AhmadWeek5: Difference between revisions
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Salman Ahmad (talk | contribs) (answered the first couple questions, checking template) |
Salman Ahmad (talk | contribs) (added reactome pathway) |
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==<i>Saccharomyces</i> Genome Database== | ==<i>Saccharomyces</i> Genome Database== | ||
#Which of these genes has a homolog (similar gene related by descent) in humans? What disease does a deficiency of this gene cause in humans? | #Which of these genes has a homolog (similar gene related by descent) in humans? What disease does a deficiency of this gene cause in humans? | ||
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#How is the expression of each of these genes regulated? | #How is the expression of each of these genes regulated? | ||
#*GDH1- Expression is "regulated by nitrogen and carbon sources" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=gdh1 GDH1] | #*GDH1- Expression is "regulated by nitrogen and carbon sources" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=gdh1 GDH1] | ||
#*GDH3- | #*GDH3- Expression is "regulated by nitrogen and carbon sources" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=gdh3 GDH3] | ||
#*GDH2- Expression is "sensitive to nitrogen catabolite repression and intracellular ammonia levels" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=GDH2 GDH2] | |||
#*GLN1- Expression is "regulated by nitrogen source and by amino acid limitation" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=gln1 GLN1] | |||
#*GLT1- Expression is "regulated by nitrogen source" [http://www.yeastgenome.org/cgi-bin/locus.fpl?locus=glt1 GLT1] | |||
#"L-glutamate". How many pathways does it participate in? | |||
#*It is in reactions as a reactant 26 times. It is in reactions as a product 29 times. [http://pathway.yeastgenome.org/YEAST/new-image?type=COMPOUND&object=GLT L-glutamate] | |||
[[Image:LglutamatePathway.gif]] | |||
[http://pathway.yeastgenome.org/YEAST/NEW-IMAGE?type=PATHWAY&object=PWY3O-13&detail-level=3 Pathway Image Source] | |||
==Kegg== | |||
[[Image:KeggPathway.jpg]] | |||
[http://www.kegg.jp/kegg-bin/show_pathway?sce00250 Pathway Image Source] | |||
*Kegg shows both the full amino acid sequence and full nucleotide sequence when you click on the enzyme name. SGD did not show this. | |||
==Reactome== | |||
[[Image:ReactomePathwayAhmad.jpg]] | |||
[http://www.reactome.org/entitylevelview/PathwayBrowser.html#DB=gk_current&FOCUS_SPECIES_ID=68322&FOCUS_PATHWAY_ID=2666285&ID=2659868&VID=6541595 Reactome Source] | |||
{{Salman Ahmad}} |
Latest revision as of 23:54, 14 February 2013
Saccharomyces Genome Database
- Which of these genes has a homolog (similar gene related by descent) in humans? What disease does a deficiency of this gene cause in humans?
- GDH2; the homologs are GLUD1 and GLUD2. "Deficiencies in the human homologs of glutamate dehydrogenase, GLUD1 and GLUD2, have been linked to hyperinsulinism-hyperammonemia syndrome and various neurological disorders." GDH2
- How is the expression of each of these genes regulated?
- GDH1- Expression is "regulated by nitrogen and carbon sources" GDH1
- GDH3- Expression is "regulated by nitrogen and carbon sources" GDH3
- GDH2- Expression is "sensitive to nitrogen catabolite repression and intracellular ammonia levels" GDH2
- GLN1- Expression is "regulated by nitrogen source and by amino acid limitation" GLN1
- GLT1- Expression is "regulated by nitrogen source" GLT1
- "L-glutamate". How many pathways does it participate in?
- It is in reactions as a reactant 26 times. It is in reactions as a product 29 times. L-glutamate
Kegg
- Kegg shows both the full amino acid sequence and full nucleotide sequence when you click on the enzyme name. SGD did not show this.
Reactome
Assignments
- Class Journal Week 1
- Journal Assignment Week 2
- Class Journal Week 2
- Journal Assignment Week 3
- Class Journal Week 3
- Journal Assignment Week 4
- Class Journal Week 4
- Journal Assignment Week 5
- Class Journal Week 5
- Journal Assignment Week 6
- Class Journal Week 6
- Journal Assignment Week 8
- Class Journal Week 8
- Journal Assignment Week 9
- Class Journal Week 9
- Journal Assignment Week 11
- Class Journal Week 11
- Journal Assignment Week 12
- Class Journal Week 12
- Journal Assignment Week 13
- Class Journal Week 13
- Assignment Week 13
- Journal Assignment Week 14
- Class Journal Week 14
- Assignment Week 14