Aging bacteria

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News
8.13.06 Aging bacteria section started on oww

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Ideas

 * Aging iGEM project - coming soon


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Labs of interest

 * Martin Akkerman
 * Thomas Nystrom
 * Eric Stewart
 * Jonathan Visick
 * Tamara's lab


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Other resources

 * aging in E.Coli (Visick lab)

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Publications of interest

 * 1) Ackermann-science-2003 pmid=12817142
 * 2) Stewart-PLOSBiolgy-2005 pmid=15685293
 * 3) Nystrom-com-2002 pmid=12457704


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What is replicative senescence?
"Two fundamentally different aging phenomena have been described at the cellular level: 1) the gradual decline of life processes in postmitotic cells, and, 2) the decline and eventual complete cessation of cell division observed in most replicating cell lineages. The former is measured in simple chronological time, and comes into play during the aging of postmitotic adult organisms, such as the nematode, or during the aging of largely postmitotic tissues such as the brain or muscle in more complex organisms. In contrast, finite replicative lifespan, often referred to as 'cellular replicative senescence', is measured in terms of cell divisions rather than chronological time. The current consensus is that both postmitotic and replicative aging processes are causally related to the aging of humans." source: John Sedivy


 * Thanks to Knight lab for this template