User:Mbennie/Notebook/Papers and Books/Applications

Controlled-Invasion pmid=16330045
 * Used invasin to target tumor cells using factors such as hypoxia and bacteria's natural tendency to grow in regions of high cell density
 * Mammalian cells normally take up a cell with invasin
 * Used directed evolution to find strains that worked according to their parameters: invasion under certain condition and no invasion otherwise

Organ-targeting pmid=8598934
 * Isolated phage that were targeted towards specific organs by repeated injection and recovery
 * Found phage that were 8 times more targeted towards the kidneys or brain

Cols-Secretion pmid=11545269
 * Attempts to express MT in e coli and secreted into media in order to bind Cu
 * MT is a really cool protein (binds several types of heavy metals)
 * Hypothesized that metal binds to MT inside of cell, but in periplasm metal release when disulfide bridge is formed
 * Removed 34% of Cu using best plasmid