Eccles:The Otago Medical School Research Society

The 184th Scientific Meeting of The Otago Medical School Research Society presents an invited lecture by

Professor Kurt Krause Department of Biochemistry, University of Otago

New protein crystallography capabilities at the University of Otago and a proposed CoRE in infectious diseases

Thursday 24th August @ 5 pm Barnett Lecture Theatre

To be followed by refreshments

Dr. Kurt Krause is a professor of Biochemistry at the University of Otago in Dunedin, New Zealand. He obtained his M.D. at Baylor College of Medicine in Houston, Texas in 1980. He received his M.A. and Ph.D. in Chemistry from Harvard University in 1983 and 1986, respectively. He carried out his doctoral research in the laboratory of Nobel Laureate William N. Lipscomb, Jr. His research areas include structural biology of infectious diseases, structure-aided drug design, protein crystallography, X-ray diffraction, structure and function of enzymes and proteins including antibiotic targets, redox proteins, nucleases, luciferase, and bacterial pathogenesis factors. Dr. Krause is board certified in Internal Medicine and is a specialist in infectious diseases. He has extensive experience in the treatment of HIV/AIDS and tuberculosis.

Dr. Krause has over 20 years of experience in protein crystallography including purification and crystallization of proteins, high resolution data collection, structure determination via MAD, MIR as well as molecular replacement methods, building and refinement, and structural interpretation. In his group there is a long-standing interest in the structure and function of drug targets, virulence factors and redox proteins, especially those from highly pathogenic organisms. Dr. Krause also has experience in MIC/MBC determinations in drug resistant bacteria and in mechanisms of antimicrobial resistance.