User:Mbennie/Notebook/Papers and Books/Leucine Zippers

CCAAT-Review pmid=12006103

Identification-bZIP pmid=12805554
 * Characterizes interactions between 49 leucine zippers using protein arrays
 * Observed that families make similar interactions
 * Observed high symmetry
 * Figure 2 of this paper shows interactions between 49 leucine zippers, color-coated by strength

Family Alignment for the BRLZ domain
 * Click "Family Alignment" to see list of leucine zippers
 * Might be useful in locating sequence information for various leucine zippers

Predicting-bZIP-interactions pmid=16359704
 * Leucine zippers have (abcdefg)n repeat - zippers interface with a, d, e, and g residues
 * Mostly computational information - predicting results generated by Comprehensive Identification of Human bZIP paper

Scissors-Grip-Model pmid=2683088
 * Leucine zippers are Y-shaped, recognize binding sites on DNA
 * "Dimer-forming region...hypothesized to consist of two amphipathic alpha helices, about 30 amino acids long, that adhere tightly to one another through a narrow hydrophobic spine punctuated every seven residues by a leucine side chain."
 * N-terminus side responsible for DNA binding
 * basic region-leucine zipper -> bZIP
 * DNA targets are "directly abutted, inverted repeats"

Leucinezipper-Early pmid=3289117
 * Introduces leucine zipper, information about similar methods of gene regulation: helix-turn-helix and zinc fingers
 * Compares several leucine zippers and identifies patterns (mainly leucine every seven aa)
 * Explains physical properties of leucine that make it ideal candidate for this role