CAST:TolosaPublication

LEAH TOLOSA, Ph.D. Assistant Director Center for Advanced Sensor Technology University of Maryland Baltimore County 1000 Hilltop Circle, Baltimore, MD 21050 410-455-3432 (office), 410-455-6500 (fax) email: [mailto:leah@umbc.edu leah@umbc.edu] Back to Leah Tolosa CV

Journal Publications

 * 1) Bartolome, A., Smalls-Mantey, L., Lin, D., Rao, G., Tolosa, L. “FRET-based glucose monitoring for bioprocessing”, Genetically Engineered Probes for Biomedical Applications, Proc. of SPIE, 6098, 60980L-1 – 8, 2006.
 * 2) Kostov, Y., Smith, D. S., Tolosa, L., Rao, G., Gryczynski, I., Gryczynski, Z., Malicka, J., Lakowicz, J. R. (2005) Directional Surface Plasmon-Coupled Emission from a 3 nm Green Fluorescent Protein Monolayer, Biotech. Prog., 21, 1731-1735.
 * 3) Bartolome, A., Bardliving, C., Rao, G., Tolosa, L. (2005) Fatty acid sensor for low-cost lifetime-assisted ratiometric sensing using a fluorescent fatty acid binding protein, Anal. Biochem., 345, 133-139.
 * Ge, X., Tolosa, L. (corresponding author), Rao, G. (2004) Dual-labeled glucose binding protein for ratiometric measurements of glucose, Anal. Chem., 76, 1403-1410.
 * Ge, X., Tolosa, L., Simpson, J., Rao, G. (2003) Genetically engineered binding proteins as biosensors for fermentation and cell culture, Biotech. Bioeng., 84, 723-731.
 * 1) Tolosa, L., Ge, X., Kostov, Y., Lakowicz, J. R., Rao, G. (2003) Dual-emitting biosensors for glucose and glutamine from genetically engineered E. coli binding proteins, Proc. SPIE Genetically Engineered and Optical Probes for Biomedical Applications, 4967, 19-25.
 * 2) Kostov, Y., Tolosa, L., O’Connell, K., Anderson, P., Liu, Y., van Beek, N., Rao, G. (2003), Monitoring DsRed protein concentration in frozen insect larvae, Proc. SPIE Genetically Engineered and Optical Probes for Biomedical Applications, 4967, 100-107.
 * 3) Tolosa, L., Ge, X., Rao, G., (2003) Reagentless optical sensing of glutamine using a dual-emitting glutamine-binding protein, Anal. Biochem., 314, 199-205.
 * 4) Tolosa, L., Kostov, Y., Harms, P., Rao, G. (2002) Non-invasive measurement of dissolved oxygen in shake flasks, Biotech. Bioeng., 80, 594-597.
 * 5) Murtaza, Z., Tolosa, L., Harms, P. and Lakowicz, J. R. (2002) On the Possibility of Glucose Sensing Using Boronic Acid and Luminescent Ruthenium Metal-Ligand Complex, J. Fluorescence, 12(2), 187-192.
 * 6) Lakowicz, J.R., Gryczynski, I., Piszczek, G., Tolosa, L., Nair, R., Johnson, M.L., Nowaczyk, K. (2000) Microsecond dynamics of biological macromolecules, Methods in Enzymology, 23, 473-509.
 * 7) Kumar, C. V., Tolosa, L. M., (1999) Exploring the hydrophobic binding sites of calmodulin with fluorescent probes: Dynamic formation of the excimer, Indian Journal of Chemistry, 38B, 1170-1183.
 * 8) Lakowicz, J. R., Gryczynski, I., Gryczynski, Z., Tolosa, L., Dattelbaum, J. D., Castellano, F. N., Abugo, O. (1999) Emerging Fluorescence Technologies in Clinical Chemistry, Clinical Chemistry, Proceedings of the Oak Ridge Conference on the Road to Non-Invasive Testing.
