User:Kieran Smallbone/Linlog Kinetics

Linlog Kinetics
In order to model metabolism with minimal complexity, three sets of information are required over and above network stoichiometry:
 * Fluxes through the network.
 * Metabolite concentrations.
 * Elasticities - changes in reaction rates with reactant levels.

Once these values are known, a kinetic model may be defined using linlog kinetics smallbone07c visser03, whereby reaction rates v are assumed to change with concentrations x according to the functional form


 * $$v = v^\ast \left(1 + \sum_i \varepsilon_i \log \frac{x_i}{x_i^\ast} \right)$$

where v* denotes the reference flux, x* the reference concentrations and &epsilon; the corresponding elasticities.