Imperial College/Courses/Spring2008/Synthetic Biology/Computer Modelling Practicals/Practical 2/Report

   Practical 2: Report Structure


 * Name:
 * Department:

 Part I: Constitutive Gene Expression
 * 1) [mRNA] expression when at steady state, [Protein] expression when at steady state
 * 2) average transcription rate, average translation rate
 * 3) Simulation output
 * 4) Sensitivity Analysis on the protein steady state with regards to the 4 parameters (parameter scan outputs)
 * 5) under quasi-steady-state assumption on [mRNA], expression of 's' and 'd'
 * 6) model comparison: illustration + comments.

 Part II: Activated and Repressed Gene Expression
 * 1) transfer function graph for the repressor circuit
 * 2) possible application of the repressor circuit
 * 3) transfer function graph for the activator circuit
 * 4) possible application of the activator circuit

 Part III: Feedback Gene Expression
 * 1) Provide ODEs system for the 3 circuits
 * 2) Model comparison with illustrations + comments