Silver: Publications (1990-1999)

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1999

 * Morehouse, H., Buratowski, R.M., Silver, P.A., and Buratowski, S. The importin/karyopherin kap114 mediates the nuclear import  of TATA-binding protein. Proc. Natl. Acad. Sci. U.S.A.  1999; 96(22):12542-7.
 * Ferrigno, P. and Silver, P.A. Regulated nuclear localization of stress-responsive factors: how the nuclear trafficking of  protein kinases and transcription factors contributes to cell  survival. Oncogene 1999; 18(45):6129-34.
 * Moy, T.I. and Silver, P.A. Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins.  Genes & Dev. 1999; 13(16):2118-33.
 * Krebber, H., Taura, T., Lee, M.S., and Silver, P.A. Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block  in mRNA export. Genes & Dev. 1999;13(15):1994-2004.
 * Brodsky, A.S. and Silver, P.A. Nuclear transport HEATs up. Nat. Cell. Biol. 1999;1(3):E66-E67.
 * Zeng, X., Kahana, J.A., Silver, P.A., Morphew, M.K. McIntosh,J.R.,Fitch, I.T., Carbon, J., and Saunders, W.S. Slk19p is a centromere protein  that functions to stabilize mitotic spindles. J. Cell. Biol. 1999;146(2):415-25.
 * Defossez, P.A., Prusty, R., Kaeberlein, M., Lin, S.J., Ferrigno, P., Silver, P.A., Keil, R.L., and Guarente, L. Elimination of  replication block protein Fob1 extends the life span of yeast  mother cells. Mol. Cell 1999; 3(4):447-55.
 * Hood, J.K. and Silver, P.A. In or out? Regulating nuclear transport. Curr. Opin. Cell. Biol. 1999;11(2):241-7.
 * Valentini, S.R., Weiss, V.H., and Silver, P.A. Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3'-end  formation. RNA</B> 1999; 5(2):272-80.
 * Ferrigno, P. and Silver, P.A. Analysis of nuclear transport in vivo. Meth. Cell Biol.</B> 1999;58:107-22.
 * Seedorf, M., Damelin, M., Kahana, J.A., Taura, T., and Silver, P.A. Interactions between a nuclear transporter and a subset  of nuclear pore complex proteins depend on Ran GTPase. Mol.  Cell. Biol.</B> 1999;19(2):1547-57.

1998

 * Hood, J.K. and Silver, P.A. Cse1p is required for export of Srp1p/importin-alpha from the nucleus in Saccharomyces cerevisiae.  J. Biol. Chem.</B> 1998; 273(52):35142-6.
 * Silberstein, S., Schlenstedt, G., Silver, P.A., and Gilmore, R. A role for the DnaJ homologue Scj1p in protein folding in  the yeast endoplasmic reticulum. J. Cell. Biol.</B> 1998;143(4):921-33.
 * Ferrigno, P., Posas, F., Koepp, D., Saito, H., and Silver, P.A. Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires  the importin beta homologs NMD5 and XPO1. EMBO J.</B> 1998;17(19):5606-14.
 * Finley et al., Unified nomenclature for subunits of the yeast proteasome regulatory particle. TIBS</B> 1998; 23:244-245.
 * Taura, T., Krebber, H. and Silver, P.A. A member of the Ran binding protein family, Yrb2p, is involved in NES dependent nuclear  protein export. Proc. Natl. Acad. Sci. USA</B> 1998; 95:7427-7432.
 * Shen, E.C., Henry, M.F., Weiss, V.H., Valentini, S., Silver, P.A., and Lee, M.S. Arginine methylation facilitates the nuclear  export of hnRNPs. Genes & Dev.</B> 1998; 12:679-691.
 * Webb, C.D., Graumann, P., Kahana, J.A., Teleman, A., Silver, P.A. and Losick, R. Use of time-lapse microscopy to visualize  rapid movement of the replication origin region of the chromosome  during the cell cycle in Bacillus subtilis. Mol. Microbiol. </B> 1998; 28:883-892.
 * Kahana, J.A., Schlenstedt, G., Geiser, J.R., Evanchuck, D.M., Hoyt, A. and Silver, P.A. The yeast dynactin complex is involved  in partitioning the mitotic spindle between mother and daughter  cells during anaphase B. Mol. Biol. Cell</B> 1998; 9:1741-1756.
 * Huyett, A., Kahana, J., Silver, P., Zeng, X., and Saunders, W.S. Microtubule density controlled by antagonistic kinesin motors.  J. Cell Sci.</B> 1998; 111:295-301.
 * Vodicka, M.A., Koepp, D.M., Silver, P.A. and Emerman, M. HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage  infection. Genes & Dev.</B> 1998; 12:175-185.
 * Kahana, J. and Silver, P.A. The uses of GFP in yeast. in GFP: Green Fluorescent Protein Strategies and Applications,</B> ed.  by M. Chalfie and S. Kain; John Wiley & Sons, Inc. 1998, in press.
 * Scott, H.S., Antonarakis, S.E., Lalioti, M.D., Rossier, C., Silver, P.A., and Henry, M.F. Identification and characterization  of two putative human arginine methyltransferases (HRMT1L1 and  HRMT1L2). Genomics</B> 1998; 15:330-340.
 * Koepp, D. and Silver, P.A. Nucleo-cytplasmic transport and cell proliferation. BBA Reviews in Cancer</B> 1998; 1377:39-47.

