IGEM:IMPERIAL/2007/Projects/Cell by date/Modelling

=Cell by Date: Modelling=

 Introduction Specifications Design Modelling Implementation Testing/Validation Notes References </ul> <br style="clear:both">

Overview of Modelling
Welcome to our portal page for the modelling of Cell By Date

Cell by date tries to improve on printed cell by date as acting as a thermal exposure device, exploiting the thermal dependance of the rate of expression of a simple reporter system. We are looking at a variety of constructs to realise this behaviour.

Constructs to be Used
As can be seen in the above table all of our constructs have the same general form of a promoter upstream of a reporter. Looking at the rate of Fluorescent Protein (FP) produced :

$$\frac{d[FP]}{dt}=k_{FP}(t)-d_{FP}[FP] $$


 * 1) kFP : Function of Temperature.  k is based on the promoter used as promoters take time to turn on.
 * 2) dFP : Function of System.  May be considered to be a function of temperature as proteins degrade faster at higher temperatures.

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Transient Response of System
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Transfer Function of System
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Construct to be pursued

 * pTet

Refer to the constructs page for more information.