Kaipparettu Lab :Publications

(Publications before 2006 are with the name Abraham BK instead of Kaipparettu BA due to official name change in my passport in 2006) 

 Books


 * Abraham BK, Adithan C. Endocrine Pharmacology. In. Adithan C. Status report of Indian Pharmacological research 1994-1998, published by Indian National Science Academy, 2000, pp 68-80

Reviews


 * Abraham BK & Adithan C. Genetic polymorphism of CYP2D6. Ind J Pharmacol 2001; 33:147-69


 * Kaipparettu BA, Ma Y, Wong LJ. Functional effects of cancer mitochondria on energy metabolism and tumorigenesis: utility of transmitochondrial cybrids. Ann NY Acad Sci  2010;1201(1):137-46.


 * Vithayathil SA, Ma Y, Kaipparettu BA*. Tools to study the functional consequence of mtDNA mutations: Cybrids (in press). (*Corresponding Author)

Research Articles


 * 1)      Abraham BK, Adithan C, Shashindran CH, Vasu S, Alekutty NA. Genetic polymorphism of CYP2D6 in Keralite (South India) population. Br J Clin Pharmac 49:285-6, 2000
 * 2)      Abraham BK, Adithan C, Kiran UP, Asad M, Koumaravelou K. Genetic Polymorphism of CYP2D6 in Karnataka and Andhra Pradesh population. Acta Pharmacol Sin 21:494-8, 2000  4
 * 3)      Abraham BK, Adithan C, Mohanasundaram J, Shashindran CH, Koumaravelou K, Asad M. Genetic polymorphism of CYP2D6 in Tamil population. Eur J Clin Pharmacol 56:849-50, 2001
 * 4) 	Asad M, Shewade DG, Abraham BK, Koumaravelou K, Balasinor N, Ramaswamy S. Effect of hyperprolactinemia as induced by pituitary homografts under kindney capsule on gastric and duodenal ulcers. J Pharm Pharmacol 58:1541-7, 2001
 * 5) 	Asad M, Shewade DG, Koumaravelou K, Abraham BK, Vasu S, Ramaswamy S. Effect of centrally administered prolactin on gastric and duodenal ulcers in rats. Fund Clin Pharmacol 3:175-9, 2001
 * 6) 	Asad M, Shewade DG, Abraham BK, Koumaravelou K, Vasu S,Ramaswamy S. Effect of centrally administered oxytocin on gastric and duodenal ulcers in rats. Acta Pharmacol Sin 22(6):488-92, 2001
 * 7) 	Asad M, Shewade DG, Koumaravelou K, Abraham BK, Vasu S, Ramaswamy S. Gastric anti-secretory and anti-ulcer activity of oxytocin in rats and Guinea pigs. Life Sciences 70:17-24, 2001
 * 8) 	Koumaravelou K, Adithan C, Shashindran CH, Asad M, Abraham BK. Influence of honey on orally and intravenously administered diltiazem kinetics in rabbits. Indian J Exp Biol 40:1164-8, 2002
 * 9) 	Koumaravelou K, Adithan C, Shashindran CH, Asad M, Abraham BK. Effect of honey on carbamazepine kinetics in rabbits. Indian J Exp Biol 40:560-3, 2002
 * 10) 	Naveen AT, Adithan C, Padmaja N, Shashindran CH, Abraham BK, Satyanarayanamoorthy K, Anitha P, Gerard N, Krishnamoorthy R. Glutathione S-transferase M1 and T1 null genotype distribution in South Indians. Eur J Clin Pharmacol 60:403-6, 2004
 * 11) 	Abraham BK, Justenhobrn C, Pesch B, Harth V, Hamann U, Bruening and Brauch H for GENICA net work. Investigation of genetic variants of genes of the Hemochromatosis pathway and their role in breast cancer. Cancer Epidemiol Biomarkers Prev 14:1102-7, 2005
 * 12) 	Abraham BK, Fritz P, McClellann M, Hauptvogel P, Brauch H. Prevalence of CD44+/CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis. Clin Cancer Res 11:1154-9, 2005 (The fist follow-up publications on the clinical significance of putative breast cancer stem cells in primary breast tumors after its initial characterization. Currently this paper has cited by more than 150 publications)
 * 13) 	Jose R, Chandrasekaran A, Sam SS, Gerard N, Chanolean S, Abraham BK, Satyanarayanamoorthy K, Peter A, Rajagopal K. CYP2C9 and CYP2C19 genetic polymorphisms: Frequencies in the South Indian population. Fundam Clin Pharmacol 19:101-5, 2005
 * 14) 	Jaremko M, Justenhoven C, Abraham BK, Schroth W, Fritz P, Brod S, Vollmert C, Illig T, Brauch H. MALDI-TOF and TaqMan assisted SNP genotyping of DNA isolated from formalin-fixed and paraffin-embedded tissues (FFPET). Hum Mut 25:232-8, 2005
 * 15) 	Jaremko M, Justenhoven C, Schroth W, Abraham BK, Fritz, P, Vollmert C, Illig T, Simon W, Schwab M, Brauch H. Polymorphism of the DNA repair enzyme XRCC1 is associated with treatment prediction in anthracycline and cyclophosphamide/methotrexate/5-fluorouracil-based chemotherapy of patients with primary invasive breast cancer. Pharmacogen Genom 17(7):529-38, 2007
 * 16) 	Kaipparettu BA*, Malik S, Konduri SD, Liu W, Rokavec M, van der Kuip H, Hoppe R, Hammerich-Hille S, Fritz P, Schroth W, Abele I, Das GM, Oesterreich S, Brauch H. Estrogen-mediated downregulation of CD24 in breast cancer cells. Int J Cancer 123 (1):66-72, 2008 (*Corresponding Author)
 * 17) 	Kaipparettu BA, Kuiatse I, Tak-Yee Chan B, Benny Kaipparettu M, Lee AV, Oesterreich S. Novel egg white-based 3-D cell culture system. Biotechniques. 45(2):165-8, 2008 (cover page, cover image article and breaking news).
 * 18) 	Kaipparettu BA*, Dobrzycka KM, Britton O, Lee AV, Herron AJ, Li Y, Lewis MT, Medina M, Oesterreich S. Scaffold attachment factor B1 (SAFB1) heterozygosity does not influence Wnt-1 or DMBA-induced tumorigenesis. Molecular Cancer 6;8:15.2009 (*Corresponding Author)
 * 19) 	Hammerich-Hille S*, Kaipparettu BA*, Tsimelzon A, Creighton CJ, Jiang S, Polo JM, Melnick A, Meyer R, Oesterreich S (2009) SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells J Biol Chem 285(6):3608-16, 2010. (*Shared first authors)
 * 20) 	Konduria SD, Medisettya R, Liua W, Kaipparettu BA, Srivastava P, Brauch H, Fritz P, Swetziga WM, Gardnerf AE, Khanf SA, and Das GM. Mechanisms of estrogen receptor antagonism toward p53: Implications in breast cancer therapeutic response and stem cell regulation. PNAS 24;107:15081-6, 2010
 * 21) 	Tu YF, Kaipparettu BA, Ma Y, Wong LJ. Mitochondria of highly metastatic breast cancer cell line MDA-MB-231 exhibits increased autophagic properties Biochim Biophys Acta (in press).

