CHE.496/2008/Projects/2/Group 3

Patrick Gildea & Dan Tarjan project overview and part design

 * Project Ideas
 * Double Repressilator with different transcriptional rates regulated by a toggle switch
 * Metabolic engineering of E.Coli or Yeast to manufacture spider silk (gossamar) fiber
 * Neurotransmitters as messengers between non-neuron cells
 * Negative feed-back switch
 * Catenin/Cadherin
 * Cancer inhibitor that replaces invasin as a mode of attacking cancerous cells via inhibiting critical pathways in cancerous tumors that results in apoptosis of the tumor
 * Synthetic Organelle: Make a membrane bound region in which a controlled environment can exist. Would need to be able to control membrane proteins present.
 * Photosynthesis:
 * Manufacture of Antibodies in E. Coli or Yeast
 * Orphan Drugs - to be listed...
 * Zevalin: monoclonal antibody
 * Lopinavir: protease inhibitor?
 * Cerezyme: imiglucerase?


 * 2 Projects in Detail:
 * DuoRepressilator
 * Cadherin cell adhesion hooks