PGP:Transcriptome

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Purpose
The PGP will generate global gene expression profiling data on a subset of human volunteers, primarily using skin- and hair- derived primary cells, immortalized B-lymphocytes and iPS-derived tissues. Public data will be upload to MIAME-complliant Gene Expression Omnibus (GEO). This site will serve to coordinate and prioritize study samples among collaborators, and also to discuss various ways to interpret and analyze the data.

Collaborators

 * George Church Laboratory (HMS, Boston)
 * Kun Zhang Laboratory (UCSD, San Diego)
 * George Daley Laboratory (HMS, Boston)

Protocols

 * Sample Description
 * Tissue collection and cell lines
 * RNA processing and hybridization
 * Gene Expression Analysis

Projects

 * PGP1 fibroblasts and iPS-derived tissues
 * Comparative study of the first ten PGP volunteers