IGEM:Stanford/2009/Groups/Team CAM/microbots


 * Benefits of Bactofection by Microbots
 * Krusch J Gene 2003
 * Riboswitches [Anusuya Ramasubramanian]
 * Why Riboswitches?
 * Characterize input/output signal
 * What riboswitch would you use?
 * What signaling molecule would you use
 * Surface Protein Expression (B+J)
 * What other bacterial surface receptors exist?
 * Look into InlB Hamon Nat Rev Micro 2006
 * What antigens are unique to cancer cells?
 * Nanoparticle production (B+J)
 * Read supplement of Akin Nat Nano 2007
 * Costs? Difficulty?
 * Model Organisms [Mark Fang]
 * What human cell lines do we need?
 * What vector would we use
 * Why?
 * L. monocytogenes?
 * Krusch J Gene 2003
 * Pilgrim Gene Ther 2002
 * Safety? Angelakopoulos Infect Immun 2002
 * Ecoli?
 * Bactofection by E.coli
 * Larsen Gene Ther 2008
 * Previous iGEM Projects
 * Bacteria targeting Harvard 07
 * Safe Bacterium Bactoblood 07
 * Killing phage Heidelberg 08
 * Riboswitches Melbourne 08
 * Making new receptors Sheffield 08
 * Gene delivery to yeast U Washinton 08
 * http://openwetware.org/images/0/00/Visualization_of_tumors_and_metastases_in_live_animals_with_bacteria_and_vaccinia_virus.pdf