Smolke:Kelsic:11-1-06 talk

Summary

 * It is useful to have independent control of cellular physical quantities.
 * Outline of a system for controlling the mean and variance of protein expression population distributions.

Information

 * given by Eric Kelsic to the Smolke Lab on 11-1-06
 * [[Media:11-1-06_Kelsic-Lab_Talk.ppt|PowerPoint slides]]

Additional

 * for more on the ideas of independence and reachability, look into control theory. Richard Murray at Caltech is working on a text, which is online: Feedback Systems - An Introduction for Scientists and Engineers.  Also, the idea of observability is interesting to think about, in terms of what cellular processes we can study and understand.
 * Chapter 6 - State Feedback - Reachability
 * Chapter 7 - Output Feedback - Observability
 * Also, the slides are best viewed with the soundtrack of MC Hammer's U Can't Touch This, a thoughtful piece on man's ability to use tools (symbolically the hammer) to manipulate and understand nature.

Comments

 * please leave comments or feedback here: -Kelsic


 * "sweetness is my weakness" - MC Hammer / Tsbayer