Imperial College/Courses/Spring2008/Synthetic Biology/Computer Modelling Practicals/Practical 1/Report

   Practical 1: Report Structure


 * Name:
 * Department:

 Part I: Introduction to Computer Modelling
 * no report

 Part II: Getting to know CellDesigner
 * no report

 Part III: Building Your First Model: A --> B --> C
 * 1) Comments on the evolution of 'A', 'B', 'C' + screenshot.
 * 2) Parameter scan done on k1 and k2 + screenshots.
 * 3) Give k1 and k2 + screenshot.

 Part IV: Synthesis-Degradation Model
 * 1) Comments on the evolution of 'A' + screenshot
 * 2) Parameter scan on k1 and k2 + screenshots.
 * 3) Bonus: Analytical solution expression
 * 4) Half-life illustration Screenshot
 * 5) Bonus: Analytical expression of the half-life of compound 'A'.

 Part V: Michaelis-Menten Model
 * 1) Write down all the kinetics laws you had to define.
 * 2) Screenshot from the reaction simulation + comments on the different phases.
 * 3) Michaelis-Menten formula derivation.
 * 4) Expressions of Km and Vmax.
 * 5) Screenshot of the reaction networks.
 * 6) Screenshot of the simulation outputs + comments.