User:Sheldon Park


 * Sheldon Park
 * University at Buffalo
 * 905 Furnas Hall
 * Buffalo, NY 14260
 * Email me through OpenWetWare

I work in the Department of Chemical and Biological Engineering at the University at Buffalo (SUNY). My research interest is to understand the structural basis of protein function. Once the structure-function relationship has been modeled, we validate the model by designing novel sequences consistent with the target function and implementing the designs experimentally.

Education


 * Ph.D, Harvard University
 * MS, MIT
 * BA, UC Berkeley

Research interests


 * Streptavidin
 * MDM2-p53
 * Bax
 * GPCR
 * Posttranslational modification

Selected Publications


 * 1) Park, S., Yang, X., Saven, J.G. Advances in Computational Protein Design, Curr Op in Struct Biol (2004) pmid=15313244
 * 2) Park, S., Saven, J.G. Statistical and molecular dynamics studies of buried waters in globular proteins, Proteins (2005) pmid=15937899
 * 3) Szep, S., Park, S., Boder, E.T., Van Duyne, G., Saven, J.G. Structural coupling between FKBP12 and buried water, Proteins (2009) pmid=18704951

Book
 * 1) Park, S.J. and Cochran, J.R. Protein Engineering and Design, CRC Press/Taylor & Francis (due summer 2009)

Use Links
 * Introductory tutorial
 * OpenWetWare help pages