Keasling: Synthetic Biology Class/References

Readings for 1/25/2006:

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. []

Synthetic biology: engineering Escherichia coli to see light. []

Reading for 2/1/2006:

Reconstruction of genetic circuits. []

Reading for 2/8/2006:

Programming cellular function. []

Metabolic engineering for drug discovery and development. []

Reading for 2/15/2006:

A synthetic multicellular system for programmed pattern formation. []

Directed evolution of a genetic circuit. []

Reading for 2/22/2006:

Programmable ligand-controlled riboregulators of eukaryotic gene expression. []

Engineered riboregulators enable post-transcriptional control of gene expression. []

Reading for 3/1/2006:

Computational design of a biologically active enzyme. []

Designed divergent evolution of enzyme function. []

Reading for 3/8/2006:

Lessons from natural molecules. [[Media:walsh.pdf]]

The secondary metabolites and biosynthetic gene clusters of marine cyanobacteria. Applications in biotechnology. [[Media:Gerwick_et_al_Chapter_in_Proksch_book.pdf]]

Reading for 3/15/2006:

Reprogramming control of an allosteric signaling swith through modular recombination. [[Media:1904.pdf]]

The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway. [[Media:822.pdf]]