AhmadWeek5: Difference between revisions

Revision as of 20:18, 14 February 2013

Which of these genes has a homolog (similar gene related by descent) in humans? What disease does a deficiency of this gene cause in humans?
- GDH2; the homologs are GLUD1 and GLUD2. "Deficiencies in the human homologs of glutamate dehydrogenase, GLUD1 and GLUD2, have been linked to hyperinsulinism-hyperammonemia syndrome and various neurological disorders." GDH2
How is the expression of each of these genes regulated?
- GDH1- Expression is "regulated by nitrogen and carbon sources" GDH1
- GDH3-

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 {{Salman Ahmad}}
+==<i>Saccharomyces</i> Genome Database==
+#Which of these genes has a homolog (similar gene related by descent) in humans? What disease does a deficiency of this gene cause in humans?
+#*GDH2; the homologs are GLUD1 and GLUD2. "Deficiencies in the human homologs of glutamate dehydrogenase, GLUD1 and GLUD2, have been linked to hyperinsulinism-hyperammonemia syndrome and various neurological disorders." [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=GDH2 GDH2]
+#How is the expression of each of these genes regulated?
+#*GDH1- Expression is "regulated by nitrogen and carbon sources" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=gdh1 GDH1]
+#*GDH3-