Reactome & cMAP

This presentation from the BioMIBLab Summer 2006 Workshop is an imaging bioinformatics tool.

This presentation includes a comparison of the features of two bioinformatics tools, Reactome and cMAP.


 * [[Image:Reactome.png|60px]][[Image:CMAP.png]]

Synopsis

 * Reactome
 * Curated resource of core pathways and reactions in human biology and 21 non-human species.


 * cMAP
 * A prototype system to access and link molecular profiles, molecular targets, targeted agents, and clinical data.

Features

 * Reactome
 * Data model / Schema
 * consists of pathways, reactions, entities


 * Search / Extended search
 * links to external references


 * Pathfinder
 * finds pathways linked with input/output compounds


 * Skypainter
 * identifies significant events linked with genes


 * Downloads
 * manage local versions


 * Editorial calendar
 * lists planned updates, curation information


 * cMAP
 * Context
 * defines tissue and histology types


 * Molecular profiles
 * displays expression ratios spatially in chromosomal and 2D array formats


 * Molecular targets
 * organizes gene targets based on:
 * ontology (GO)
 * pathways (BioCARTA)
 * CMAP annotated pathways


 * Targeted agents
 * found in CTEP, CMAP trials


 * Clinical trials

Full Presentation
[[Media:Reactome.ppt|Reactome & cMAP PowerPoint Presentation]]

Links
cMAP Homepage

Reactome Homepage