WangLab:Integrin Antibodies

Integrin Antibodies

 * Wow-1, binds to high affinity unoccupied integrins avb3, detecting affinity increase
 * LIBS-6,binds to occupied b3 and stablize it, therefore activate it, with high concentration 15ug/ml
 * HUTS-21, binds to occupied u1 and stablize it, activate
 * EDTA, specifically block binding to avb3.
 * 16G3, block unoccupied FN sites (avb3, a5b1)
 * 3B8, block unoccupied FN sites (a5b1)
 * 11E5, non-blocking control for 16G3, 3B8
 * 661, blocking binding sites on Vitronectin for avb3
 * 443, non-blocking control for 661.
 * MnCl2, activates all the integrins (0.5mM).