
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*'''''08.10.2012''''' Interessat en realitzar la tesi doctoral o màster al nostre grup? Contacta per e-mail amb nosaltres.
 
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*'''''04.10.2012''''' New lab webpage version released in OpenWetWare.
 
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'''SEMINARS - Keep updated with our research''' <br><br>
 
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Summer break until September. There are no seminars scheduled.
 
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  Previous seminars: <br>
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'''16 April 12:30h'''<br>
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Location: Aula Magna, Facultat de Farmàcia, Universitat de Barcelona <br>
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Avda Joan XXIII 27-31, 08028 Barcelona<br>
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Title: Incompatibilitats genètiques del sistema immune de les plantes.<br>
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Language: Catalan <br><br>
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'''Address:'''
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[http://www.ub.edu/farmacia/ The Faculty] | [http://www.ub.edu The University] | [http://bkc.upc.ub.edu/ The Campus] | [http://www.ccit.ub.edu/EN/home.html Scientific and Technological Centers]
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Facultat de Farmàcia - Universitat de Barcelona (UB) <br>
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Departament de Productes Naturals, Biologia Vegetal i Edafologia<br>
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Unitat de Fisiologia Vegetal - Edifici A, 2a Planta <br>
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Avda Joan XXIII 27-31, 08028 Barcelona<br>
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Spain<br>
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Esta página web así como sus contenidos se ofrecen en inglés excepto el apartado +INFO dirigido al público
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en general.<br>
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Aquesta pàgina web així com els seus contiguts estan en anglès, exceptuant l'apartat +INFO dirigit al públic
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Full address: Facultat de Farmacia, Universitat de Barcelona, Unitat de Fisiologia Vegetal. Avda Joan XXIII 27-31, 08028 Barcelona (Spain). <br>
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en general.
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Tel +34 934 024 492 Fax +34 934 029 043 <br><br>
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<p>This wiki site is built under [http://www.openwetware.org Openwetware],  an open access movement promoting the sharing of information among researchers.</p>
<p>This wiki site is built under [http://www.openwetware.org Openwetware],  an open access movement promoting the sharing of information among researchers.</p>

Current revision



University of Barcelona
Barcelona Campus of Knowledge
Barcelona, Spain
Contact
alcazar.openwetware.org--thumb.jpg


Plant-Environment Interactions and
Molecular Pharming


Our lab studies the genetic and molecular bases for the adaptation of plants to their local environments. We mainly focus on the adaptation to stress (abiotic and biotic) and how this can be translated in an efficient molecular pharming (production of pharmaceutical compounds in plants) under the current challenges of climate change.



Current projects

Disease resistance in plants

We're currently studying the evolution of NB-LRR immune-receptor genes and other interacting loci that condition defense against evolving pathogens and how this derives in immune-related hybrid incompatibility, an important obstacle in plant breeding. We address these questions using molecular biology, population genetics and biochemical approaches. This research is complemented by the study of the modulation of NB-LRR signaling by temperature which is important under the current climate change predictions.


Natural variation of stress-induced metabolites

We study the genetic bases for the naturally occurring variation of some stress metabolites involved in resistance traits to abiotic and biotic stresses in collaboration with different laboratories. We identify natural compounds which protect plants from stress. Through molecular approaches we improve the resistance of plants to different stresses.

Molecular pharming

We produce proteins of pharmaceutical interest in plants and study ways to improve their productivity under different environments to adapt to the requirements of local climates.


For a more detailed view of our research, have a look at our Research Projects and Scientific Publications sections.
For general public information have a look at +info.


News and Announcements e-Board

JOB OFFERS

NEW
A 3-years PhD position (2015-2017) is available in our laboratory to study 
Arabidopsis NB-LRR evolution and interactions with Hyaloperonospora arabidopsidis pathogens.

Interested candidates should send us their CV and two letters of reference by e-mail.

Questions should be addressed to the same e-mail address below.

Application period: 1 July - 15 September 2014

Expected starting date: January 2015

Contact



LATEST PUBLICATIONS

Editorial article of upcoming e-book in Frontiers in Plant Science. Editors: Ruben Alcazar & A.F. Tiburcio.
Plant polyamines in stress and development: an emerging area of research in plant sciences 
The Roles of Polyamines during the lifespan of plants:from development to stress
Tiburcio AF, Altabella T, Bitrián M and Alcázar R. (2014) Planta 240: 1-18.






The Faculty | The University | The Campus | Scientific and Technological Centers




Full address: Facultat de Farmacia, Universitat de Barcelona, Unitat de Fisiologia Vegetal. Avda Joan XXIII 27-31, 08028 Barcelona (Spain).
Tel +34 934 024 492 Fax +34 934 029 043

This wiki site is built under Openwetware, an open access movement promoting the sharing of information among researchers.

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