User:Deng-Ke Niu

Contact Info



 * Deng-Ke Niu
 * College of Life Sciences, Beijing Normal University
 * Xinjiekouwai Street 19
 * Beijing, China.
 * Email me through OpenWetWare

Education

 * 1999, PhD, Wuhan University
 * 1996, MS, Lanzhou University
 * 1993, BS, Hebei University


 * 2001-2003, Postdoc, Beijing Normal University
 * 2000-2001, CNRS-University Paul Sabatier, Toulouse III
 * 1999-2001, Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan

Research interests

 * 1) The origin and evolution of introns, including the possible costs and benefits of introns, the mechanisms of intron gain and intron loss


 * 1) Theoretical consideration on various problems. Propose hypotheses to remind other researchers the unnoticed possibilities.

Publications

 * Niu D-K, Cao J-L (2010) Nucleosome deposition and DNA methylation may participate in the recognition of premature termination codon in nonsense-mediated mRNA decay. FEBS Lett. 584:3509-3512
 * Li N, Lv J, Niu D-K (2009) Low contents of carbon and nitrogen in highly abundant proteins: Evidence of selection for the economy of atomic composition. J. Mol. Evol. 68:248-255
 * Huang Y-F, Niu D-K (2008) Evidence against the energetic cost hypothesis for the short introns in highly expressed genes. BMC Evol. Biol. 8:154
 * Niu DK (2008) Exon definition as a potential negative force against intron losses in evolution. Biol. Direct 3:46
 * Lv J, Li N, Niu D-K (2008) Association between the availability of environmental resources and the atomic composition of organismal proteomes: Evidence from Prochlorococcus strains living at different depths. Biochem. Biophys. Res. Commun. 375:241-246
 * Wang HF, Hou WR, Niu DK (2008) Strand compositional asymmetries in vertebrate large genes. Mol. Biol. Rep. 35:163-169
 * Niu D-K (2007) Protecting exons from deleterious R-loops: a potential advantage of having introns. Biol. Direct 2:11
 * Li S-W, Feng L, Niu D-K (2007) Selection for the miniaturization of highly expressed genes. Biochem. Biophys. Res. Commun. 360:586-592
 * Wang H-F, Feng L, Niu D-K (2007) Relationship between mRNA stability and intron presence. Biochem. Biophys. Res. Commun. 354:203-208
 * Feng L, Niu D-K (2007) Relationship between mRNA stability and length: An old question with a new twist. Biochem. Genet. 45:131-137
 * Hou W-R, Wang H-F, Niu D-K (2006) Replication-associated strand asymmetries in vertebrate genomes and implications for replicon size, DNA replication origin, and termination. Biochem. Biophys. Res. Commun. 344:1258-1262
 * Niu D-K (2005) Low-level illegitimate transcription of genes may be to silence the genes. Biochem. Biophys. Res. Commun. 337:413-414
 * Niu D-K, Hou W-R, Li S-W (2005) mRNA-mediated intron losses: evidence from extraordinarily large exons. Mol. Biol. Evol. 22:1475-1481
 * Niu DK, Lin K, Zhang D-Y (2003) Strand compositional asymmetries of nuclear DNA in eukaryotes. J. Mol. Evol. 57:325-334
 * Niu DK, Chen JK, Liu YD (2001) Margulis' theory on division of labour in cells revisited. Acta Biotheor. 49:23-28
 * Niu DK, Chen JK (1998) Origin of cancerous cells from tumours. Acta Biotheor. 46:379-381
 * Niu DK, Chen JK (1997) Evolutionary advantages of cell specialization: Save and protect DNA. J. Theor. Biol. 187:39-43
 * Niu DK, Wang MG, Wang YF (1997) Plant cellular osmotica. Acta Biotheor. 45:161-169
 * Niu DK, Wang YF (1995) Why animals have tumors. Acta Biotheor. 43:279-280
 * And several papers in Chinese with English abstracts.


 * for abstracts and links to fulltexts, please search Pubmed

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