User:Sean C. Sleight

Contact Info



 * Sean C. Sleight
 * University of Washington
 * Dept. of Bioengineering
 * Seattle, WA 98195
 * Email me through OpenWetWare

I'm a postdoc in Herbert Sauro's lab at University of Washington. I am working on a synthetic biology project and am an advisor for the UW iGEM team.

Education

 * 2007, PhD, Michigan State University, Microbiology and Molecular Genetics
 * 1999, BS, University of Arizona, Molecular and Cellular Biology

Research interests

 * 1) Synthetic biology
 * 2) Experimental and directed evolution
 * 3) Mutation rates under stress

Publications
Genetic basis of evolutionary adaptation by Escherichia coli to stressful cycles of freezing, thawing and growth. 2008. Genetics Sep;180(1):431-43.
 * Sleight S.C., C. Orlic, D. Schneider, and R.E. Lenski

Evolutionary adaptation to freeze-thaw-growth cycles in Escherichia coli. 2007. Physiological and Biochemical Zoology 80(4): 370-385.
 * Sleight S.C. and R.E. Lenski

Increased susceptibility to repeated freeze-thaw cycles in Escherichia coli following long-term evolution in a benign environment. 2006. BMC Evolutionary Biology 6: 104 [8 pp].
 * Sleight S.C., N.S. Wigginton, and R.E. Lenski

Useful links

 * In-Fusion BioBrick Assembly
 * Introductory tutorial
 * OpenWetWare help pages