CSBI.100

CSBi.100 class with Drew Endy
Friday, November 4, 2005

Readings

 * 1) Global transposon mutagenesis and a minimal Mycoplasma genome, Hutchison et al. URL
 * 2) Refactoring bacteriophage T7, Chan et al. URL
 * 3) Combining two genomes into one cell, Itaya et al. URL
 * 4) Adventures in Synthetic Biology (comic strip, to be made available the week of class)

Seed Questions

 * 1) Is there a difference between a "modelable" genome, and a "minimal" genome? What about a "modular" organism?
 * 2) Do we know enough about the parts of biological systems to put things back together?
 * 3) Is there a difference between "constructing" something, versus "creating" something?
 * 4) Is it easier, better, faster (etc) to understand something by tearing it apart? Or, by putting it back together?
 * 5) 