Matt Gethers/20.310 Term Paper

=20.310 Term Paper=

Sickle Cell Anemia
Treatments exist for preventive and palliative treatment of sickle cell episodes, but no treatment has yet been developed to mitigate the effects of an attack once it has started. We need a way of dealing with Hbs fibers once they have polymerized. We feel we can develop a treatment for an ongoing attack by addressing the biomechanical basis of the pathology.


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Processivity

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DNA Stretching

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 * 3) Wang2 pmid=9138579

Miscellaneous

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Phage-based Artificial ECM
Synthetic ECM References

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polymer formulations∗ Howard J Walls1,3, Robert F Berg2 and Eric J Amis1
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Seung Min Hana, Corresponding Author Contact Information, E-mail The Corresponding Author, R. Shaha, R. Banerjeeb, G.B. Viswanathanb, B.M. Clemensa and W.D. Nixa
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Michael D. Buschmann 1, Yehezkiel A. Gluzband 1, Dr. Alan J. Grodzinsky 1 *, James H. Kimura 2, Ernst B. Hunziker 3
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