7.342:Schedule

Date	Discussion Leader	Topic
September 7	Matt/Roshan	Introduction
September 14	Roshan	Chromatin Functions to Define Cell State
September 21	Matt	Chromatin Structure and Discovery of Chromatin Modifying Enzymes
September 28	Matt	Methylation and the Emergence of the "Histone Code"
October 5	Matt	Heritable Gene Expression via Epigenetic Modification of Chromatin
October 12	Roshan	Regulators of Pluripotency and Differentiation of Stem Cells
October 19 (tentative)		Tour of Novartis Institute for Biomedical Research Laboratories
October 26	Matt	Regulation of Early Development by Polycomb Proteins
November 2	Roshan	Master Regulators of Differentiation: The Story of MyoD
November 9	Roshan	Chromatin Modifications during Development
November 16	Roshan	Transdifferentiation, Dedifferentiation, and the Adoption of Alternate Cell Fates
November 23		Thanksgiving!
November 30	Matt	When Regulators go Bad: Misregulation of Chromatin Modifiers in Cancer
December 7	Matt/Roshan	Oral Presentation of Research Proposals