IGEM:Stanford/Immunosuppression DeviceChallenges

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Pathogenicity
Goal: To identify the factors that lead E. coli to provoke an immune response from Th17 cells and design methods to preclude such pathogenicity.
 * g. Working off of Bactoblood: correspond with Berkeley’s Team and study their project to understand how they modified E. coli to reduce its pathogenicity. To what extent should our procedures mirror theirs? Can we optimize their design?
 * h. In Context of Th17: What are the specific interactions between E. coli and Th17 cells? How can we modify our machine to preclude unwanted stimulation and activation of the Th17 lineage?