20.109:WFYProposal

=20.109 Research Proposal, WF Yellow Grouop=

Problem
Find a 19S proteasome subunit protein that will bind a the Amaloid Beta protein responsible for Amaloid plaques in Alzheimer's disease and target it for degredation.

Proteasome

 * Tania A. Baker and Robert T. Sauer. ATP-dependent proteases of bacteria: recognition logic and operating principles. TRENDS in Biochemical Sciences 2006; 31 (12) 647.