Drummond:Publications

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Research

 * 1) Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast. Geiler-Samerotte KA, Dion MF, Budnik BA, Wang SM, Hartl DL, Drummond DA.  Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):680–685.  Epub  2010 Dec 27. PDF, PDF+HTML, Supplementary data.
 * 2) Mistranslation-induced protein misfolding as a dominant constraint on coding-sequence evolution. Drummond DA, Wilke CO. Cell. 2008 Jul 25;134(2):341-52. Faculty of 1000 rated Preview by Powers and Balch. Full text, supplementary materials, data.
 * 3) Contact density affects protein evolutionary rate from bacteria to animals. Zhou T, Drummond DA, Wilke CO.  J Mol Evol. 2008 Apr;66(4):395-404. Epub 2008 Apr 1.
 * 4) A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments. Li Y, Drummond DA, Sawayama AM, Snow CD, Bloom JD, Arnold FH. Nat Biotechnol. 2007 Sep;25(9):1051-6. Epub 2007 Aug 26. Erratum in: Nat Biotechnol. 2007 Dec;25(12):1488. Faculty of 1000 rated
 * 5) Structural determinants of the rate of protein evolution in yeast. Bloom JD, Drummond DA, Arnold FH, Wilke CO. Mol Biol Evol. 2006 Sep;23(9):1751-61. Epub 2006 Jun 16.
 * 6) Population genetics of translational robustness. Wilke CO, Drummond DA. Genetics. 2006 May;173(1):473-81. Epub 2006 Feb 19.
 * 7) A single determinant dominates the rate of yeast protein evolution. Drummond DA, Raval A, Wilke CO. Mol Biol Evol. 2006 Feb;23(2):327-37. Epub 2005 Oct 19. Faculty of 1000 rated
 * 8) Why highly expressed proteins evolve slowly. Drummond DA, Bloom JD, Adami C, Wilke CO, Arnold FH. Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14338-43. Epub 2005 Sep 21. Faculty of 1000 rated
 * 9) Predicting the tolerance of proteins to random amino acid substitution. Wilke CO, Bloom JD, Drummond DA, Raval A. Biophys J. 2005 Dec;89(6):3714-20. Epub 2005 Sep 8.
 * 10) Why high-error-rate random mutagenesis libraries are enriched in functional and improved proteins. Drummond DA, Iverson BL, Georgiou G, Arnold FH. J Mol Biol. 2005 Jul 22;350(4):806-16. Faculty of 1000 rated
 * 11) On the conservative nature of intragenic recombination. Drummond DA, Silberg JJ, Meyer MM, Wilke CO, Arnold FH. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5380-5. Epub 2005 Apr 4.
 * 12) Thermodynamic prediction of protein neutrality. Bloom JD, Silberg JJ, Wilke CO, Drummond DA, Adami C, Arnold FH. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):606-11. Epub 2005 Jan 11. Faculty of 1000 rated

Reviews

 * 1) Signatures of protein biophysics in coding sequence evolution. Wilke CO, Drummond DA. Curr Opin Struct Biol. 2010 Jun;20(3):385-9. Epub 2010 Apr 13. Review.
 * 2) Protein evolution: innovative chaps. Drummond DA. Curr Biol. 2009 Sep 15;19(17):R740-2.
 * 3) The evolutionary consequences of erroneous protein synthesis. Drummond DA, Wilke CO. Nat Rev Genet. 2009 Oct;10(10):715-24. Review.