MES

2--(N-morpholino)ethanesulfonic acid, CAS 4432-31-9 Good66,Good74,Blanchard84. Stable pH vs. temperature, no primary amine groups, no metal chelation, near physiologic pH range.


 * pKa at 25°C of 6.10 (5.97 at 37°C)
 * usable buffering range of 5.5 to 6.7
 * molecular weight 195.24
 * &Delta;pKa/&Delta;T = -.011

Buffers are typically 1 M, prepared by neutralizing MES with sodium hydroxide.


 * 1) Good66 pmid=5942950
 * 2) Good74 pmid=4206745
 * 3) Blanchard84 pmid=6717292

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