20.109(F12) Pre-Proposal: Viral mitigation of insulin resistance: Difference between revisions
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*Why is this field important | *Why is this field important | ||
==Your idea== | ==Your idea== | ||
Personal health is of great concern to today's society, especially in relation to weight loss. | Personal health is of great concern to today's society, especially in relation to weight loss. The rate of Type 2 diabetes in the human population has increased alongside the rate of obesity; it has been clear for some time that excessive weiht gain | ||
==A sketch== | ==A sketch== | ||
[[Image:Preproposal_Diagram.jpg]] | [[Image:Preproposal_Diagram.jpg]] | ||
Revision as of 02:57, 29 November 2012
Investigators
- Stanley Gill
- Amy Liu
- T/R 20.109 Lab
- Team Yellow
Title of Proposed Project
Antibody-based Regulation of Resistin Levels through a Synthetic Circuit Injected via Vector Immunoprophylaxis
Project Summary
One of the hallmark characteristics of obesity and Type 2 diabetes is insulin resistance. Resistin, a peptide produced by endocrine adipocytes in mice, has been implicated in increasing the likelihood of insulin resistance and is present in high levels in the blood of obese patients. Here, we explore that the introduction of a regulated synthetic system that produces antibodies against resistin may stave off insulin resistance, alleviating and preventing the development of Type 2 diabetes.
Introduction
ONE PARAGRAPH and at least TWO REFERENCES
- What is known about this field
- Why is this field important
Your idea
Personal health is of great concern to today's society, especially in relation to weight loss. The rate of Type 2 diabetes in the human population has increased alongside the rate of obesity; it has been clear for some time that excessive weiht gain
A sketch
