CHE.496/2008/Assignments

Assignment 1: Synthetic biology overview

 * 1) '''Intelligent Design link
 * 2) '''Extreme genetic engineering: an introduction to synthetic biology link

Assignment 2: Foundational technologies

 * 1) '''Foundations for engineering biology link
 * 2) '''Synthetic biology: promises and challenges link
 * 3) '''The iGEM competition: building with biology link

Assignment 3: Engineering principles

 * 1) '''Synthetic biology - putting engineering into biology link
 * 2) '''Synthetic biology: new engineering rules for an emerging discipline link

Assignment 4: Genetic programming

 * 1) '''Idempotent vector design for standard assembly of biobricks link
 * 2) '''Genetic parts to program bacteria link

Assignment 5: Natural biological parts

 * 1) '''Another side of genomics: Synthetic biology as a means for the exploitation of whole-genome sequence information link
 * 2) '''Codon bias and heterologous protein expression link

Assignment 6: Practical applications

 * 1) '''Advances in synthetic biology: on the path from prototypes to applications link
 * 2) '''Molecular switches for cellular sensors link

Assignment 7: Social implications

 * 1) '''The promises and perils of synthetic biology link
 * 2) '''DNA synthesis and biological security link

Assignment 8: Engineering biology

 * 1) '''A partnership between biology and engineering link
 * 2) '''Fast, cheap and somewhat in control link

Assignment 9: Biological machines

 * 1) '''Designing biological systems link
 * 2) '''Biology by design: Reduction and synthesis of cellular components and behavior link

Assignment 10: Genetic circuit engineering (part 1)

 * 1) '''A synthetic oscillatory network of transcriptional regulators link
 * 2) 'Construction of a genetic toggle switch in Escherichia coli'' link

Assignment 11: Genetic circuit engineering (part 2)

 * 1) '''Environmentally controlled invasion of cancer cells by engineered bacteria link
 * 2) '''Environmental signal integration by a modular AND gate link

Assignment 12: Metabolic pathway engineering

 * 1) '''Bioengineering novel in vitro metabolic pathways using synthetic biology link
 * 2) '''Synthetic biology for synthetic chemistry link

Assignment 13: Systems biology and synthetic biology

 * 1) '''Systems biology as a foundation for genome-scale synthetic biology link
 * 2) '''Modular approaches to expanding the functions of living matter link

Assignment 14: Biological networks

 * 1) '''Biological networks link
 * 2) '''Programming and engineering biological networks link

Assignment 15: RNA synthetic biology

 * 1) '''RNA synthetic biology link
 * 2) '''RNA and RNP as new molecular parts in synthetic biology link