IGEM:MIT/2005/Future direction


 * What we have done:
 * Make a modular tool
 * Input any external signal in a controlled manner
 * How to improve:
 * Modularity
 * ToxR needs to be "extended to outer membrane
 * Test with primary and secondary antibody setup
 * Use antigen that is not already a dimer
 * Test modularity by using different antigens, signal processing systems and actuators
 * Usability
 * Activity must be characterized
 * Could be tested in other chassis
 * Feedback mechanisms and other downstream stuff to demonstrate usability
 * System Applications:
 * Biosensor
 * environmental application -- test for contaminates
 * Research tools
 * Replace other antibody sensors (western blots), cell-cell signaling
 * Long term impact
 * extending and easing research in synthetic biology