Kafatos:Tan, Lee Aun

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RESEARCH INTERESTS

My current postdoctoral research interest focuses on the participation of CLIP-serine proteases in the melanization of Plasmodium berghei in Anopheles gambiae. I have explored the use of recombinant proteins and various protease assays to assess the contribution of the various CLIP-serine proteases to the clearance and melanization of the parasite. The interaction of the mosquito immune system upon bacterial challange has also been explored and given that the immune system of an invertebrate is wholly innate, it was not surprising that many components of the immune cascade mediated by the CLIP-serine proteases function very similarly in the bacterial system.

EDUCATION

1996 B.Sc with Merit, Cell & Molecular Biology and Plant Biology, Deprtment of Biological Sciences, National University of Singapore

1997 B.Sc (Hons), Cell & Molecular Biology, Department of Biological Sciences, National University of Singapore

1998 M.Sc Integrative Bioscience, Department of Zoology, University of Oxford

2002 D.Phil Biochemistry, MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford

PREVIOUS APPOINTMENTS

2003 - 2005 Arthritis Research Campaign (ARC) Research Fellow, Gastroenterology and Autoimmunity Unit, Institute of Child Health, University College London

2006 - 2007 Coeliac UK Fellowship, Institute of Child Health, Gastroenterology and Autoimmunity Unit, University College London

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