KC Huang Lab

Research
Our group tries to answer these questions using a systems biology approach, in which we integrate interacting networks of protein and lipids with the physical forces determined by the spatial geometry of the cell. We use theoretical and computational techniques to make predictions that we can verify experimentally using synthetic, chemical, or genetic perturbations.

We primarily focus on bacteria, in which the exquisite patterning of the interior in both space and time is critical for a wide variety of cellular functions. The wide variety of shapes and sizes that bacteria take on can be used as synthetic environment for studying the establishment of intracellular organization and the cellular response to perturbations in morphology. Ultimately, the manipulation of cell shape may provide a direct tool for engineering complex cellular behaviors.

Currently, we are interested in (i) the role of the cell wall in cell-shape determination, (ii) the regulation and mechanics of cell division, (iii) the spatial and temporal organization of the membrane, and (iv) the role of the membrane in transmembrane-protein interactions and ion channel gating.

Members

 * KC HUANG, Ph.D.   (Principal Investigator)
 * CAROLYN MAZENKO   (Administrative Assistant)
 * PAKPOOM (“TON”) SUBSOONTORN   (Rotation Student)
 * ISIS TRENCHARD  (Rotation Student)
 * Carolina Tropini  (Rotation Student)
 * Reza Nasiri Mahalati  (Rotation Student)
 * KRYSTAL ST. JULIEN  (Rotation Student)
 * JIANBIN WANG  (Rotation Student)
 * Leon Furchtgott

Contact Info
For information regarding positions as a rotation student, graduate student, or postdoc, please contact KC at kchuang [at] stanford [dot] edu

We are located in the Clark Center on the Stanford Medical School campus. Click here to access a map of the Stanford University campus.

Mailing Address

Department of Bioengineering James H. Clark Center S325, MC: 5444 318 Campus Drive West Stanford, CA 94305

Phone:   (650) 721-2483

Fax:     (650) 724-1922

Lab Phone: (650) 721-2669

Lab Protocols
Huang: Agarose Slides for Imaging