SLokwong; saga mod 3

{| border="1" ! Ada subunits ! size,chromosome,null p-type ! notes
 * Ada1 (aka HFI1, SUP110, SRM12, GAN1)
 * 1.467 kb/489 aa, Chr. XVI, viable
 * ==gene product==
 * ==gene product==

systematic deletion
transcriptional coactivator
 * Ada2 (aka SWI8)
 * 1.305 kb/434aa, Chr. IV, viable
 * ==gene product==: Ada histone acetyltransferase complex component,
 * ==gene product==: Ada histone acetyltransferase complex component,

molecular function

 * transcription coactivator activity (TAS)

systematic deletion

 * viable
 * decreased drug resistance (rapamycin)
 * decreased drug resistance (wortmannin)
 * Ada3(aka NGG1, SWI7)
 * 2.109 kb/702aa, Chr. IV, viable
 * ==gene product==
 * 2.109 kb/702aa, Chr. IV, viable
 * ==gene product==

systematic deletion

 * Gcn5 (aka ADA4, SWI9)
 * 1.32 kb/439aa, Chr. VII, viable
 * ==gene product== Ada histone acetyltransferase complex component
 * ==gene product== Ada histone acetyltransferase complex component

molecular function

 * histone acetyltransferase activity (IDA)
 * transcription coactivator activity (TAS)

systematic deletion
{| border="1" ! Spt subunits ! size, chromosome, null p-type ! notes
 * reduced fitness in rich medium (YPD)
 * Ada5 (aka SPT20)
 * 1.815 kb/604aa, Chr. XV, viable
 * same as SPT20
 * }
 * }
 * Spt3
 * 1.014 kb/337aa, Chr. IV, viable
 * ==gene product==
 * ==gene product==

systematic deletion
transcription factor
 * Spt7(aka GIT2)
 * 3.999 kb/1332aa, Chr. II, viable
 * ==gene product== histone acetyltransferase SAGA complex member
 * ==gene product== histone acetyltransferase SAGA complex member

molecular function
* structural molecule activity (IDA, IMP)

systematic deletion

 * viable
 * increased drug resistance (rapamycin)
 * decreased drug resistance (wortmannin)
 * Spt8
 * 1.809 kb/602aa, Chr. XII, viable
 * ==gene product== transcription factor
 * ==gene product== transcription factor

molecular function

 * TATA-binding protein binding (IDA, IMP)
 * transcription cofactor activity (IMP, IPI)

Systematic deletion
transcription factor
 * viable
 * Exhibits sensitivity at 5 generations when grown in synthetic complete - trp medium.
 * normal chitin levels
 * increased drug resistance (rapamycin)
 * decreased drug resistance (wortmannin)
 * Spt20 (aka Ada5)
 * 1.815 kb/604aa, Chr. XV, viable
 * ==gene product== histone acetyltransferase SAGA complex member
 * ==gene product== histone acetyltransferase SAGA complex member

molecular function
transcription cofactor activity (IGI, IMP, IPI)

systematic deletions
{| border="1" ! TAF subunits ! size, chromosome, null p-type ! notes
 * decreased drug resistance (rapamycin)
 * decreased drug resistance (wortmannin)
 * }
 * TAF5 (aka TAF90)
 * 2.397 kb/798aa, Chr. II, inviable
 * ==gene product==
 * ==gene product==

systematic deletion
TafII60
 * TAF6 (aka TAF60)
 * 1.551 kb/516aa, Chr. VII, inviable
 * ==gene product== TATA-binding protein-associated-factor
 * ==gene product== TATA-binding protein-associated-factor

molecular function
* general RNA polymerase II transcription factor activity (TAS)

systematic deletion
* inviable TafII17
 * TAF9 (aka TAF17)
 * 0.474 kb/157aa, Chr. XIII, inviable
 * ==gene product== 	TFIID subunit
 * ==gene product== 	TFIID subunit

molecular function
* general RNA polymerase II transcription factor activity (TAS)

systematic deletion
* inviable TafII25
 * TAF10 (aka TAF23, TAF25)
 * 0.621 kb/206aa, Chr. IV, inviable
 * ==gene product== TFIID subunit
 * ==gene product== TFIID subunit

molecular function
* general RNA polymerase II transcription factor activity (TAS)

systematic deletion
* inviable TafII61 TafII68
 * TAF12(aka TAF61, TAF68)
 * 1.620 kb/539aa, Chr. IV, inviable
 * ==gene product== 	 	TFIID subunit
 * ==gene product== 	 	TFIID subunit

molecular function
* general RNA polymerase II transcription factor activity (TAS)

systematic deletion
inviable {| border="1" ! Tra1 subunit ! size, chromosome, null p-type ! notes
 * }
 * Tra1
 * 11.235 kb/3744aa, Chr. VIII, inviable
 * Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation (1, 2, 3, 4)
 * Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation (1, 2, 3, 4)

systematic deletion
{| border="1" ! other subunits ! size, chromosome, null p-type ! notes
 * }
 * Sgf73
 * 1.974 kb/657aa, Chr. VII, viable
 * 3 kDa subunit of SAGA histone acetyltransferase complex; involved in formation of the preinitiation complex assembly at promoters (1, 3)
 * 3 kDa subunit of SAGA histone acetyltransferase complex; involved in formation of the preinitiation complex assembly at promoters (1, 3)

systematic deletion
viable
 * Sgf29
 * 0.779 kb/259aa, Chr. III, viable
 * SaGa associated Factor 29kDa; Probable 29kKDa Subunit of SAGA histone acetyltransferase complex (1)
 * SaGa associated Factor 29kDa; Probable 29kKDa Subunit of SAGA histone acetyltransferase complex (1)

systematic deletion
viable
 * Exhibits sensitivity at 15 generations when grown in medium of pH 8.
 * Sgf11
 * 0.3 kb/99aa, Chr.XVI, viable
 * Integral subunit of SAGA histone acetyltransferase complex, regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation (1, 2)
 * Integral subunit of SAGA histone acetyltransferase complex, regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation (1, 2)

systematic deletion
viable
 * Ubp8
 * 1.416 kb/471aa, Chr. XIII, viable
 * Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B (1, 2)
 * Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B (1, 2)

systematic deletion
viable
 * Sus1
 * gene with intron, Chr. II, viable
 * Protein involved in mRNA export coupled transcription activation; component of the SAGA histone acetylase complex (1)
 * Protein involved in mRNA export coupled transcription activation; component of the SAGA histone acetylase complex (1)

systematic deletion

 * }