Neomycin

Experimental

 * target organism: bacteria, mammalian cells
 * stock solution: 10mg/ml in water
 * working solution: 10-50µg/ml (stable at RT for 5days)

Description

 * mode of action: binds to ribosomal components and inhibits protein synthesis.
 * mode of resistance: neo/kan resistance gene is an aminoglycoside 3'-phosphotransferase, which inactivates G418, neomycin, and kanamycin by phosphorylation.

Links

 * related antibiotics: kanamycin, G418
 * list of cell culture reagents by Krackeler
 * list of cell culture reagents by USB
 * forum thread on difference between neomycin & G418