Integrases/Excisionases pairs to test

We will start to test 3 pairs of the serine integrase family. Integrases from this family are interesting because they do not require specific cofactors and have been shown to work in a wide range of species. These 3 pairs are the best characterized members from the family which have an identified excisionase.



Bxb1
From Mycobacterium phage Bxb1.

Uniprot entry:

Bxb1 integrase     Bxb1 excisionase

References:

[1], [2], [3].


 * TP901-1

From Lactococcus lactis phage TP901-1.

Uniprot entries:

TP901-1 integrase     TP901-1 excisionase

Structure of the catalytic domain: [3BVP]

References: [4], [5], [6], [7].


 * phiRV1 [int: o06604, RDF: o06606]

From Mycobacterium tuberculosis prophage-like element phiRv1.

Uniprot entries:

phiRV1 integrase     phiRV1 excisionase

References: [8], [9]