Helab:Publications


 * Archival publications (Since 2003)
 * 1) Zhang, W., Tang, C., and He, X. Synthesis and characterization of small (~100 um) ACA (alginate-chitosan-alginate) microcapsules for cell microencapsulation. 2011; in submission
 * 2) Zhang, W. and He, X. Microencapsulating and banking living cells for cell-based medicine. Journal of Healthcare Engineering 2011 (A special issue on surgical engineering); in review
 * He, X. Preservation of embryonic stem cells. In Methodological Advances in the Culture, Manipulation and Utilization of Embryonic Stem Cells for Basic and Practical Applications, Ed: Atwood, C.; Vienna, Austria: InTech Publisher, pp113-138, 2011 Read
 * Yao, K., Wang, J., Zhang, W., Lee, J.S., Wang, C., Chu, F., He, X., Tang, C. Degradable rosin ester-caprolactone graft copolymers, Biomacromolecules 2011; 12: 2171-2177 Read
 * He, X. Thermostability of biological systems: Fundamentals, challenges, and quantification. The Open Biomedical Engineering Journal 2011; 5: 47-73 Read
 * 1) Gilstrap, K., Hu, X., Lu, X., and He, X. Nanotechnology for energy-based cancer therapies. American Journal of Cancer Research 2011; 1(4): 508-520 Read
 * 2) Zhang, X., Wan, G., Berger, F.G., He, X., and Lu, X. The ATM kinase induces microRNA biogenesis in DNA damage. Molecular Cell 2011; 41: 371-383 Read
 * 3) Yang, G., Veres, M., Szalai, G., Zhang, A., Xu, L. X., and He, X. Biotransport phenomena in freezing mammalian oocytes. Annals of Biomedical Engineering 2011; 39(1): 580-591 Read
 * 4) Zhang, W., Gilstrap, K., Wu, L., K.C., R. B., Moss, M. A., Wang, Q., Lu, X., and He, X. Synthesis and characterization of thermally responsive Pluronic F127-chitosan nanocapsules for controlled release and intracellular delivery of small molecules. ACS Nano 2010; 4(11): 6747-6759 Read
 * 5) Yang, G., Gilstrap, K., Zhang, A., Xu, L.X., and He, X. Collapse temperature of solutions important for lyopreservation of living cells at ambient temperature. Biotechnology and Bioengineering 2010; 106(2): 247-259 (Selected by the journal as cover story) Read
 * 6) Zhang, W., Yang, G., Zhang, A., Xu, L.X., and He, X. Preferential vitrification of water in small (~100 µm) alginate microcapsules significantly augments cell cryopreservation by vitrification. Biomedical Microdevices 2010; 12(1): 89-96 Read
 * 7) Zhang, W., Rong, J, Wang, Q., and He, X. The encapsulation and intracellular delivery of trehalose using a thermally responsive nanocapsule. Nanotechnology 2009; 20(27): Article No. 275101 (14pp) Read
 * 8) Zhang, W. and He, X. Encapsulation of living cells in small (~100 µm) alginate microcapsules by electrostatic spraying: a parametric study. Journal of Biomechanical Engineering 2009; 131: Article No. 074515 (6pp) Read
 * 9) Yang, G., Zhang, A., Xu, L.X., and He, X. Modeling the cell type dependence of diffusion-limited intracellular ice nucleation and growth: Implications for cell cryopreservation by both vitrification and slow freezing. Journal of Applied Physics 2009; 105: Art. No. 114701 (11 pp) Read
 * He, X., Bhowmick, S., and Bischof, J.C. Thermal therapy in urologic systems: A comparison of Arrhenius and thermal isoeffective dose (TID) models in predicting hyperthermic injury. Journal of Biomechanical Engineering 2009; 131: Article No. 074507 (12pp) Read
 * Li, D. and He, X. Desiccation induced structural alterations in a 66-amino acid fragment of an anhydrobiotic nematode late embryogenesis abundant (LEA) protein. Biomacromolecules 2009; 10: 1469-1477 Read
 * He, X., Fowler, A., Menze, M., Hand, S., and Toner, M. Desiccation kinetics and biothermodynamics of trehalose solutions in thin films: Implication for lyopreservation. Annals of Biomedical Engineering 2008; 36(8): 1428-1439 Read
 * He, X., Park, E., Fowler, A., Yarmush M., and Toner, M. Vitrification by ultra-fast cooling at a low concentration of cryoprotectants in a quartz microcapillary: A study using murine embryonic stem cells. Cryobiology 2008; 56(3): 223-232 Read
 * 1) Risco, R., Elmoazzen, H., Doughty, M., He, X., and Toner, M. Thermal performance of quartz capillaries for vitrification. Cryobiology 2007; 55(3): 222-229 Read
 * He, X., Fowler, A., and Toner, M. Water activity and mobility in solutions of glycerol and small molecular weight sugars: Implication for cryo- and lyo- preservation. Journal of Applied Physics 2006; 100 (7): Art. No. 074702 (11 pp) Read
 * He, X., Amin, A., Fowler A., and Toner, M. Thermally induced introduction of trehalose into primary rat hepatocytes. Cell Preservation Technology 2006; 4(3): 178-187 Read
 * 1) Aksan, A., Irimia, D., He, X., and Toner, M. Desiccation kinetics of biopreservation solutions in micro-channels. Journal of Applied Physics 2006; 99 (6): Art. No. 064703 (9 pp) Read
 * He, X. and Bischof, J. C. Analysis of thermal stress in cryosurgery of kidneys. Journal of Biomechanical Engineering 2005; 127(4): 656-661 Read
 * 1) Bischof, J. C. and He, X. Thermal stability of proteins. Annals of the New York Academy of Sciences 2005; 1066: 12-33 Read
 * He, X. and Bischof, J. C. The kinetics of thermal injury in human renal carcinoma cells. Annals of Biomedical Engineering 2005; 33(4): 502-510 Read
 * He, X., Wolkers, W. F., Crowe, J. H., Swanlund D. J., and Bischof J. C. In situ thermal denaturation of proteins in dunning AT-1 prostate cancer cells: Implication for hyperthermic cell injury. Annals of Biomedical Engineering 2004; 32(10): 1384-1398 Read
 * He, X., McGee, S., Coad, J. E., Schmidlin, F., Iaizzo, P. A., Swanlund, D. J., Rudie, E., Kluge, S. and Bischof, J. C. Investigation of the thermal and tissue injury behavior in microwave thermal therapy using a porcine kidney model. International Journal of Hyperthermia 2004; 20(6): 567-593 Read
 * 1) Chao, B. H., He, X., and Bischof, J. C. Pre-existing inflammation induced by TNF-α augments cryosurgical injury on human prostate cancer. Cryobiology 2004; 49(1): 10-27 Read
 * He, X. and Bischof, J. C. Quantification of temperature and injury in thermal therapy and cryosurgery. Critical Reviews in Biomedical Engineering 2003; 31(5): 355-421 Read