Biomod/2011/LMU/FolD'N'Assemble/Project

The Project
For our project we decided on designing a DNA based drug delivery vehicle.

DNA, as a building material, is very easy and safe to work with. So the idea to use it as a delivery vehicle came up naturally. When molecules are transported into a cell (endocytosis), they are absorbed by endosomes. The endosomes lower their pH value to 4-5. We want to use that process of pH change to open our container and release its payload.