Manuscript under submission/revision:


 * 1) 	Ma Y, Kaipparettu BA, Trieu R, Wong LJ. Mitochondria from non-cancerous cells can reverse the oncogenic properties of a cancer cell: Evidence from Transmitochondrial Cybrid Studies
 * 2) 	Ma Y, Kaipparettu BA, Bai RK, Wong LJ. Mitochondria from metastatic breast cancer cell line MDA-MB-231 cells induce oncogenic properties in non-cancerous breast epithelial cells

ABSTRACTS 


 * Kaipparettu BA, Sanchez LY, Xu X, Dawson BC, Napierala D, Jiang S, Dearth R, Pathiraja T, Dickson G, Thompson A, Hammerich-Hille S, Lappin T, Lee B, Cooney A, Oesterreich S. Expression of genes in the homeobox cluster is epigenetically altered with the loss of scaffold attachment factor-B1 (SAFB1). Cancer Epigenome Workshop, May 2009, Houston, TX.


 * Pathiraja TN, Xi Y, Lee AV, Senten R, Gannon F, Kaipparettu BA, Chang J, Oesterreich S. Estrogen deprivation results in altered DNA methylation profile in breast cancer cells-Role in endocrine resistance? Center Cancer Epigenome Workshop, May 2009, Houston, TX.


