Larry Lok

I am a scientist at the Molecular Sciences Institute in Berkeley, CA. You can find more about me on this page.

I have taken a look at several papers connected with ODE parameter estimation, and written up some [[Media:LokParamEstNotes.pdf | notes]] about them. Here are the papers themselves, including those that Koichi distributed:
 * [[Media:Kikuchi2003.pdf | Kikuchi et al. 2003]]
 * [[Media:MolesMendesBanga.pdf | Moles, Mendes, and Banga, 2003]]
 * [[Media:ObiYagns.pdf | Kimura et al. 2004]]
 * [[Media:RunarssonYao.pdf | Runarsson and Yao 2000]]
 * [[Media:Sugimoto2005.pdf | Sugimoto et al. 2005]]

Here is an old [[Media:Optimization_scheme.pdf | write-up]] of a program to find time-varying input that maximizes the sensitivity of the response to a particular model parameter (a reaction rate as we discussed it previously.) This is the same genetic algorithm-type thing that Ty suggested long ago and which we have been talking about since Ty's simulation results that located such an input function.