3D printing in the life sciences: Difference between revisions

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(milestones of 3D bioprinting)
(milestones of 3D bioprinting)
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With technical improvements and increased affordability, 3D printing is fast gaining importance in the life science. For a graphical overview of the history of 3D printing see the [http://www.dipity.com/cmclellan/The-History-of-3D-Printing/ timeline].
With technical improvements and increased affordability, 3D printing is fast gaining importance in the life science. For a graphical overview of the history of 3D printing see the [http://www.dipity.com/cmclellan/The-History-of-3D-Printing/ timeline].


== 3D printing molecules ==
== 3D printing molecules & cells ==
* 2012 sugar scaffold for cell structuring
* 2000 - first pilot experiments with modified inkjet printers
: Boland & colleagues attempt to deposit proteins & cells in 2D patterns
 
* 2002 - artificial kidney (not functional) by Wake Forest University School of Medicine
: It is occasionally claimed (for example in the timeline above) that a working kidney was 3D printed in 2002. Cells were indeed 3D printed but the organ was not functional since it lacked working blood supply and urine drainage.
 
* 2004 - Forgacs & colleagues develop cell droplet printing (bioink)
: Nozzles much wider than those of an inkjet allow for 3D deposition (circles & tubes) of clusters of cells with support of a gel. This technology is the basis of the company Organovo.
 
* 2012 - sugar scaffold for cell structuring
: Jordan Miller & colleagues develop a method to use 3D printed to scaffold cells ([http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586565/ Miller12])
: Jordan Miller & colleagues develop a method to use 3D printed to scaffold cells ([http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586565/ Miller12])


 
* 2014 - 3D printed slices of liver tissue for testing
== 3D printing cells ==
* 2002 artificial kidney (not functional)
: It is occasionally claimed (for example in the timeline above) that a working kidney was 3D printed in 2002. Cells were indeed 3D printed but the organ was not functional since it lacked working blood supply and urine drainage.
* 2014 3D printed slices of liver tissue for testing
: Organovo delivers the first [http://organovo.com/tissues-services/exvive3d-human-tissue-models-services-research/exvive3d-liver-tissue-performance/ 3D printed slices of liver tissue] for preclinical testing to pharmaceutical companies
: Organovo delivers the first [http://organovo.com/tissues-services/exvive3d-human-tissue-models-services-research/exvive3d-liver-tissue-performance/ 3D printed slices of liver tissue] for preclinical testing to pharmaceutical companies



Revision as of 07:41, 15 April 2016

Prototype of a gel bioprinter generating a tube that can be implanted for controlled drug release (video)

With technical improvements and increased affordability, 3D printing is fast gaining importance in the life science. For a graphical overview of the history of 3D printing see the timeline.

3D printing molecules & cells

  • 2000 - first pilot experiments with modified inkjet printers
Boland & colleagues attempt to deposit proteins & cells in 2D patterns
  • 2002 - artificial kidney (not functional) by Wake Forest University School of Medicine
It is occasionally claimed (for example in the timeline above) that a working kidney was 3D printed in 2002. Cells were indeed 3D printed but the organ was not functional since it lacked working blood supply and urine drainage.
  • 2004 - Forgacs & colleagues develop cell droplet printing (bioink)
Nozzles much wider than those of an inkjet allow for 3D deposition (circles & tubes) of clusters of cells with support of a gel. This technology is the basis of the company Organovo.
  • 2012 - sugar scaffold for cell structuring
Jordan Miller & colleagues develop a method to use 3D printed to scaffold cells (Miller12)
  • 2014 - 3D printed slices of liver tissue for testing
Organovo delivers the first 3D printed slices of liver tissue for preclinical testing to pharmaceutical companies

3D printing models of biomolecules

See also