 * Kaipparettu BA, Wang J, Jiang S, Garee J, Huang J, Oesterreich S. Scaffold attachment factor-B1 (SAFB1) is a critical regulator of immune system. AACR Annual conference April, 2009 Denver, CO (Later Breaking Abstract).


 * Kaipparettu BA, Sanchez LY, Jiang S, Pathiraja T, Thompson A, Hammerich-Hille S, Lappiin T, Oesterreich S.  Scaffold attachment factor-B1 epigenetically regulates homeobox gene expression in mouse embryonic fibroblasts. Keystone symposia ‘Chromatin Dynamics and Higher Order Organization’  February, 2009 Coeur d'Alene Resort, Coeur d'Alene, ID.


 * Kaipparettu BA, Kuiatse I, Tak-Yee Chan B, Benny Kaipparettu M, Lee AV, Oesterreich S. Novel egg white-based 3-D cell culture system. San Antonio Breast Cancer Symposium, December, 2008 San Antonio, TX.


 * Das GM, Konduri SD, Liu W, Sayeed A, Bansal S, Abraham BK, Brauch H, Fritz P. Inactivation of tumor suppressor p53 by estrogen receptor: Mechanisms of a novel phenomenon with translational implications. AACR Annual Meeting- Apr, 2008; San Diego, CA.


 * Kaipparettu BA, Hille S, Tsimelzon A, et al. The Corepressor SAFB in Breast Cancer - Identification of Target Genes. 30th Annual San Antonio Breast Cancer Symposium. December, 2007, San Antonio, TX.


 * Kaipparettu BA, Jiang S, Thompson A, Lappin T, Oesterreich S. Scaffold attachment factor-1 (SAFB1) regulates HOX gene expression in immortalized mouse embryonic fibroblast. FASEB Summer research conference on “Nuclear Structure and Cancer”, June, 2007, Vermont Academy, Saxtons River, VT.


 * Kaipparettu BA, Jiang S, Kohwi-Shigematsu T, Oesterreich S. The Transcriptional Repressor SAFB1 binds to S/MARs via an N-terminal SAF-Box. ASBMB conference on Transcriptional Regulation by Chromatin and RNA Polymerase II, November 2006, Kiawah Island, SC.


 * Abraham BK, Das G, Liu W, et al. CD24 expression is regulated by ERα and the CD24 gene is silenced by hypermethylation in invasive breast cancers. AACR special conference, September, 2005, La Jolla, CA.


 * Abraham BK, Das G, Liu W, Rokavec et al. Interaction of CD24 and ERα in breast cancer. GBM Annual Fall meeting September, 2005, Berlin, Germany.


 * Abraham BK, Fritz P, Van der Kuip H, et al Evaluation of CD44+/CD24-/low cells in breast cancer and relevance for distant metastasis. AACR Annual Meeting, April, 2005, Anaheim, CA.


 * Jaremko M, Justenhoven C, Fritz P, Abraham BK, et al. Identification of treatment predictive markers for breast cancer patients with chemotherapy. AACR Annual Meeting, April, 2005, Anaheim, CA.


 * Abraham BK, Justenhobrn C, Pesch B, et al. Breast cancer risk and genetic variants of hereditary hemochromatosis: Individual mutations of HFE, FPN1, TfR1 and TfR2 are not direct risk factors. Breakthrough 'Biology of Breast Cancer' Conference, March, 2004, Brighton, United Kingdom.


 * Abraham BK, Fritz P, McClellann M, Hauptvogel P, Brauch H. Double staining for the detection of CD44+/CD24-/low in clinical samples cannot identify tumorigenic breast cancer cells. AACR Annual meeting, March, 2004, Orlando, FL.


 * Abraham BK, Adithan C, Shashindran CH, Vasu S, Alekutty NA. Genetic polymorphism of CYP2D6 in Keralite (South India) population. Southern regional conference of Indian Pharmacological Society, 1999, Perundurai, India.


 * Abraham BK, Adithan C, Kiran UP, Asad M, Koumaravelou K. Genetic polymorphism of CYP2D6 in Karnataka and Andhra Pradesh  population. International congress on Frontiers in Pharmacology and Therapeutics in 21st Century,1999, Delhi, India.


 * Abraham BK, Adithan C, Mohanasundaram J, Shashindran CH, Koumaravelou K, Asad M. Genetic polymorphism of CYP2D6 in Tamil population. Southern regional conference of Indian Pharmacological Society, 2000, Bangalore, India.