AhmadWeek5

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{{Salman Ahmad}}
 
==<i>Saccharomyces</i> Genome Database==
==<i>Saccharomyces</i> Genome Database==
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#How is the expression of each of these genes regulated?
#How is the expression of each of these genes regulated?
#*GDH1- Expression is "regulated by nitrogen and carbon sources" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=gdh1 GDH1]
#*GDH1- Expression is "regulated by nitrogen and carbon sources" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=gdh1 GDH1]
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#*GDH3-
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#*GDH3- Expression is "regulated by nitrogen and carbon sources" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=gdh3 GDH3]
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#*GDH2- Expression is "sensitive to nitrogen catabolite repression and intracellular ammonia levels" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=GDH2 GDH2]
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#*GLN1- Expression is "regulated by nitrogen source and by amino acid limitation" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=gln1 GLN1]
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#*GLT1- Expression is "regulated by nitrogen source" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=glt1 GLT1]
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{{Salman Ahmad}}

Revision as of 23:24, 14 February 2013

Saccharomyces Genome Database

  1. Which of these genes has a homolog (similar gene related by descent) in humans? What disease does a deficiency of this gene cause in humans?
    • GDH2; the homologs are GLUD1 and GLUD2. "Deficiencies in the human homologs of glutamate dehydrogenase, GLUD1 and GLUD2, have been linked to hyperinsulinism-hyperammonemia syndrome and various neurological disorders." GDH2
  2. How is the expression of each of these genes regulated?
    • GDH1- Expression is "regulated by nitrogen and carbon sources" GDH1
    • GDH3- Expression is "regulated by nitrogen and carbon sources" GDH3
    • GDH2- Expression is "sensitive to nitrogen catabolite repression and intracellular ammonia levels" GDH2
    • GLN1- Expression is "regulated by nitrogen source and by amino acid limitation" GLN1
    • GLT1- Expression is "regulated by nitrogen source" GLT1


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