1997

 * Taura, T., Schlenstedt, G. and Silver, P.A. Yrb2 is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue. <B>J.  Biol. Chem.</B> 1997; 272:31877.
 * Kessler, Henry, M., Shen, E., Zhao, J., Gross, S., Silver, P., and Moore, C.L. Hrp1, an RNA binding protein that shuttles  between the nucleus and cytoplasm, is required for mRNA 3' end  formation in yeast. <B>Genes & Dev.</B> 1997; 11:2545-2556.
 * Lithgow, T., Cuezva, J.M., and Silver, P.A. Highways for delivery to the mitochondria. <B>Trends in Biochemical Sciences</B> 1997;  110-113.
 * Corbett, A.H., Koepp, D.M., and Silver, P.A. Indirect immunofluorescence in Saccharomyces cerevisiae. in <B>Cell Biology: a Laboratory  Manual</B> ed. by David Spector; Cold Spring Harbor Press, 1997.
 * Silver, P.A. Scj1p. in <B>Guidebook to Molecular Chaperones and Protein Folding Catalysts,</B> ed. by M.-J. Gething; Sambrook  & Tooze at Oxford University Press, 1997.
 * Corbett, A. and Silver, P. Genetic analysis of nuclear transport. <B>Microbiology and Molecular Biology Reviews</B> 1997; 61:193-211.
 * Lee, M. and Silver, P.A. RNA movement from the nucleus. <B>Current Opinion in Genetics & Development</B> 1997; 212-219.
 * Seedorf, M. and Silver, P. A. Importin/Karyopherin protein family members required for mRNA export from the nucleus. <B>Proc.  Natl. Acad. Sci. USA</B> 1997; 94:8590-8595.
 * Clarkson, W.D., Corbett, A.H., Paschal, B.M., Kent, H.K., McCoy, A.J., Gerace, l., Silver, P.A., Stewart, M. Nuclear protein  import is descreased by engineered mutants of nuclear transport  factor 2 (NTF2) that do not bind GDP-Ran. <B>J. Mol. Biol.</B> 1997;  272:716-730.
 * Campbell, K.S., Mullane, K., Aksoy, I., Pipas, J.M., Silver, P.A., Roberts, T.M., Schaffhausen, B.S., and DeCaprio, J.A. The  J-domain of SV40 large TAg mediates Hsc70 binding and viral DNA  replication. <B>Genes & Dev.</B> 1997; 11:1098-1110.
 * Wong, D.H., Corbett, A.H., Kent, H., Stewart, M. and Silver, P.A. Interaction between the small GTPase Ran/Gsp1 and Ntf2 is  required for nuclear import. <B>Mol. Cell Biol.</B> 1997; 17:3755-3767.

