User:Remant Bahadur K.c.

Contact Info

 * Department of Pharmaceutical and Biomedical Sciences


 * South Carolina College of Pharmacy*
 * University of South Carolina
 * 715 Sumter St. CLS 616, Columbia SC 29208
 * Phone: 1-803-777-7101 (Office), 1-803-397-8078 (Cell)
 * E-mail: RemantKC@sccp.sc.edu

Education

 * 2004 - 2007       Ph.D., Department of Bionanosystem    Engineering, Chonbuk National University Korea
 * 1999 - 2001       M.Sc., Central Department of Chemistry, Tribhuvan University, Kathmandu, Nepal
 * 1996 - 1999       B.Sc., Department of Chemistry, Trichndra Multiple Campus, Tribhuvan University, Kathmandu, Nepal
 * 1994 - 1996       I.Sc., Tribhuvan Multiple Campus, Tribhuvan University

Research interests
My research experience reflects a multidisciplinary expertise in material design for drug/gene delivery and nanoengineering
 * RESEARCH EXPERIENCE

Currently I am working on the design of degradable dendrimers for gene and drug delivery. It ranges from design and characterization of polymers and controlled/targeted delivery of drugs (Doxorubicin)/genes (siRNA) to the cancer cells. By this project I would like to upgrade my research on therapeutic efficacy of the designed materials via in-vitro and in-vivo experiment
 * CURRENT RESEARCH

