Gautier Lab:Research Interests

Research Interests
Page under construction

We use the Xenopus laevis cell-free extracts system to study processes in DNA replication and repair.

We are interested in


 * elucidating the mechanisms of ATM activation


 * studying the role of the Mre11-Rad50-Nbs1 complex in double-strand break repair


 * using cell-free extracts to identify small molecules that modulate DNA replication, DNA repair or the DNA damage response


 * studying the role of Fanconi anemia proteins in DNA replication and repair


 * defining the mechanism of double-strand break resection with a focus on the role of CtIP


 * studying the role of BRCA1/BARD1 in the DNA damage response


 * understanding the regulation of DNA replication by MCM proteins


 * understanding the mechanism by which cMYC regulates DNA replication

see our frogs

Leave us a message on our talk page.