1996

 * Kahana, J. and Silver, P. Use of the A. victoria green fluorescent protein to study protein dynamics in vivo. <B>Current Protocols  in Molecular Biology</B> 1996; 9.7.22-9.7.28.
 * Koepp, D. and Silver, P. A GTPase that controls nuclear trafficking: Running the right way or walking RANdomly? <B>Cell</B> 1996;  87:1-20.
 * Corbett, A., Ferrigno, P., Henry, M., Kahana, J., Koepp, D., Lee, M., Nguyen, L., Schlenstedt, G., Seedorf, M., Shen, E.,  Taura, T. and Silver, P. Genetic analysis of macromolecular transport  across the nuclear envelope. (Proceedings from the Nobel Symposium)  <B>Exp. Cell Res.</B> 1996; 229:212-216.
 * Koepp, D.M., Wong, D.H., Corbett, A.H., and Silver, P.A. Dynamic localization of the nuclear import receptor and its interactions  with transport factors. <B>J. Cell Biol.</B> 1996; 6:1163-1176.
 * DeHoratius, C. and Silver, P.A. Nuclear transport defects and nuclear envelope alterations are associated with mutation  of the Saccharomyces cerevisiae NPL4 gene. <B>Mol. Biol. Cell </B> 1996; 7:1835-1855.
 * Henry, M. and Silver, P. A novel arginine methyltransferase (HMT1) modifies a poly(A) RNA-binding protein. <B>Mol. Cell.  Biol.</B> 1996; 16:3668-3678.
 * Haarer, K., Corbett, A.H., Kweon, Y., Petzold, A.S., Silver, P.A. and Brown, S.S. SEC3 mutations are synthetically lethal  with profilin mutations and cause defects in diploid-specific  bud-site selection. <B>Genetics</B> 1996; 144:495-510.
 * Corbett, A.H. and Silver, P. A. The NTF2 gene encodes an essential highly conserved protein that functions in nuclear transport  in vivo. <B>J. Biol. Chem.</B> 1996; 271:18477-18484.
 * Lee, M., Henry, M., and Silver, P. A protein that shuttles between the nucleus and the cytoplasm is an important mediator  of RNA export. <B>Genes & Dev.</B> 1996; 10:1233-1246.
 * Henry, M., Borland, C., Bossie, M. and Silver, P. Potential RNA binding proteins in Saccharomyces cerevisiae identified as  suppressors of temperature-sensitive mutations in NPL3. <B>Genetics </B> 1996; 142:103-115.

1995

 * Koepp, D.M. and Silver, P. Rna1p, a GTPase activating protein, plays a direct role in nuclear transport. <B>J. NIH Research </B> 1995; 7:53-54.
 * Schlenstedt, G., Wong, D., Koepp, D. and Silver, P. Mutants in a yeast Ran binding protein are defective in nuclear transport.  <B>EMBO J.</B> 1995; 21:5367-5378.
 * Corbett, A., Koepp, D., Schlenstedt, G., Lee, M., Hopper, A., and Silver, P. Rna1p, a Ran/TC4 GTP-activating protein, is  required for nuclear import. <B>J. Cell Biol.</B> 1995; 130:1-10.
 * Kahana, J., Schnapp, B. and Silver, P. Kinetics of spindle pole body separation in budding yeast. <B>Proc. Natl. Acad. Sci.  USA</B> 1995; 92:9707-9711.
 * Loeb, J.D.J., Schlenstedt, G., Pellman, D., Kornitzer, D., Silver, P.A. and Fink, G.R. A yeast nuclear import receptor homologue  required for mitosis. <B>Proc. Natl. Acad. Sci. USA</B> 1995;  92:7647-7651.
 * Schlenstedt, G., Harris, S., Risse, B., Lill, R. and Silver, P. A yeast DnaJ homologue, Scj1, can function in the endoplasmic  reticulum with BiP/Kar2p via a conserved domain that specifies  interaction with Hsp70s. <B>J. Cell Biol.</B> 1995; 129:979-988.
 * Schlenstedt, G., Saavedra, C., Loeb, J., Cole, C. and Silver, P. The GTP-bound form of the yeast Ran/TC4 homologue blocks bi-directional  transport across the nuclear envelope. <B>Proc. Natl. Acad. Sci.  USA</B> 1995; 92:225-229.

