20.109(F08):Anna YingFei Module3

Anna's and YingFei's Research Proposal
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Using Cysteine-Knot Proteins to Engineer Drugs for Cancer Treatment
Papers we are using as resources:









Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2

Grafting of thrombopoietin-mimetic peptides into cystine knot miniproteins yields high-affinity thrombopoietin antagonists and agonists 

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability 

Cyclotides: A Novel Type of Cytotoxic Agents