Registry of Standard Biological Models/Basic Component Models/Promoter RBS Coupled

CellML structure (CellML 1.1 spec)

 * Component: PromoterRBSCoupled
 * Units:
 * Imported from Environment component
 * Variables:
 * nbGeneCopies (public interface = in / init value = 1.0)
 * RiPSOutPerGene (public interface = none / init value = XXX)
 * RiPSOut (public interface = out / init value = depends on the promoter-RBS used)
 * MathML
 * $$ RiPSOut = nbGeneCopies*RiPSOutPerGene $$

CellML File
CellML Code









  



 

Comments

 * This component is simply a container providing the synthesis rate specific to a constitutive promoter coupled to a RBS
 * Having a model of a promoter and RBS coupled could mean that we have a constant synthesis rate of the downstream protein(s) (quasi steady state approx)
 * This parameter is easier to characterize experimentally. Using a calibrated GFP assay with none half-life, we know that at steady state (synthesis = degradation)