Laboratory for the Investigation of the Biological Basis of Neurodevelopmental Disorders

People

 * Principal Investigator: Richard E. Frye, M.D., Ph.D.
 * Research Associate: Benjamin Malmberg
 * Graduate Assistant: Roger Wu
 * Graduate Assistant: Swapna Sreenivasula

Clinical Services and Studies

 * The Medically-Based Autism Clinic,
 * Tetrahydrobiopterin Supplementation for Children with Social and/or Language Delays
 * Clinical, Metabolic and Genetics Characteristics of Children with Autism and Mitochondrial Disorders
 * Effectiveness of Traditional and Alternative Treatments for Seizures in Autism
 * Brain Reorganization in Children with Autism
 * Brain Reorganization in Children with Subclinical Epileptiform Discharges

Basic Research Studies

 * Brain Reorganization Associated with Dyslexia
 * Brain Reorganization Associated with Premature Birth

Neuroimaging Analysis Methods

 * Dipole Modeling (MEG data)
 * Minimum Norm Estimates (MEG source modeling)
 * Freesurfer (segmentation, surface reconstruction and processing of surface models of the human cortex)
 * Multichannel least-squares linear regression (Granger Causality)