20.109(S09)/PinkWF
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Our goal is to rewire a bacterium to "miniprep" itself, when given some sort of an external stimuli (such as sensing of dense cell growth). This project will serve the following purposes: | Our goal is to rewire a bacterium to "miniprep" itself, when given some sort of an external stimuli (such as sensing of dense cell growth). This project will serve the following purposes: | ||
| - | + | * Make the research process easier, cheaper, and more efficient for scientists working with bacteria. | |
| - | + | * Most laboratory strains have been genetically modified for scientific use; however our bacteria would be the first to be modified to do an experiment on itself. | |
| - | + | * Self-lysing of cells when dense cell growth is encountered - less chance for environmental contamination if genetically engineered bacteria escape from the lab | |
| - | + | * Serve as an example of a way synthetic biology can be used for cellular control | |
| - | + | * Be an application of using irreversible switches within genetic circuits | |
| - | + | * Be an example of sensors being built into bacteria | |
==Background== | ==Background== | ||
Revision as of 02:40, 5 May 2009
Contents |
20.109 Research Proposal for Derek Ju and Alvin Chen
Project Overview
Our goal is to rewire a bacterium to "miniprep" itself, when given some sort of an external stimuli (such as sensing of dense cell growth). This project will serve the following purposes:
- Make the research process easier, cheaper, and more efficient for scientists working with bacteria.
- Most laboratory strains have been genetically modified for scientific use; however our bacteria would be the first to be modified to do an experiment on itself.
- Self-lysing of cells when dense cell growth is encountered - less chance for environmental contamination if genetically engineered bacteria escape from the lab
- Serve as an example of a way synthetic biology can be used for cellular control
- Be an application of using irreversible switches within genetic circuits
- Be an example of sensors being built into bacteria
