Pruszak:Publications



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Original publications
1. K. Schlegelmilch*, M. Mohseni*, O. Kirak, J.Pruszak, J.R. Rodriguez, D. Zhou, B.T. Kreger, V. Vasioukhin, J. Avruch, T.R. Brummelkamp, F.D. Camargo: Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation.  Cell 2011 144(5):782-95. 2. J.E. Carette*, J.Pruszak*, M. Varadarajan, V.A. Blomen, S. Gokhale, F.D. Camargo, M. Wernig, R. Jaenisch, T.R. Brummelkamp: Generation of iPSCs from cultured human malignant cells.   Blood 2010 115(20):4039-42. * equal contribution 3. S. Chung, A. Leung, B.S Han, M.Y. Chang, J.I. Moon, C.H. Kim, S. Hong, J.Pruszak, O. Isacson, K.S. Kim: Wnt1-lmx1a Forms a Novel Autoregulatory Loop and Controls Midbrain Dopaminergic Differentiation Synergistically with the SHH-FoxA2 Pathway.  Cell Stem Cell 2009 5(6):646-58. 4. J.Pruszak, W. Ludwig, A. Blak, K. Alavian, O. Isacson: CD15, CD24 and CD29 define a surface biomarker code for neural lineage differentiation of stem cells.  Stem Cells 2009 27(12):2928-40. 5. J.Pruszak, L. Just, O. Isacson, G. Nikkhah: Isolation and culture of ventral mesencephalic precursor cells and dopaminergic neurons from rodent brains.  Current Protocols in Stem Cell Biology 2009 2D.5:1-21 6. H. Wakimoto, S. Kesari, C.J. Farrell, W.T. Curry WT, C. Zaupa, M. Aghi, T. Kuroda, A. Stemmer-Rachamimov, K. Shah, T.C. Liu, D.S. Jeyaretna, J. Debasitis, J.Pruszak, R.L. Martuza, S.D. Rabkin: Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Research 2009 69(8):3472-81. 7. M. Wernig, J.P. Zhao*, J.Pruszak*, E. Hedlund, D. Fu, F. Soldner, V. Broccoli, M. Constantine-Paton, O. Isacson, R. Jaenisch: Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. PNAS 2008 105(15):5856-61. * equal contribution 8. E.M. Hedlund, J.Pruszak, T. Lardaro, W. Ludwig, A. Viñuela, K.S. Kim, O. Isacson: Embryonic Stem (ES) Cell-derived Pitx3-eGFP Midbrain Dopamine Neurons Survive Enrichment by FACS and Function in an Animal Model of Parkinson's Disease. Stem Cells 2008 26(6):1526-36. 9. J.Pruszak, K.C. Sonntag, M.H. Aung, R. Sanchez-Pernaute, O. Isacson: Markers and Methods for Cell Sorting of Human Embryonic Stem Cell-derived Neural Cell Populations.  Stem Cells 2007 25(9):2257-68. 10. G. Brunlid, J.Pruszak, B. Holmes, O. Isacson, K.C. Sonntag: Immature and Neurally Differentiated Mouse ES Cells Do Not Express A Functional Fas/FasL System.  Stem Cells 2007 25(10):2551-8. 11. E. Hedlund, J.Pruszak, A. Ferree, A. Viñuela, S. Hong, O. Isacson, K.S.Kim: Selection of embryonic stem cell derived eGFP+ dopamine neurons using the tyrosine hydroxylase promoter is confounded by reporter gene expression in immature cell populations. Stem Cells 2007 25(5):1126-35. 12. K.C. Sonntag, J.Pruszak, T. Yoshizaki, J. van Arensbergen, R. Sanchez-Pernaute, O. Isacson: Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using the BMP antagonist noggin. Stem Cells 2007 25(2):411-8. 13. S. Chung, B.S. Shin, E. Hedlund, J.Pruszak, O. Isacson et al.: Genetic selection of sox1GFP-expressing neural precursors removes residual tumorigenic pluripotent stem cells and attenuates tumor formation after transplantation.   J. Neurochem. 2006 97(5):1467-80. 14. K.C. Sonntag, R. Simantov, L. Bjorklund, O. Cooper, J.Pruszak, F. Kowalke, J. Gilmartin, J. Ding, Y.P. Hu, M.M. Shen, O. Isacson: Context-dependent neuronal differentiation and germ layer induction in Smad-/- and Cripto-/- embryonic stem cells.   Mol. Cell. Neurosci. 2005 28(3):417-29.

Reviews, book chapters, etc.
15. J.Pruszak: [http://jama.ama-assn.org/content/304/2/218.extract Dissection: Photographs of a Rite of Passage in American Medicine: 1880-1930. (Book and Media Reviews)]  JAMA 2010 304:218-220 16. J.Pruszak, M. Dobrossy, J. Kieninger, K. Aravindalochanan, G.A. Urban, G. Nikkhah: Neural stem cells: from cell fate and metabolic monitoring toward clinical applications.  [in: Artmann, Minger & Hescheler (eds.): "Stem Cell Engineering: Principles and Applications",. 2010 435-456. 17. J.Pruszak, O. Isacson: Molecular and cellular determinants for generating ES-cell derived dopamine neurons for cell therapy.   Advances in Experimental Medicine and Biology. 2009 651:112-23. 18. J.Pruszak & O. Isacson: Directed Differentiation of Human Embryonic Stem Cells into Dopaminergic Neurons [in: Sullivan, Cowan & Eggan (eds.): "Human Embryonic Stem Cells: The Practical Handbook"; Wiley 2007] 19. S. Karki, J.Pruszak, O. Isacson, K. Sonntag: ES cell-derived neuroepithelial cell cultures Journal of Visualized Experiments, Issue 1, Nov. 2006. [Video Article]