Publications

 * PEER-REVIEWED ARTICLES
 * 1) Remant Bahadur K.C., Breanne Landry, Afsaneh Lavasanifar, Hasan Uludağ, Lipid-Substitution on Low Molecular Weight Polyethylenimine Leads to Effective Assembly of Plasmid DNA and Transgene Expression, Acta Biomaterialia
 * 2) Hamidreza Montazeri Aliabadi, Breanne Landry, Remant Bahadur K. C., Artphop Neamnark, Orawan Suwantong, Hasan Uludağ, Impact of Lipid-Substitution on Assembly and Delivery of siRNA by Cationic Polymers, Macromolecular Bioscience (2011, In Press).
 * 3) Remant Bahadur K.C., Hasan Uludağ, A Comparative Evaluation of Disulfide-Linked and Hydrophobically-Modified PEI for Plasmid Delivery, Journal of Biomaterial Science: Polymer Edition, 22 (2011) 873–892.
 * 4) Wujie Zhang, Kyle Gilstrap, Laying Wu, Remant Bahadur K.C., Qian Wang, Xiongbin Lu, and Xiaoming He, Synthesis and characterization of thermally responsive Pluronic-chitosan nanocapsules for controlled release and intracellular delivery of small molecules, ACS NANO, 4 (2010) 6747-6759.
 * 5) Artphop Neamnark, Orawan Suwantong, Remant Bahadur K.C., Charlie Y.M. Hsu, Pitt Supaphol, and Hasan Uludað, Aliphatic Lipid Substitution on 2 kDa-Polyethylenimine Improves Plasmid Delivery and Transgene Expression, Molecular Pharmaceutics, 6 (2009) 1798-1815.
 * 6) Shanta Raj Bhattarai, Remant Bahadur K.C., Sun Yong Kim, Myung Seob Khil, Pyong Han Hwang, Gyung Ho Chung, Hak Yong Kim and Manju Sharma, N-hexanoyl Chitosan Stabilized Magnetic Nanoparticles: Implication for Cellular Labeling and Magnetic Resonance Imaging, Journal of Nanobiotechnology (In Press).
 * 7) Remant Bahadur K.C., So Min Lee, Eun Soo Yoo, Han Do Ghim, Glycoconjugated Chitosan Stabilized Iron Oxide Nanoparticles as a Multifunctional Nanoprobe, Material Science and Engineering C, 29 (2009) 1668-1673.
 * 8) Madhab Prasad Bajgai, Santosh Aryal, Shanta Raj Bhattarai, Remant Bahadur K. C, Kawn-Woo Kim, and Hak Yong Kim, “Poly (α- caprolactone) Grafted Dextran Biodegradable Electrospun Matrix: A Novel Scaffold for Tissue Engineering”, Journal of Applied Polymer Science 108 (2008)1447–1454.
 * 9) Remant Bahadur K.C., Chul Ki Kim, Myung Seob Khil, Ick Soo Kim, Hak Yong Kim. Synthesis of Hydroxyapatite Crystals Using Titanium oxide Electrospun nanofibers, Material Science and Engineering C 28 (2008) 70-74.
 * 10) Shanta Raj Bhattarai, Santosh Aryal, Remant Bahadur K. C., Narayan Bhattarai, Pyoung Han Hwang, Ho Keun Yi, and Hak Yong Kim. Carbon Nanotube-Hydroxyapatite Nanocomposite as a Nano Carrier for DNA. Material Science and Engineering C 28 (2008) 64-69.
 * 11) Shanta Raj Bhattarai, Remant Bahadur K.C., Santosh Aryal, Narayan Bhattarai, Sun Young Kim, Ho Keun Yi, Pyoung Han Hwang and Hak Yong Kim. Hydrophobically modified chitosan/gold nanoparticles for DNA delivery Journal of Nanoparticle Research 10 (2008) 151-162.
 * 12) Remant Bahadur K.C., Kwan-Woo Kim, Shanta Raj Bhattarai, Hak Yong Kim. Effect of Collector Temperature and Conductivity on the Chain Conformation of Nylon 6 Electrospun Nanofibers Polymer and Fiber 8 (2007) 186-191.
 * 13) Santosh Aryal, Remant Bahadur K.C., Myung Seob Khil, N. Dharmaraj,and Hak Yong Kim. Radical scavenger for the stabilization of gold nanoparticles. Materials Letters 61 (2007) 4225-4230.
 * 14) Shanta Raj Bhattarai, Remant Bahadur K.C., Santosh Aryal, Myung Seob Khil, and Hak Yong Kim. N-acylated chitosan stabilized iron oxide nanoparticles as a novel nano-matrix and ceramic modification Carbohydrate polymer 69 (2007) 467– 477.
 * 15) Remant Bahadur K.C., Santosh Aryal, Shanta Raj Bhattarai, Myung Seob Khil, and Hak Yong Kim. Amphiphilic triblock Copolymer based on PPDO and PEG: Synthesis, Characterization and Aqueous dispersion. Journal of Applied Polymer Science 103 (2007) 2695–2702.
 * 16) Remant Bahadur K.C., Shanta Raj Bhattarai, Santosh Aryal, Narayan Bhattarai, Byoung Min Lee, Hak Yong Kim. Synthesis and characterization of amine functionalized amphiphilic block copolymer based on poly(ethylene glycol) and poly(α-caprolactone) Polymer International 56 (2007) 518–524.
 * 17) Remant Bahadur K.C., Shanta Raj Bhattarai, Santosh Aryal, Myung Seob Khil, N. Dharmaraj, and Hak Yong Kim. Novel Amphiphilic Triblock Copolymer Based on PPDO, PCL, and PEG: Synthesis, Characterization, and Aqueous Dispersion Colloids and Surfaces A: Physicochemical and Engineering Aspect 292 (2007) 69–78. [Selected as a Top 25 Hottest Articles, January to March 2007]
 * 18) Santosh Aryal, Shanta Raj Bhattarai, Remant Bahadur K.C., Myung Seob Khil uck Rae Lee and Hak Yong Kim. Carbon nantubes assisted biomimetic synthesis f hydroxyapatite from simulated body fluid. Material Science and Engineering A, 426 (2006) 202-207.
 * 19) Remant Bahadur K.C., Santosh Aryal, Narayan Bhattarai and Hak Yong Kim. Ceramic modification of N-acylated chitosan stabilized gold nanoparticles. Scripta Materialia 54 (2006) 2029-2034. [Selected as a Top 25 Hottest Articles, April to March 2006]
 * 20) Santosh Aryal, Remant Bahadur K.C., Narayan Bhattarai, Byoung Min Lee and Hak Yong Kim. Stabilization of gold nanoparticles by thiol functionalized poly(α- Caprolactone) for the labeling of PCL biocarrier. Materials Chemistry and Physics, 98 (2006) 463-469.
 * 21) Santosh Aryal, Remant Bahadur K.C., Narayan Bhattarai, Chul Ki Kim and Hak Yong Kim. Study of electrolyte induced aggregation of gold nanoparticles capped by amino acids. Journal of Colloid and Interface Science, 299 (2006) 191-197.
 * 22) Remant Bahadur K.C., Santosh Aryal, Shanta Raj Bhattarai, Narayan Bhattarai Chi Hun Kim, and Hak Yong Kim. Stabilization of gold nanoparticles by hydrophobically modified polycations. Journal of Biomaterial Science: Polymer Edition 17 (2006) 579-589.
 * 23) Santosh Aryal, Remant Bahadur K.C., Shanta Raj Bhattarai, P.Prabu and Hak Yong Kim. Immobilization of collagen on gold nanoparticles: preparation, characterization, and hydroxyapatite growth, Journal of Material Chemistry 16 (2006) 4642–4648.
 * 24) Santosh Aryal, Remant Bahadur K.C., N. Dharmaraj, Kawn-Woo Kim and Hak Yong Kim.Synthesis and characterization of hydroxyapatite using carbon nanotubes as a nano-matrix. Scripta Materialia, 54 (2006) 131-135.
 * 25) Santosh Aryal, Remant Bahadur K.C., N. Dharmaraj, Narayan Bhattarai, Chi Hun Kim and Hak Yong Kim. Spectroscopic identification of S-Au interaction in cysteine capped gold nanoparticles. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 63 (2006) 160-163.
 * LIST OF PATENTS
 * 1) Remant Bahadur K. C., Santosh Aryal, Kim H. Y. Methods of manufacturing Hydroxyapatite Nanocomposite. Korea Patent No. 10-0795345.
 * 2) Santosh Aryal, Remant Bahadur K. C., H. Y Kim. Hybrid Nanofiber and method of manufacturing for the same. Korea Patent No. 10-0739346.
 * 3) Santosh Aryal, Remant Bahadur K. C., H. Y Kim. Carbon Nanotube-Chitosan composites and method of manufacturing the same. Korea Patent No. 10-0702873.

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