1994

 * Flach, J., Bossie, M., Vogel, J., Corbett, A., Jinks, T., Willins, D., and Silver, P.A. A yeast RNA binding protein shuttles  between the nucleus and the cytoplasm. <B>Mol. Cell Biol.</B> 1994;  14:8399-407.
 * Osborne, M. A., Schlenstedt, G. Jinks, T. and Silver, P. Nuf2, a spindle pole body associated protein required for nuclear division  in yeast. <B>J. Cell Biology</B> 1994; 125:853-66.

1993

 * Osborne, M. and Silver, P. Nucleocytoplasmic transport in the yeast Saccharomyces cerevisiae. <B>Annual Review of Biochemistry </B> 1993; 62:219-54.
 * Silver, P. and Way, J. Eukarytotic DnaJ homologues and the specificity of hsp70 action. <B>Cell</B> 1993; 74:1-3.
 * Schlenstedt, G., Hurt, E., Doye, V. and Silver, P. Reconstitution of nuclear protein transport with semi-intact yeast cells. <B>J.  Cell Biology</B> 1993; 123:785-98.
 * Kurihara, T. and Silver, P. Suppression of a sec63 mutation identifies a novel component of the ER translocation apparatus.  <B>Mol. Biol. Cell</B> 1993; 4:919-30.
 * Nelson, M., Kurihara, T. and Silver, P. Extragenic suppressors of mutations in the cytoplasmic C-terminus of Sec63 define five  genes in S. cerevisiae. <B>Genetics</B> 1993; 134:159-73.
 * Stochaj, U., Bossie, M., van Zee, K. and Silver, P. Analysis of conserved binding proteins for nuclear localization sequences.  <B>J. Cell Science</B> 1993; 104:89-95.

1992

 * Kurihara, T. and Silver, P. DnaJ homologs and protein transport. in <B>Membrane Biogenesis and Protein Targeting,</B> ed. W. Neupert  and R. Lill; Elsevier Science Publishers, 1992; 309-27.
 * Bossie, M., Barcelo, G., Dehoratius, C., and Silver, P. A mutant nuclear protein with similarity to RNA binding proteins  interferes with nuclear import in yeast. <B>Mol. Biol. Cell</B> 1992;  3:875-93.
 * Stochaj, U. and Silver, P. A conserved phosphoprotein that specfically binds nuclear localization sequences is involved  in nuclear import. <B>J. Cell Biology</B> 1992; 117:473-82.

1991

 * Silver, P. How proteins enter the nucleus. <B>Cell</B> 1991; 64:489-97.
 * Blumberg, H. and Silver, P. A yeast protein containing two separated zinc fingers is required for normal cell growth. <B>Gene </B> 1991; 107:101-10.
 * Stochaj, U., Osborne, M., Kurihara, T. and Silver, P. A yeast protein that binds nuclear localization sequences: Purification,  localization and antibody inhibition of binding activity. <B>J.  Cell Biology</B> 1991; 113:1243-54.
 * Blumberg, H. and Silver, P. SCJ1, a DNAJ homologue that alters protein sorting in yeast. <B>Nature</B> 1991; 349:627-30.