 * 9) Lakowicz, J. R., Gryczynski, I., Dattelbaum, J.D., Tolosa, L., Rao, G. (1999) Novel Methods of Fluorescence Sensing, SPIE Conference on Advances in Fluorescence Sensing Technology IV, 3602, 234-240.
 * 10) Tolosa, L., Gryczynski, I. Randers-Eichhorn, L., Dattelbaum, J.D., Rao, G. and Lakowicz, J. R. (1999) Glucose Sensing, SPIE Conference on Advances in Fluorescence Sensing Technology IV, 3602, 46-51.
 * 11) Lakowicz, JR, Gryczynski I., Gryczynski Z., Tolosa, L. Dattelbaum, J. D.,and Rao, G. (1999) Polarization-Based Sensing with a Self-Referenced Sample, Applied Spectroscopy, 53(9), 1149-1157.
 * 12) Lakowicz, JR, Gryczynski I., Gryczynski Z., Tolosa, L. Randers-Eichorn, L.,and Rao, G. (1999) Polarization- Based Sensing of Glucose Using an Oriented Reference Film, Journal of Biomedical Optics, 4(4), 443-449.
 * 13) Tolosa, L., Gryczynski, I., Eichorn, L., Dattelbaum, J., Castellano, F. N., Rao, G. and Lakowicz, J. R.,(1999) Glucose Sensor for Low Cost Lifetime-Based Sensing Using a Genetically Engineered Protein, Anal. Biochem., 267(1), 114-120.
 * 14) Lakowicz, JR, Gryczynski, I., Tolosa, L., Dattelbaum, J. D., Castellano, F. N., Li, L. and Rao, G. (1999) Advances in Fluorescence Spectroscopy: Multi-Photon Excitation, Engineered Proteins, Modulation Sensing and Microsecond Rhenium Metal-Ligand Complexes, Proceedings of the Jablonski Conference, Acta Physica Polonica 99(1), 179-196.
 * 15) Lakowicz, JR, Castellano, F. N., Dattelbaum, J. D., Tolosa, L.,Rao, G.and Gryczynski, I (1998) Low Frequency Modulation Sensors Using Nanosecond Fluorophores, Anal. Chem., 70, 5115-5121.
 * 16) Tolosa, L. M., Malak, H., Rao, G. and Lakowicz, J. R., (1997) Optical Assay for Glucose Based on the Luminescence Decay Time of the Long Wavelength Dye Cy5TM, Sensors and Actuators B, 45, 93-99.
 * 17) Tolosa, L. M., Szmacinski, H., Rao, G. and Lakowicz, J. R. (1997) Lifetime-based Sensing of Glucose Using Energy Transfer with a Long Lifetime Donor, Analytical Biochemistry, 250, 102-108.
 * 18) Kumar, C. V. and Tolosa, L. M. (1994) 2,6-Bis(pyren-1-oyl)pyridine: A new Fluorescent Probe with a High Sensitivity to Hydrogen Bonding Solvents for the Development of Selective Sensors, J. Photochem. And Photobiol. A: Chem. Sec., 78, 63-69.
 * 19) Kumar, C. V. and Tolosa, L. M. (1993) Interaction of Hydrophobic Probes with Serum Albumin - Influence of the Side Chain and Exciplex Formation at the Binding Site, J. Phys. Chem., 97, 13914-13919.
 * 20) Tolosa, L. M. and Kumar, C. V. (1993) The Role of the Side Chain, Charge, and Hydrophobicity on the Protein Binding Affinity of Simple Fluorescent Molecules, FASEB J., 7(7), A1131.
 * 21) Kumar, C. V. and Tolosa, L. M. (1993) New Charge Transfer Probe for Solvent Polarity: Fluorescent Hydrogen Bonding Switch, Chem. Comm., 722.
 * 22) Radia, S. M., Kumar, C. V. and Tolosa, L. M. (1992) A New Approach for the Design of Sequence Specific Fluorescent Probes for DNA, Proceedings - National Conference for Undergraduate Research VI, 1796-1800.
 * 23) Tolosa, L. M. and Sevilla, F. B. (1987) Copper and Zinc in Hair Samples from Filipinos with Pulmonary Tuberculosis, Acta Manilana, 36, 51-57.

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